Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-04-03Clinical Trial Update: Safety, Efficacy, and Tolerability of Vilazodone in Major Depressive Disorder [Phase 4]
Phase 4 clinical trial results evaluating the safety, efficacy, and tolerability of vilazodone in adults with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2014-04-03Clinical Trial Update: Reducing CVD Risk in Caregivers: A Brief Behavioral Activation Intervention [NA]
This clinical trial evaluated a brief behavioral activation intervention to reduce cardiovascular risk in caregivers and monitored depressiv…
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: Multiple-Dose Pharmacokinetics (PK), and Pharmacodynamic (PD) Effect of NSI-189 Phosphate in Depression Patient Subjects [Phase 1]
Phase 1 study assessing multiple-dose pharmacokinetics and pharmacodynamics of NSI-189 Phosphate in adults with depression; the trial status…
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: A Study of the Neurobiology of Depression [Phase 4]
Phase 4 clinical trial update from Eli Lilly on Major Depressive Disorder and the neurobiology of depression has completed. Results were pos…
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CLINICAL_TRIALS trial_result · 2014-04-01Clinical Trial Update: Open-label Safety Extension Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults [Phase 3]
An open-label Phase 3 safety extension evaluated long-term safety and tolerability of vortioxetine at 2.5, 5, and 10 mg in adults with Major…
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CLINICAL_TRIALS trial_result · 2014-04-01Clinical Trial Update: The Effect of Mirror Education for Women Undergoing Mastectomy [NA]
Clinical trial update on mirror education for women undergoing mastectomy, assessing effects on emotional distress, anxiety, and depression.
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CLINICAL_TRIALS trial_result · 2014-03-31Clinical Trial Update: Efficacy of Vortioxetine (Lu AA21004) in the Prevention of Relapse of Major Depressive Episodes [Phase 3]
Phase 3 trial evaluating vortioxetine for relapse prevention in adults with major depressive disorder; the study completed and results were …
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CLINICAL_TRIALS trial_result · 2014-03-31Clinical Trial Update: A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD) [NA]
This entry notes the completion of a group psychotherapy trial for veterans and military personnel with posttraumatic stress disorder, with …
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CLINICAL_TRIALS research · 2014-03-31Clinical Trial Update: TRIAD Project: Qualitative Study of Adolescent Depression and Smoking
A completed qualitative trial update from the TRIAD Project exploring how adolescent depression relates to smoking behavior.
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FDA approval · 2014-03-28FDA Approved: GEODON — Supplemental Application (Viatris Specialty LLC)
FDA approved a supplemental application for GEODON (ziprasidone mesylate) submitted by Viatris Specialty LLC.
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CLINICAL_TRIALS trial_result · 2014-03-28Clinical Trial Update: Exploratory Study on the Mood and Cytokine Levels in Female Healthy Participants and Major Depressive Disorder Patients [EARLY_Phase 1]
This clinical trial update notes the completion of an exploratory early-phase study examining mood and cytokine levels in female healthy par…
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CLINICAL_TRIALS trial_result · 2014-03-28Clinical Trial Update: Reducing the Risk of Developing Major Depression in Adolescents/Young Adults With Minor Depression/Depression Symptoms
This trial investigated whether an intervention could reduce the risk of progressing to major depressive disorder in adolescents/young adult…
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CLINICAL_TRIALS research · 2014-03-28Clinical Trial Update: Interpersonal Treatment Program to Prevent Depression and Post-Traumatic Stress Disorder in Low-Income Pregnant Women With Partner Abuse [Phase 1]
A Phase 1 clinical trial of an interpersonal treatment program to prevent depression and post-traumatic stress disorder in low-income pregna…
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CLINICAL_TRIALS research · 2014-03-27Clinical Trial Update: Web-Based Survey of Pain, Stress and Complementary and Alternative Medicine
A completed UCLA-led web-based survey study assessing pain, stress, and the use of complementary and alternative medicine across conditions …
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: A Study of Vortioxetine (Lu AA21004) in Comparison to Agomelatine in Adults Suffering From Major Depression With Inadequate Response to Previous Medication [Phase 3]
This Phase 3 study compared vortioxetine (Lu AA21004) with agomelatine in adults with major depressive disorder who had an inadequate respon…
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CLINICAL_TRIALS trial_result · 2014-03-20Clinical Trial Update: Effectiveness of Supplemental Calcium in Preventing Postpartum Depression [Phase 4]
A Phase 4 clinical trial evaluated whether supplemental calcium can prevent postpartum depression. The study has completed.
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Effectiveness of a Technology Assisted Behavioral Intervention in Assisting People With Major Depressive Disorder [Phase 1]
Phase 1 clinical trial evaluating the effectiveness of a technology-assisted behavioral intervention for major depressive disorder has compl…
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Enhanced Medical Rehabilitation for Disablement [Phase 2]
Phase 2 trial update on Enhanced Medical Rehabilitation for Disablement; the study is reported as completed.
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FDA approval · 2014-03-18FDA Approved: MIRTAZAPINE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for Mylan Pharmaceuticals' generic mirTAZAPine (mirtazapine).
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Safety Study of Escitalopram in Children 7 to 11 Years of Age With Major Depressive Disorder [Phase 4]
Phase 4 safety study of escitalopram in children aged 7 to 11 with major depressive disorder has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Clinical and Biological Characteristics of Psychotic Depression
A completed clinical trial examining the clinical and biological characteristics of psychotic depression (major depressive disorder with psy…
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Psychosocial Treatment for Women With Depression and Pain [NA]
The clinical trial update notes the completion of a psychosocial treatment study for women with comorbid pelvic pain and depression.
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CLINICAL_TRIALS trial_result · 2014-03-12Clinical Trial Update: Treatment of SSRI-Resistant Depression In Adolescents (TORDIA) [Phase 2, Phase 3]
This update notes the completion of the TORDIA trial assessing treatment strategies for SSRI-resistant depression in adolescents (Phase 2 an…
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CLINICAL_TRIALS trial_result · 2014-03-12Clinical Trial Update: Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD [NA]
This clinical trial compared sequenced versus integrated delivery of treatment for adolescents with depression and substance use disorders; …
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CLINICAL_TRIALS trial_result · 2014-03-12Clinical Trial Update: Testing the Effectiveness of Adolescent Depression Prevention Programs (The OregonBlues Study) [Phase 2, Phase 3]
This clinical trial update notes completion of Phase 2 and Phase 3 testing for adolescent depression prevention programs (the OregonBlues St…