Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Preventing Psychological Distress and Suicidal Behaviours: a Web-based and Mobile Suicide Prevention Intervention in the General Population [NA]
The document reports the completion of a web-based and mobile suicide prevention intervention tested in the general population. It lists the…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Epidemiological Study on the Prevalence of Mental Disorders in Slovakia
A completed epidemiological study from Comenius University assessing the prevalence of several mental disorders in Slovakia.
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FDA approval · 2026-02-18FDA Approved: ARIPIPRAZOLE — Original Application (Aurobindo Pharma Limited)
FDA approved the original ANDA for aripiprazole from Aurobindo Pharma Limited, providing a generic version of the antipsychotic. The approva…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida [NA]
This clinical trial evaluates a clinician-supported mobile app intended to reduce PTSD, anxiety, depression, and sleep disturbance symptoms …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Virtual Reality in Hemodialysis to Improve Psychological Well-being [NA]
This ClinicalTrials.gov update describes a study evaluating virtual reality during hemodialysis to improve psychological well-being in patie…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Mechanisms Of Change in Psychotherapy: The Effects of Cognitive Behavioral Therapy and Psychodynamic Therapy in Once - Versus Twice - Weekly Sessions on Outcomes in Depression. [NA]
A clinical trial protocol assessing mechanisms of change in psychotherapy, comparing cognitive-behavioral therapy and psychodynamic therapy …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Interest of Adaptated Physical Activity (APA) on the K Recovery Constant, Reflecting the Rate of Muscle Oxygenation Recovery in Menopausal Women Suffering From Depression [NA]
This clinical trial update indicates ongoing research on adapted physical activity to improve muscle oxygenation recovery in menopausal wome…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: GynMDD Add-On to Supportive Psychotherapy in Mild to Moderate Depression [NA]
ClinicalTrials.gov entry for an add-on intervention called GynMDD Add-On to Supportive Psychotherapy for mild-to-moderate depression is NOT_…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness [Phase 2]
A Phase 2 clinical trial update from Brigham and Women's Hospital seeks novel transcranial magnetic stimulation targets for psychiatric illn…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs [NA]
This clinical trial update reports on the effectiveness and implementation of electronic screening (eScreening) in VA Post-9/11 transition p…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study [Phase 3]
Phase 3 comparative effectiveness study comparing esketamine (Spravato) to ketamine for depression is currently recruiting to assess equival…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital [NA]
A Massachusetts General Hospital-sponsored clinical trial at Worcester Recovery Center and Hospital is currently recruiting. The study targe…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction - Beta Trial [NA]
This completed beta trial assessed the feasibility and acceptability of an online Acceptance and Commitment Therapy (ACT) intervention for d…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: To Investigate the Change of Brain and Autonomic Function From Different Protocols of Repeated Transcranial Magnetic Stimulation Therapy for Patients With Post-traumatic Stress Disorder Comorbid Major Depressive Disorder [NA]
A clinical trial evaluating different protocols of repetitive transcranial magnetic stimulation (rTMS) to assess brain and autonomic functio…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: The Role of mGluR5 in CBT-I [Phase 4]
A Phase 4 clinical trial update investigating the role of mGluR5 modulation in CBT-I for adults with Major depressive disorder, currently re…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Telehealth Music Therapy for Adults With Endocrine Disorder and Depression [NA]
Appalachian State University is conducting a telehealth music therapy study for adults with endocrine disorders and depression, with recruit…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: DBS for TRD With the Medtronic Summit RC+S [NA]
This clinical trial update reports that a deep brain stimulation approach using the Medtronic Summit RC+S for treatment-resistant depression…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With Aticaprant [Phase 3]
A Phase 3 trial evaluating aticaprant 10 mg as adjunctive therapy for adults with major depressive disorder and moderate-to-severe anhedonia…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: VR Pupillometry in Cognitive Impairment
A clinical trial update announcing a recruiting study on virtual reality pupillometry for cognitive impairment, including Alzheimer's diseas…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women [NA]
This clinical trial update indicates that BTL Industries Ltd. is recruiting for a study evaluating the BTL-699-2 and HPM-6000UF devices to i…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Stellate Ganglion Block for Prevention of Post Mastectomy Depression [NA]
Clinical trial from Mansoura University testing whether stellate ganglion block can prevent postmastectomy depression. The study enrolls mas…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Rapid Antidepressant Improvement Secondary to Excitatory Brain Responses [Phase 4]
A Phase 4 clinical trial examining rapid antidepressant improvements linked to excitatory brain responses in major depressive disorder has c…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression [Phase 2]
A Phase 2 clinical trial evaluating specialized pro-resolving lipid mediators for treatment-resistant depression is active but not recruitin…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Individualized Neuromodulation for Anhedonic Depression [NA]
A clinical trial evaluating individualized neuromodulation for anhedonic depression has completed.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Stereotactic Radiotherapy Treatment for Treatment-resistant Depression [NA]
A clinical trial at Capital Medical University is evaluating stereotactic radiotherapy for treatment-resistant depression and is currently e…