Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Buprenorphine for Treatment Resistant Depression [Phase 3]
Phase 3 trial evaluating buprenorphine for treatment-resistant depression has completed. Results were posted in March 2016.
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FDA approval · 2016-03-17FDA Approved: DESIPRAMINE HYDROCHLORIDE — Original Application (Amneal Pharmaceuticals NY LLC)
FDA approved Amneal Pharmaceuticals NY LLC's desipramine hydrochloride as a generic product through an original ANDA. Desipramine is used to…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Study of Intravenous NRX-1074 in Patients With Major Depressive Disorder [Phase 2]
Phase 2 study of intravenous NRX-1074 in major depressive disorder has completed; no efficacy results are provided in the snippet.
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CLINICAL_TRIALS research · 2016-03-17Clinical Trial Update: Activation on LDPC Cortex With Different Acupoints: An fNIRS Study [NA]
A clinical trial from The University of Hong Kong investigates activation of the LDPC cortex using different acupoints in depression, assess…
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FDA approval · 2016-03-16FDA Approved: PRISTIQ EXTENDED-RELEASE — Supplemental Application (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.)
The FDA approved a supplemental application to add an extended-release formulation of desvenlafaxine succinate (Pristiq Extended-Release) by…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Framingham Offspring Study: Psychosocial Risk Factors
Update on the Framingham Offspring Study focusing on psychosocial risk factors related to cardiovascular conditions; the study is reported a…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Effects of Personality and Context on Recovery From Coronary Artery Bypass
A completed NHLBI-sponsored trial update examining how personality and context influence recovery after coronary artery bypass graft surgery…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Schema Focused Therapy for Chronic Depression [NA]
A completed clinical trial evaluating Schema Focused Therapy for chronic major depressive disorder.
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CLINICAL_TRIALS research · 2016-03-16Clinical Trial Update: Impact of Sleep Disordered Breathing in Older Adults
A completed clinical trial evaluating the impact of sleep-disordered breathing on older adults and its potential associations with cardiovas…
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CLINICAL_TRIALS trial_result · 2016-03-15Clinical Trial Update: Study of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Therapy [Phase 3]
A Phase 3 trial evaluated brexpiprazole as an adjunctive treatment for irritability in adults with major depressive disorder who did not ade…
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FDA approval · 2016-03-14FDA Approved: SERTRALINE HYDROCHLORIDE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for sertraline hydrochloride from Aurobindo Pharma Limited, enabling the commercialization of a gene…
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FDA approval · 2016-03-14FDA Approved: FLUOXETINE — Supplemental Application (QUALLENT PHARMACEUTICALS HEALTH LLC)
The FDA approved a supplemental application from Quallent Pharmaceuticals Health LLC to market fluoxetine hydrochloride as a generic product…
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CLINICAL_TRIALS research · 2016-03-14Clinical Trial Update: Serotonin-norepinephrine Reuptake Inhibitors and Acute Kidney Injury
A completed observational study update evaluating possible links between serotonin-norepinephrine reuptake inhibitors and acute kidney injur…
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Collaborative Care for Depressed Elderly in Korea [NA]
A completed clinical trial in Korea studying collaborative care approaches for depression in elderly patients.
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Health Care Management for the Elderly in Community Through Screening [NA]
This clinical trial update notes completion of a study on elderly community health management through screening, focusing on major depressiv…
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Effect of Depressin Screening and Care Program at Community Health Center [NA]
A completed clinical trial evaluating the Depressin screening and care program for depression in elderly adults at community health centers.
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Effects of Adding Motivational Interviewing to Antidepressant Treatment for Hispanic Adults With Depression [NA]
Clinical trial evaluating adding motivational interviewing to antidepressant treatment in Hispanic adults with depression has completed; res…
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial. [Phase 2]
Phase 2 randomized trial comparing aromatase inhibition versus testosterone in older men with low testosterone; results completed with poste…
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FDA approval · 2016-03-08FDA Approved: QUETIAPINE FUMARATE — Original Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved Quetiapine Fumarate as a generic tablet under Original Application (ANDA 202674) for Unichem Pharmaceuticals (USA), Inc.
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Omega-3 Supplementation and Depression Clinical Trial [NA]
A completed clinical trial conducted by the University of Nairobi evaluated omega-3 fatty acid supplementation for depressive symptoms, with…
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Omega-3 and Therapy Study for Depression [Phase 1]
Phase 1 clinical trial evaluating omega-3 fatty acids as an adjunct to therapy for depression has completed.
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: How to Cope With Anxiety and Depression. A Randomized Controlled Trial. [NA]
This randomized controlled trial evaluates a coping intervention for anxiety and depression and reports outcomes related to mood and self-ef…
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: HPA Axis Activity Due To Early Traumatic Stress and Metabolic Symptoms [NA]
This clinical trial update describes a completed study examining HPA axis activity and metabolic symptoms associated with early traumatic st…
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care [Phase 3]
This document provides an update on a Phase 3 randomized trial comparing cognitive behavioral therapy (CBT) to a return-to-work intervention…
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: COPES Phase I Randomized Controlled Trial of Treatment For Distress in Heart Disease Patients [NA]
Phase I randomized controlled trial evaluating a treatment for distress in heart disease patients; results were posted in 2016.