Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children [NA]
Clinical trial update describing the STAIR trauma-focused parenting intervention being adapted for military-connected mothers and their chil…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: The COMParing App Support Strategies Study [NA]
A clinical trial update for the COMParing App Support Strategies Study by the University of Wisconsin–Madison, currently recruiting to evalu…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: intErnet-based iNterventions FOR Cardiac arrEst suRvivors [NA]
A clinical trial is currently recruiting to test internet-based interventions for survivors of cardiac arrest, focusing on cognitive impairm…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Integrating Digital Phenotypes and AI-Driven Cognitive-Behavioral Therapy: Advancing Precision Medicine in Depression Through Digital Medicine [NA]
This clinical trial update describes a study integrating digital phenotyping and AI-driven cognitive-behavioral therapy to advance precision…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Transcranial Direct Current Stimulation for Depression [NA]
A clinical trial evaluating transcranial direct current stimulation as a treatment for depression is listed as not yet recruiting.
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CLINICAL_TRIALS other · 2026-03-30Clinical Trial Update: Compassion Meditation vs. Health Education for Veterans [Phase 2]
Phase 2 trial comparing compassion meditation to health education for veterans with chronic pain, posttraumatic stress disorder, and depress…
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FDA approval · 2026-03-27FDA Approved: ESCITALOPRAM — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' supplemental application for a generic escitalopram product (ANDA 078169).
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine [Phase 2]
A Phase 2 study evaluating different doses of BI 1569912 in adults with major depressive disorder who are taking antidepressants has complet…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Minocycline as Adjunctive Treatment for Treatment Resistant Depression [Phase 3]
A Phase 3 clinical trial evaluating minocycline as an adjunctive treatment for treatment-resistant depression has completed.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Comparing Effect and Change Processes in Cognitive Behavioral Therapy and Emotion-Focused Therapy for Depression [NA]
Completed clinical trial comparing effect and change processes in Cognitive Behavioral Therapy and Emotion-Focused Therapy for Depression. T…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Multivariate Approach to the Numerical Assessment of Cortical - Autonomic - VAscular Dynamic Interplay [NA]
Clinical trial NCT06294119 is currently recruiting to evaluate a multivariate approach for numerical assessment of cortical-autonomic-vascul…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Appalachian Mind Health Initiative [NA]
The Appalachian Mind Health Initiative clinical trial for Major Depressive Disorder has completed.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Alexithymia Intervention for Suicide [Phase 1]
Phase 1 trial of an alexithymia intervention for suicide risk was terminated.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: SMILE Trial - Imaging Sub-Study
This clinical trial update reports the completion of the imaging sub-study within the SMILE trial for Major Depressive Disorder, sponsored b…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality [NA]
This clinical trial update reports on a study examining brain changes during social reward-based psychotherapy for mid- and late-life suicid…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Neurobiology of Suicide [Phase 2]
A Phase 2 clinical trial update on the neurobiology of suicide, sponsored by NIMH, currently recruiting participants including healthy volun…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Electrophysiological Markers of Antidepressants in Major Depressive Disorder [NA]
A clinical trial evaluating electrophysiological markers of antidepressants in Major Depressive Disorder is listed, with recruitment not yet…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory Depression [Phase 1, Phase 2]
An update on a Phase 1/2 clinical trial of psilocybin derived from Psilocybe cubensis mushrooms, with or without fluoxetine, for refractory …
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FDA approval · 2026-03-26FDA Approved: PAROXETINE — Supplemental Application (Alembic Pharmaceuticals Inc.)
The FDA approved Alembic Pharmaceuticals Inc.'s supplemental application for paroxetine (generic). This marks approval of a generic paroxeti…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder
This ClinicalTrials.gov update describes a recruiting study investigating gender differences in depression severity, gender-sensitive sympto…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: A Graphene Far-infrared Intervention Study of Cognitive Status in Older Adults [NA]
Completed clinical trial evaluating a graphene-based far-infrared intervention on cognitive status in older adults, including individuals wi…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Positive Affect Treatment for Spanish-Speaking Individuals [NA]
This clinical trial update describes a study testing Positive Affect Treatment for adults with anhedonia and depression, currently active bu…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Validation of Accexible as a Tool for Screening and Monitoring Depression.
The document summarizes a completed clinical trial validating Accexible as a tool for screening and monitoring Major Depressive Disorder.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: SUBDIMA: Subclinical Depression in Acute Myocardial Infarction (SUBDIMA25) [NA]
Clinical trial SUBDIMA25 is investigating subclinical depression in patients with acute myocardial infarction; the study is currently recrui…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Intradermal Acupuncture for Assisting SSRI Dose Reduction in Major Depressive Disorder [NA]
A clinical trial evaluating intradermal acupuncture as an adjunct to help taper SSRI doses in adults with Major Depressive Disorder.