Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-12Clinical Trial Update: Rapid Antidepressant Effects of Ketamine in Major Depression [Phase 1, Phase 2]
Phase 1/Phase 2 trial investigating rapid antidepressant effects of ketamine in major depression completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Effectiveness of a Mobile Technology Intervention for the Treatment of Depression [Phase 3]
Phase 3 clinical trial evaluating a mobile technology intervention for treating depression with data including depression and diabetes comor…
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Negative Valence Brain Targets and Predictors of Anxiety and Depression Treatment [Phase 4]
Phase 4 clinical trial update investigating negative valence brain targets and predictors of anxiety and depression treatment for internaliz…
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive Impairment [Phase 4]
Phase 4 trial update evaluating duloxetine for cognition improvement in mild cognitive impairment with comorbid depression has been complete…
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CLINICAL_TRIALS trial_result · 2018-10-05Clinical Trial Update: Investigation on the Value of Bilateral Index (BIS) Monitoring for Magnetic Seizure Versus Electroconvulsive Therapy
A completed clinical trial investigating the value of Bilateral Index (BIS) monitoring for magnetic seizure versus electroconvulsive therapy…
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CLINICAL_TRIALS trial_result · 2018-10-04Clinical Trial Update: rTMS for PTSD Comorbid With Major Depressive Disorder [NA]
A completed clinical trial evaluating repetitive transcranial magnetic stimulation (rTMS) for PTSD with comorbid major depressive disorder.
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FDA approval · 2018-09-28FDA Approved: QUETIAPINE EXTENDED-RELEASE — Original Application (AlignScience Pharma Inc.)
FDA approved AlignScience Pharma Inc.'s generic extended-release quetiapine tablets (ANDA 209497). The approval enables a generic version of…
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CLINICAL_TRIALS trial_result · 2018-09-27Clinical Trial Update: Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study) [Phase 4]
Phase 4 clinical trial update on depressed mood improvement with nicotine dosing in adults with major depressive disorder; study completed a…
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CLINICAL_TRIALS trial_result · 2018-09-25Clinical Trial Update: Tapering Off Antidepressants [NA]
A terminated clinical trial from Emory University investigating tapering off antidepressants in patients with major depressive disorder and …
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Improving Therapeutic Learning in Depression: Proof of Concept [Phase 2]
Phase 2 clinical trial update exploring therapeutic learning approaches for Major Depressive Disorder; study completed with results posted i…
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CLINICAL_TRIALS trial_result · 2018-09-18Clinical Trial Update: Zaleplon in HIV Patients With Depression [Phase 2]
Phase 2 trial evaluating zaleplon in HIV patients with depression has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) [Phase 3]
Phase 3 trial update on the safety and tolerability of oral OPC-34712 as an adjunctive therapy for adults with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2018-09-14Clinical Trial Update: Ketamine as a Rapidly-Acting Antidepressant in Depressed Emergency Department Patients [Phase 2]
Phase 2 clinical trial investigating ketamine as a rapidly-acting antidepressant in depressed emergency department patients has completed wi…
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Ketamine Co-induction for Patients With Major Depressive Disorder [Phase 4]
Clinical trial update for ketamine co-induction in major depressive disorder (Phase 4).
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CLINICAL_TRIALS trial_result · 2018-09-12Clinical Trial Update: Transcranial Direct Current Stimulation (tDCS) as an add-on Therapy for Treatment of Major Depressive Disorder. (DEPTDCS2014) [Phase 2, Phase 3]
Clinical trial update for transcranial direct current stimulation (tDCS) as an add-on therapy for major depressive disorder across Phase 2 a…
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CLINICAL_TRIALS trial_result · 2018-09-10Clinical Trial Update: Antidepressant Mechanisms of Transcranial Magnetic Stimulation [NA]
Clinical trial update on mechanisms of transcranial magnetic stimulation for depression; study completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-07Clinical Trial Update: Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder [Phase 2]
Phase 2 clinical trial investigating naltrexone plus ketamine for rapid treatment of major depressive disorder and alcohol use disorder comp…
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CLINICAL_TRIALS trial_result · 2018-09-07Clinical Trial Update: Lexapro®'s Efficacy After Dose Escalation in Remission Study [Phase 4]
Phase 4 trial update evaluating efficacy of Lexapro after dose escalation in remission for Major Depressive Disorder.
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CLINICAL_TRIALS trial_result · 2018-09-07Clinical Trial Update: Effect of Lactobacillus Plantarum 299v Supplementation on Major Depression Treatment [Phase 2]
Phase 2 trial evaluating Lactobacillus Plantarum 299v supplementation as an adjunct in major depression treatment has completed.
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CLINICAL_TRIALS trial_result · 2018-09-04Clinical Trial Update: Monocentric Pilot Study, for a Randomized, Crossover, Blinded Trial: Comparison of the Therapeutic Efficacy of Low Frequency Repeated Transcranial Magnetic Stimulation on Cortical Area 9 Compared to Brodmann Area 46 in the Treatment of Depressive Disorders. [Phase 2]
Phase 2 randomized, crossover, blinded trial comparing low-frequency rTMS over cortical area 9 vs Brodmann area 46 for resistant depressive …
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Depression & Other Neuropsychiatric Symptoms After Traumatic Brain Injury (TBI) [Phase 2, Phase 3]
Phase 2/3 clinical trial update on repetitive transcranial magnetic stimulation (rTMS) for depression and other neuropsychiatric symptoms af…
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CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress [Phase 3]
Phase 3 study evaluating fixed-dose brexpiprazole as adjunctive therapy in adults with major depressive disorder with and without anxious di…
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CLINICAL_TRIALS trial_result · 2018-08-20Clinical Trial Update: The Depression in Alzheimer's Disease Study (DIADS) [Phase 4]
A Phase 4 clinical trial update for the Depression in Alzheimer's Disease Study (DIADS) has completed; the study investigates depression in …
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CLINICAL_TRIALS trial_result · 2018-08-20Clinical Trial Update: Transcranial Alternating Current Stimulation for Major Depressive Disorder [NA]
Clinical trial update completed study on transcranial alternating current stimulation for major depressive disorder; results posted in 2018.
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FDA label_change · 2018-08-13FDA Approved: VENLAFAXINE HYDROCHLORIDE — Supplemental Application (Macleods Pharmaceuticals Limited)
FDA approved a supplemental application for venlafaxine hydrochloride filed by Macleods Pharmaceuticals Limited. The approval is associated …