Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-04-07Clinical Trial Update: Addressing Mental Health in African American Job Training Adolescents and Young Adults [Phase 1]
Phase 1 clinical trial update investigating depression interventions for African American adolescents and young adults in job-training progr…
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CLINICAL_TRIALS trial_result · 2016-04-07Clinical Trial Update: Short-term Cognitive Training in Late-life Depression [NA]
The clinical trial evaluating short-term cognitive training for late-life depression has been terminated.
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Venlafaxine PK Following Bariatric Surgery [Phase 4]
Phase 4 study evaluating how bariatric surgery affects the pharmacokinetics of venlafaxine has completed, assessing changes in drug exposure…
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffering Capacity [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial evaluating malic acid 1% on drug-induced xerostomia with evaluation of salivary mucins and buffering capacity…
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: Correlation Between Sagittal Balance of the Spine and Psychopathological Profile
A terminated clinical trial from University Hospital Strasbourg investigated whether sagittal spine alignment correlates with psychopatholog…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Screening of Adolescent Mental Suffering [NA]
Clinical trial registry entry indicating completion of a study on screening for depression in adolescents using self-report questionnaires.
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CLINICAL_TRIALS trial_result · 2016-04-01Clinical Trial Update: Role of Exercise in Depression in Middle Aged and Older Adults [NA]
A completed clinical trial from Indiana University evaluated whether exercise affects depression in middle-aged and older adults.
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FDA approval · 2016-03-31FDA Approved: ESCITALOPRAM — Original Application (Macleods Pharmaceuticals Limited)
FDA approved the original application for escitalopram from Macleods Pharmaceuticals Limited (generic escitalopram).
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Study Using Pregnenolone to Treat Bipolar Depression [Phase 4]
A Phase 4 clinical trial evaluating pregnenolone for the treatment of bipolar depression has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-03-30Clinical Trial Update: The Integrated Care Model for Homeless Mothers [NA]
The completed clinical trial evaluated an Integrated Care Model for homeless mothers with depression. The update notes the completion status…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms [Phase 3]
This update reports Phase 3 results for brexpiprazole as an adjunctive treatment to antidepressants in adults with major depressive disorder…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: Efficacy of an Exercise Intervention to Decrease Depressive Symptoms in Veterans With Hepatitis C [NA]
A completed clinical trial evaluated whether an exercise program reduces depressive symptoms in veterans with hepatitis C.
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work Environment [Phase 3]
This Phase 3 trial evaluated brexpiprazole as an adjunctive treatment for adults with major depressive disorder in a school or work environm…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: B Vitamins in MTHFR Positive Patients With Major Depression: A Post Hoc Analysis of Findings [Phase 4]
A Phase 4 post-hoc analysis reports findings on the use of B vitamins in patients with major depressive disorder who are MTHFR positive.
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: Safety and Efficacy of EVT 101 in Treatment-Resistant Depression [Phase 2]
Phase 2 trial of EVT 101 for treatment-resistant depression was terminated; the update does not report efficacy results.
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: Internet-delivered Psychotherapy for Depression [NA]
This clinical trial evaluated internet-delivered psychotherapy for depression and has been terminated; results were posted on 2016-03-28.
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Intervention for Veterans With Depression, Substance Disorder, and Trauma [NA]
Completed VA-sponsored trial evaluating an intervention for veterans with depression, substance use disorders, and trauma; results were post…
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FDA approval · 2016-03-23FDA Approved: ESCITALOPRAM OXALATE — Supplemental Application (Quallent Pharmaceuticals Health LLC)
FDA approved a supplemental application for escitalopram oxalate from Quallent Pharmaceuticals Health LLC.
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Research Study for Major Depressive Disorder: Investigation of Glutamate Medications [Phase 4]
A Phase 4 clinical trial investigating glutamate-targeting medications for major depressive disorder has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Return to Work: Promoting Health and Productivity in Workers With Common Mental Disorders [NA]
This document reports the completion of a clinical trial evaluating a return-to-work intervention for workers with common mental disorders, …
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CLINICAL_TRIALS trial_result · 2016-03-18Clinical Trial Update: Add-On Study of MSI-195 (S-Adenosyl-L-Methionine, SAMe) for Patients With Major Depressive Disorder (MDD) [Phase 2]
A Phase 2 add-on trial of MSI-195 (S-adenosyl-L-methionine) for Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2016-03-18Clinical Trial Update: Effectiveness of Parenting Programs on Child Development and Maternal Well-being in Rural Uganda [NA]
This clinical trial update reports that a study evaluating the effectiveness of parenting programs on child development and maternal well-be…
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CLINICAL_TRIALS trial_result · 2016-03-18Clinical Trial Update: Brief Behavioral Activation Treatment for Depression With Inpatients [NA]
A completed study of Brief Behavioral Activation Treatment for Depression With Inpatients (NCT02712918) sponsored by Lovisenberg Diakonale H…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Efficacy and Safety of GLYX-13 in Subjects With Inadequate/Partial Response to Antidepressants [Phase 2]
This Phase 2 trial evaluated the efficacy and safety of GLYX-13 in adults with major depressive disorder who had an inadequate response to a…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Buprenorphine for Late-Life Treatment Resistant Depression [Phase 2]
A Phase 2 clinical trial evaluating buprenorphine for late-life treatment-resistant depression has completed. The results were posted in 201…