Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-11-14Clinical Trial Update: Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression [Phase 4]
Phase 4 clinical trial update on improving effectiveness of electroconvulsive therapy in severe depression completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-13Clinical Trial Update: A Study to Evaluate the Effect of Food on LY2216684 [Phase 1]
Phase 1 trial updating the effect of food on LY2216684 in depressive disorders has concluded with results posted.
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FDA approval · 2018-11-09FDA Approved: NORPRAMIN — Supplemental Application (Validus Pharmaceuticals LLC)
The FDA has approved a supplemental application for Norpramin (desipramine hydrochloride) submitted by Validus Pharmaceuticals LLC.
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CLINICAL_TRIALS research · 2018-11-08Clinical Trial Update: Endogenous Opioid Activity and Affective State in Insulin Resistant Women [Phase 4]
Phase 4 clinical trial investigating endogenous opioid activity and affective state in women with insulin resistance, with completion and po…
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CLINICAL_TRIALS trial_result · 2018-11-05Clinical Trial Update: Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans [NA]
A completed clinical trial evaluating Behavioral Activation for PTSD and Depression in OIF/OEF veterans; results posted in 2018.
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FDA approval · 2018-10-31FDA Approved: BUPROPION HYDROCHLORIDE — Original Application (Accord Healthcare Inc.)
FDA approved Accord Healthcare's original application for a generic bupropion hydrochloride product. The approval supports use for major dep…
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CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: A Multicenter, Relapse Prevention Study With Levomilnacipran Extended Release (ER) in Participants With Major Depressive Disorder [Phase 4]
Phase 4 clinical trial update on relapse prevention with levomilnacipran ER in adults with major depressive disorder; results posted after c…
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CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: IntelliCare: Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM) [NA]
Clinical trial completion for IntelliCare AIM, an AI-driven mobile intervention for depression and anxiety, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: Mobile Technology to Engage and Link Patients and Providers in Antidepressant Treatment (MedLink) [NA]
A completed clinical trial investigating mobile technology to engage patients and providers in antidepressant treatment for depression; resu…
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CLINICAL_TRIALS trial_result · 2018-10-29Clinical Trial Update: Online Peer Networked Collaborative Learning for Managing Depressive Symptoms [NA]
A completed clinical trial investigating an online peer networked collaborative learning approach for managing depressive symptoms.
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: A Study to Evaluate the Effect of Genotype on LY2216684 [Phase 1]
Phase 1 study evaluating the effect of genotype on LY2216684 completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: A Study of LY2216684 in Participants With Major Depression Disorder [Phase 3]
Phase 3 clinical trial update for LY2216684 in participants with Major Depressive Disorder; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: Tele-IPT for HIV-Infected Rural Persons [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Tele-IPT for HIV-infected rural individuals, including HIV/AIDS and depression conditions; study complet…
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CLINICAL_TRIALS trial_result · 2018-10-23Clinical Trial Update: A Study of LY2216684 in Healthy Females [Phase 1]
Phase 1 trial of LY2216684 in healthy females completed; study related to depressive disorder conditions (Major Depressive Disorder).
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CLINICAL_TRIALS trial_result · 2018-10-23Clinical Trial Update: A Study of LY2216684 in Major Depressive Disorder in Patients Taking Selective Serotonin Reuptake Inhibitors [Phase 1]
A Phase 1 trial evaluating LY2216684 in adults with major depressive disorder who are taking SSRIs has completed, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: A Study to Measure if There is Any Difference in How the Body Breaks Down or Inactivates Either Fluoxetine or LY2216684 When Both of These Medicines Are Given Together. [Phase 1]
A Phase 1 study evaluated whether co-administration of fluoxetine and LY2216684 alters their pharmacokinetics, indicating potential drug–dru…
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: A Study of LY2216684 in Participants With Impaired Hepatic Function [Phase 1]
Phase 1 study of LY2216684 in participants with impaired hepatic function has completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: A Pharmacokinetic Study on the Effect of LY2216684 on the Active Metabolite of Clopidogrel [Phase 1]
Phase 1 pharmacokinetic study assessing the effect of LY2216684 on the active metabolite of clopidogrel; completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: A Study of LY2216684 and Digoxin in Healthy Subjects [Phase 1]
Phase 1 trial update on LY2216684 and digoxin in healthy subjects for Major Depressive Disorder; completed with results posted.
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FDA approval · 2018-10-19FDA Approved: TRINTELLIX — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
The FDA approved a supplemental application for vortioxetine (Trintellix) submitted by Takeda Pharmaceuticals America. The approval updates …
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CLINICAL_TRIALS trial_result · 2018-10-19Clinical Trial Update: A Study of LY2216684 and Warfarin in Healthy Subjects [Phase 1]
A Phase 1 trial assessed the interaction between Eli Lilly's LY2216684 and Warfarin in healthy subjects. The study lists Major Depressive Di…
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CLINICAL_TRIALS trial_result · 2018-10-19Clinical Trial Update: A Pharmacokinetic Study of the Coadministration of LY2216684 With Sertraline [Phase 1]
Phase 1 pharmacokinetic study evaluating coadministration of LY2216684 with sertraline in adults with major depressive disorder.
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CLINICAL_TRIALS trial_result · 2018-10-16Clinical Trial Update: Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms [Phase 3]
Phase 3 trial update evaluating sequential fluoxetine use for smokers with elevated depressive symptoms; study completed with posted results…
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FDA approval · 2018-10-16FDA Approved: BUPROPION HYDROCHLORIDE SR — Original Application (Slate Run Pharmaceuticals, LLC)
FDA approves the original generic application for Bupropion Hydrochloride SR, enabling Slate Run Pharmaceuticals to market a generic sustain…
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CLINICAL_TRIALS trial_result · 2018-10-15Clinical Trial Update: Positron Emission Tomography Assessment of Ketamine Binding of the Serotonin Transporter [Phase 2]
Phase 2 trial update assessing ketamine binding to the serotonin transporter using positron emission tomography in depression.