Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Readiness and Progress in Emotion Regulation Therapy [NA]
ClinicalTrials.gov entry indicates that Emotion Regulation Therapy is currently recruiting participants for a study addressing rumination, w…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care [NA]
Brigham and Women's Hospital is sponsoring a clinical trial evaluating acute psychiatric care at home for lower-risk patients who would othe…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Addressing Depression and Positive Parenting Techniques (ADAPT) [NA]
Clinical trial ADAPT evaluating depression and positive parenting techniques has completed.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: ACT-based Parenting Program for Caregivers of Children With Hearing Loss Post-cochlear: A Pilot Randomised Controlled Trial [NA]
This clinical trial update describes a pilot randomized controlled trial of an ACT-based parenting program for caregivers of children with h…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD) [NA]
This document notes an ongoing clinical trial evaluating Transcranial Electric Stimulation Therapy (TEST) for treatment-resistant depression…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Activity and Recreation in Communities for Health [NA]
A Rush University Medical Center clinical trial update describes a study on Depression titled 'Activity and Recreation in Communities for He…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: ipRGC as a Potential Biomarker for Predicting Transcranial Magnetic Stimulation Treatment Response in Major Depressive Disorder [NA]
A clinical trial is evaluating intrinsically photosensitive retinal ganglion cells (ipRGCs) as a biomarker to predict response to transcrani…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease [EARLY_Phase 1]
Phase 1 study from Johns Hopkins is evaluating psilocybin for depressive symptoms in people with mild cognitive impairment or early Alzheime…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: CAPABLE Transplant [NA]
Status update for the CAPABLE Transplant trial sponsored by Johns Hopkins University; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Project HOPEFUL: A PN-RCT With Implementation Science [NA]
A clinical trial update for Project HOPEFUL, a PN-RCT with implementation science, currently recruiting older adults with mental health conc…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure Therapy [NA]
A clinical trial investigating the combination of electroconvulsive therapy and magnetic seizure therapy for major depressive disorder is cu…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Virtual Reality to Reduce Pre-procedure Anxiety Prior ECT [NA]
Researchers are evaluating whether virtual reality can reduce pre-procedure anxiety in patients undergoing electroconvulsive therapy. The st…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application [NA]
Recruitment is ongoing for a study evaluating a smartphone-based tool to help physicians manage depression on a day-to-day basis. The sponso…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Transcranial Electrical Stimulation for Comorbid Depression and Chronic Pain [NA]
A clinical trial update describes transcranial electrical stimulation being evaluated for comorbid depression and chronic pain. The study st…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder [Phase 2]
Phase 2 clinical trial update evaluating psilocybin for major depressive disorder with co-occurring alcohol use disorder, sponsored by Johns…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: The RAFT ECT Study [NA]
The RAFT ECT study, sponsored by The George Institute, studying treatment for major depressive disorder, has completed.
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD) [Phase 1]
Phase 1 PET imaging study to assess cyclooxygenase activity in adults with major depressive disorder. The study investigates COX-related bra…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Treatment Response In ECT Patients
An update on a clinical trial evaluating treatment response to electroconvulsive therapy in patients with major depressive disorder and bipo…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: African Youth in Mind (Y-MIND) - Pilot Feasibility Trial of a Brief Psychological Intervention for Young People With Depression in Zimbabwe [NA]
Update on a pilot feasibility trial (Y-MIND) evaluating a brief psychological intervention for depression among young people in Zimbabwe; th…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: CBT+ for Depression [NA]
The study evaluating CBT+ for Major Depressive Disorder has completed; the update does not include results.
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive Disorder [NA]
A recruiting clinical trial evaluating social cognition, memory, and executive functions in individuals with bipolar disorder and major depr…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: A Phase 3 Trial of MM120 for Major Depressive Disorder (Emerge) [Phase 3]
MM120's Phase 3 trial for major depressive disorder is currently active but not recruiting. The trial is sponsored by Definium Therapeutics …
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Self-Help Plus for Distress in University Students [NA]
A clinical trial update indicates the University of Padova is recruiting for a study evaluating Self-Help Plus to reduce distress and improv…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Preventing Depression of Chinese American Adolescents by RRE [NA]
A Northeastern University-sponsored clinical trial is currently recruiting to prevent depression in Chinese American adolescents with subcli…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in Depression [NA]
A brain stimulation study in depression examines the causal role of the rostromedial prefrontal cortex in positive savoring. The trial is cu…