Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-03-18Clinical Trial Update: Treatment of Depression in Mothers in Home Visitation [NA]
This clinical trial update notes that a study examining treatments for depression in mothers enrolled in a home visitation program has compl…
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CLINICAL_TRIALS trial_result · 2013-03-15Clinical Trial Update: An Eight-week Study of SSR411298 as Treatment for Major Depressive Disorder in Elderly Patients [Phase 2]
A Phase 2 eight-week trial of SSR411298 for major depressive disorder in elderly patients has been completed.
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FDA approval · 2013-03-14FDA Approved: OLANZAPINE AND FLUOXETINE — Supplemental Application (Par Health USA, LLC)
FDA approved a supplemental application for a generic olanzapine and fluoxetine combination submitted by Par Health USA, LLC. The product is…
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CLINICAL_TRIALS trial_result · 2013-03-14Clinical Trial Update: Depression Outcomes Study of Exercise [Phase 1]
A Phase 1 clinical trial evaluating the impact of exercise on depression outcomes in individuals with unipolar depression has completed. The…
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CLINICAL_TRIALS trial_result · 2013-03-13Clinical Trial Update: Proton MRS Study of SSRI-Zolpidem Interactions [EARLY_Phase 1]
Early-phase 1 study used proton magnetic resonance spectroscopy to examine SSRI-zolpidem interactions; the trial has completed.
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CLINICAL_TRIALS trial_result · 2013-03-12Clinical Trial Update: Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers [NA]
A completed clinical trial evaluating interpersonal therapy-based treatment to prevent postpartum depression in adolescent mothers.
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Treatment of Depression in Parkinson's Disease Trial [Phase 2]
Phase 2 trial evaluating a treatment for depression in Parkinson's disease has completed and results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Internet-administrated Treatment of Anxiety Disorders [NA]
A completed clinical trial evaluating an internet-based treatment for anxiety disorders, with related consideration of depression.
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FDA approval · 2013-03-04FDA Approved: DESVENLAFAXINE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved desvenlafaxine (brand Pristiq) from Sun Pharmaceutical Industries, Inc. in an original NDA for the treatment of major depressiv…
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CLINICAL_TRIALS trial_result · 2013-02-27Clinical Trial Update: Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure [Phase 2, Phase 3]
Phase 2/3 trial evaluating antidepressant treatment for depression in individuals with chronic heart failure has been completed, with result…
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CLINICAL_TRIALS trial_result · 2013-02-27Clinical Trial Update: Ultrabrief Pulsewidth Electroconvulsive Therapy (ECT) [Phase 4]
This clinical trial update reports results from a Phase 4 study of ultrabrief pulsewidth electroconvulsive therapy for adults with major dep…
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Study Comparing Outcomes for Patients With Treatment Resistant Depression Who Receive VNS Therapy at Different Doses [Phase 4]
A Phase 4 study reports results comparing outcomes for treatment-resistant depression patients treated with VNS therapy at different dose le…
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Helping African American Prostate Cancer Survivors and Their Partners Cope With Challenges After Surgery for Prostate Cancer [NA]
This Clinical Trial Update notes the completion of a study aimed at helping African American prostate cancer survivors and their partners co…
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CLINICAL_TRIALS trial_result · 2013-02-22Clinical Trial Update: Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
This update reports results from a youth-focused trial evaluating the effectiveness and tolerability of a second-generation antipsychotic ac…
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CLINICAL_TRIALS research · 2013-02-22Clinical Trial Update: A Study of Ketamine as an Antidepressant [Phase 2]
Phase 2 clinical trial investigating ketamine as an antidepressant for major depressive disorder. The current status is unknown.
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CLINICAL_TRIALS research · 2013-02-20Clinical Trial Update: The Metabolic Effects of Antidepressants in Patients Diagnosed With Major Depressive Disorder
This entry documents a clinical trial studying the metabolic effects of antidepressants in patients with Major Depressive Disorder, with an …
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FDA approval · 2013-02-14FDA Approved: PRISTIQ EXTENDED-RELEASE — Supplemental Application (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.)
The FDA approved a supplemental application to authorize the extended-release formulation of desvenlafaxine succinate (Pristiq Extended-Rele…
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CLINICAL_TRIALS trial_result · 2013-02-13Clinical Trial Update: A Pilot Study of the Use of Magnetic Seizure Therapy for Depression [Phase 2]
The document reports the completion of a Phase 2 pilot trial evaluating Magnetic Seizure Therapy for treatment-resistant depression.
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CLINICAL_TRIALS trial_result · 2013-02-13Clinical Trial Update: Stress Reactivity of Physical Stressor on Depression [NA]
This ClinicalTrials.gov entry indicates a completed study sponsored by Universidade Federal do Rio de Janeiro examining the effects of a phy…
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CLINICAL_TRIALS trial_result · 2013-02-12Clinical Trial Update: Quetiapine Prolong, Escitalopram and Hypothalamic-pituitary-adrenocortical (HPA) Axis Activity in Depressed Patients [Phase 3]
A Phase 3 trial evaluating quetiapine prolonged-release in combination with escitalopram and its effect on HPA axis activity in major depres…
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FDA approval · 2013-02-12FDA Approved: QUETIAPINE — Original Application (Ascend Laboratories, LLC)
FDA approved Ascend Laboratories' generic quetiapine fumarate under an original ANDA, making a generic version of quetiapine available.
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CLINICAL_TRIALS trial_result · 2013-02-08Clinical Trial Update: Adapting Cognitive Behavioral Therapy (CBT) for Chinese Americans [NA]
A completed clinical trial investigating the adaptation of Cognitive Behavioral Therapy for Chinese American individuals with major depressi…
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CLINICAL_TRIALS trial_result · 2013-02-08Clinical Trial Update: A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder [Phase 4]
A Phase 4 neuroimaging study examining brain activity in major depressive disorder and bipolar disorder has completed.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: Efficacy and Safety Curcumin in Depression [Phase 4]
This clinical trial update reports efficacy and safety results of a Phase 4 study evaluating curcumin for major depressive disorder. The stu…
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Trigeminal Nerve Stimulation for Post Traumatic Stress Disorder (PTSD) and Depression [Phase 1]
Phase 1 trial update on trigeminal nerve stimulation for depression and post-traumatic stress disorder.