Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder
Karolinska Institutet is conducting a trial to identify psychobiological markers to improve diagnosis and predict affective episodes in bipo…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Deep Brain Stimulation (DBS) Therapy for Treatment Resistant Depression [NA]
Clinical trial update on deep brain stimulation therapy for treatment-resistant depression, with status active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
This clinical trial update describes a retrospective observational study evaluating blood-based biomarkers for diagnosing and monitoring sev…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: IWLS for Major Depressive Disorder: An Open-Label Study of Safety, Tolerability, and Efficacy [NA]
Open-label clinical trial updating the safety, tolerability, and efficacy of IWLS for major depressive disorder; status is ACTIVE_NOT_RECRUI…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Exploring Mechanisms for Neuropsychiatric Symptoms of Parkinson Disease Using Transcranial Direct Current Stimulation [NA]
This clinical trial update indicates that the Johns Hopkins University study exploring transcranial direct current stimulation to understand…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: MISAPSY: Childhood Maltreatment, Food Insecurity, Psychological Distress and Professional Integration Among Socioeconomically Disadvantaged Young Adults [NA]
A new, not-yet-recruiting clinical trial in France investigates how childhood maltreatment, food insecurity, and psychological distress infl…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Depression Among Medical Students at Sohag University
A clinical trial sponsored by Sohag University investigating major depressive disorder is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: The BEAR Program for Women With Trauma Who Have Suicidal Thoughts [NA]
Stanford is conducting the BEAR Program, a clinical trial recruiting women with trauma who have suicidal thoughts to study interventions for…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Virtual Reality-Enhanced Behavioral Activation for Older Adults With Depression [NA]
Stanford University is recruiting for a clinical trial evaluating virtual reality-enhanced behavioral activation to treat major depressive d…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Individualized (fMRI-guided) TMS Treatment for Depression [NA]
University of Pennsylvania is conducting a trial testing individualized fMRI-guided transcranial magnetic stimulation for depression, includ…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Dynamic Network Response to TMS Treatment
A Goethe University-sponsored clinical trial is investigating dynamic network responses to transcranial magnetic stimulation for major depre…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Fluoxetine on Emotional Experience (FLEX) Study [NA]
A clinical trial investigating fluoxetine's effect on emotional experience in adults with major depressive disorder and irritability; recrui…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: A Study of ONO-1110 in Patients With Major Depressive Disorder [Phase 2]
Clinical trial update indicates Ono Pharmaceutical's ONO-1110 is in Phase 2 testing for major depressive disorder and is currently not recru…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Personalizing Mental Health Treatment for Youth and Families [NA]
Clinical trial update from the University of Oregon on personalizing mental health treatment for youth and families. The study is not yet re…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors [NA]
This entry reports an active, non-recruiting clinical trial evaluating abbreviated MBCT to treat depression in older African American/Black …
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Bridging the Gap: Implementing BRIDGES [NA]
Clinical trial update from Université Catholique de Louvain on implementing the BRIDGES program for depression in inactive people; the study…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Feasibility and Acceptability of Peer Intervention for Improving Mental Health Among People Accessing Hormone Care [NA]
This ClinicalTrials.gov update describes a feasibility and acceptability study of a peer intervention to improve mental health among people …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons [NA]
Pilot effectiveness trial of an ACT self-help workbook tailored for prisons, evaluating its impact on anxiety and depression.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Michigan Men's Diabetes Project III(MenDIII): Mind and Motion [NA]
A University of Michigan trial called MenDIII Mind and Motion is currently recruiting participants with type 2 diabetes and depressive sympt…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: START NOW Adapted: Culturally Adapted Version of START NOW [NA]
This clinical trial update indicates that the START NOW Adapted, a culturally adapted version of the START NOW program, is currently recruit…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression [Phase 2]
A Phase 2 clinical trial evaluating computerized cognitive behavioral therapies for suicide prevention and depression is currently recruitin…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
This clinical trial update examines whether testosterone levels are associated with dementia and adverse mental health outcomes, including a…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Real-World NeuroModulate: Investigating Non-Invasive Brain Stimulation for Neuropsychiatric Disorders at TUM
Real-World NeuroModulate at Technical University of Munich is investigating non-invasive brain stimulation for depressive disorders and is c…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Evaluation of the Concordance Between Measures Obtained by a Medical Device for Emotional Monitoring (EMOCARE) and the Patient Health Questionnaire (PHQ-9) Score in Patients With Mild to Severe Depressive Episode [NA]
This clinical trial aims to evaluate how well measurements from the EMOCARE emotional monitoring device concord with PHQ-9 scores in patient…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: A Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive Disorder [Phase 2]
This document reports the completion of a Phase 2 trial evaluating the safety and efficacy of SEP-363856 in adults with major depressive dis…