Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: Serotonin Transporter Genetic Variation and Amygdala Responses to Antidepressant Medications in Major Depression [Phase 4]
Phase 4 clinical trial update examining how serotonin transporter genetic variation influences amygdala responses to antidepressants in majo…
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: Individually Based Psychosocial Rehabilitation for Older People With Serious Mental Illness (SMI) [Phase 1]
Phase 1 completion of a trial evaluating individually based psychosocial rehabilitation for older adults with serious mental illness, includ…
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CLINICAL_TRIALS research · 2014-05-07Clinical Trial Update: "Mindfulness vs Psychoeducation in Bipolar Disorder" [NA]
A clinical trial comparing mindfulness versus psychoeducation for individuals with bipolar disorder and depressive symptoms; sponsored by In…
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CLINICAL_TRIALS trial_result · 2014-05-06Clinical Trial Update: The Effect of Melatonin on Depression, Anxiety, Cognitive Function and Sleep Disturbances in Breast Cancer Patients [Phase 2, Phase 3]
The trial evaluated melatonin for depression, anxiety, cognitive function, and sleep disturbances in breast cancer patients across phase 2/3…
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CLINICAL_TRIALS trial_result · 2014-05-05Clinical Trial Update: Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression [NA]
Feasibility study completed for a low energy AC magnetic field to test clinical efficacy in major depressive disorder; results posted in 201…
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Nurse-led Case Management for Diabetes and Cardiovascular Disease Patients With Depression [NA]
A completed clinical trial evaluating nurse-led case management for patients with depression and comorbid diabetes and cardiovascular diseas…
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Duloxetine Treatment in Elderly With Dysthymia [Phase 4]
Phase 4 trial evaluating duloxetine in elderly patients with depression and dysthymic disorder has completed, with results posted in 2014. S…
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CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: Low Field Magnetic Stimulation in Mood Disorders Using the LFMS Device [NA]
Completed clinical trial evaluating low field magnetic stimulation (LFMS) for mood disorders, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-04-28Clinical Trial Update: Effectiveness of rTMS With Double-Cone-Coil in Patients With Major Depression [NA]
Clinical trial update reporting the effectiveness of repetitive transcranial magnetic stimulation using a double-cone coil in patients with …
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CLINICAL_TRIALS withdrawal · 2014-04-28Clinical Trial Update: Implementing Telemedicine-Based Collaborative Care for MDD in Contract CBOCs [NA]
The trial investigating telemedicine-based collaborative care for major depressive disorder in VA contract community-based outpatient clinic…
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Dopamine Neurotransmission in Major Depression
A completed clinical trial update from McLean Hospital examining dopamine neurotransmission in Major Depressive Disorder and Anhedonia.
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Combining Medications to Enhance Depression Outcomes [Phase 4]
Phase 4 NIMH-sponsored clinical trial evaluating combining medications to improve outcomes in Major Depressive Disorder; the study is comple…
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FDA approval · 2014-04-22FDA Approved: QUETIAPINE FUMARATE — Supplemental Application (BluePoint Laboratories)
FDA approved a supplemental application for quetiapine fumarate submitted by BluePoint Laboratories. This action grants updated regulatory a…
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CLINICAL_TRIALS trial_result · 2014-04-22Clinical Trial Update: A Working Memory Training to Decrease Rumination in Depressed and Anxious Individuals [NA]
This clinical trial update notes the completion of a study evaluating whether working memory training can decrease rumination in individuals…
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CLINICAL_TRIALS trial_result · 2014-04-22Clinical Trial Update: Tackling Depression and Anxiety: A Working Memory Intervention [NA]
This entry reports the completion of a clinical trial evaluating a working memory intervention for individuals with major depressive disorde…
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Understanding Brain Reward Responses in Individuals With Major Depressive Disorder
A completed clinical trial examining brain reward responses in individuals with major depressive disorder.
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FDA approval · 2014-04-17FDA Approved: VIIBRYD — Supplemental Application (Allergan, Inc.)
FDA notes a supplemental application for VIIBRYD (vilazodone hydrochloride) submitted by Allergan, Inc., related to the existing NDA for vil…
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Treatment for Adolescents With Depression Study (TADS) [Phase 3]
The Treatment for Adolescents With Depression Study (TADS), a Phase 3 trial for adolescents with major depressive disorder, has completed.
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Do Antidepressants Induce Metabolic Syndromes METADAP Study [NA]
A METADAP trial update indicates the study investigating whether antidepressants cause metabolic syndromes in patients with Major Depressive…
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FDA label_change · 2014-04-16FDA Approved: CELEXA — Supplemental Application (Allergan, Inc.)
FDA approved a supplemental application for Celexa (citalopram) by Allergan, Inc., for a label update.
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CLINICAL_TRIALS trial_result · 2014-04-11Clinical Trial Update: Effectiveness of a Web-based Prevention Program for Postpartum Depression [NA]
Clinical trial evaluating the effectiveness of a web-based prevention program for postpartum depression, with the study status reported as c…
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Hatha Yoga in Improving Physical Activity, Inflammation, Fatigue, and Distress in Breast Cancer Survivors [NA]
Completed clinical trial evaluating Hatha yoga to improve physical activity, inflammation, fatigue, and distress in breast cancer survivors;…
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CLINICAL_TRIALS research · 2014-04-10Clinical Trial Update: Neuroimaging Study of Bupropion Treatment in Patients With Major Depressive Disorder [Phase 4]
A Phase 4 clinical trial update describing a neuroimaging study of bupropion in patients with major depressive disorder, which has completed…
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CLINICAL_TRIALS trial_result · 2014-04-08Clinical Trial Update: Preventing Mid- and Later-Life Work Limitations [NA]
The document notes the completion of a Tufts Medical Center clinical trial focused on preventing mid- and later-life work limitations in peo…
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FDA approval · 2014-04-07FDA Approved: VIIBRYD — Supplemental Application (Allergan, Inc.)
The FDA approved a supplemental application for VIIBRYD (vilazodone hydrochloride) submitted by Allergan, Inc., updating the product's label…