Major Depressive Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Psilocybin for Major Depressive Disorder (MDD) [Phase 3]
Phase 3 trial update for psilocybin in major depressive disorder. The study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
This clinical trial update outlines a pilot study using electrobulbogram (EBG), fMRI, and diffusion-weighted imaging to explore central brai…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder [Phase 1]
Clinical Trial Update describing a Phase 1 study evaluating neuropharmacologic imaging and biomarker assessments of response to acute- and r…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: MindfulCityU-- A Mindfulness Mobile Application for Promoting University Students' Mental Health [NA]
A clinical trial is evaluating a mindfulness mobile app, MindfulCityU, to improve mental health and reduce depressive symptoms among univers…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression [Phase 2]
A Phase 2 clinical trial evaluating the effectiveness of DT-101 in patients with Major Depressive Disorder is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
A prospective observational study examining how sociodemographic factors, blood-based biomarkers, and psychiatric symptoms relate across sev…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET [Phase 1]
A Phase 1 clinical trial update from NIMH evaluating the PET radiotracer [18F]PF-06445974 to image PDE4B in individuals with major depressiv…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Nebulized Ketamine for the Treatment of Major Depressive Disorder [Phase 3]
A Phase 3 clinical trial is evaluating nebulized ketamine for major depressive disorder and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Mindfulness-Based fMRI Neurofeedback for Depression [NA]
Columbia University is conducting a trial to evaluate mindfulness-based fMRI neurofeedback as a treatment for depression in adolescence, wit…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders [Phase 2]
Clinical trial update for a Phase 2 study by the National Institute of Mental Health (NIMH) exploring neuro-cognitive correlates of pediatri…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Efficacy of Narrative Therapy for Older People With Depression [NA]
The document notes that a clinical trial evaluating narrative therapy for depression in older adults is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Mobile Application Mindfulness [NA]
A University of South Florida-sponsored clinical trial is evaluating a mindfulness mobile app for stress, anxiety, depression, and psycholog…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Characterization and Treatment of Adolescent Depression
This National Institute of Mental Health-sponsored study is characterizing and treating adolescent depression and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Enhancing Slow Wave Sleep in Depression [NA]
A clinical trial investigating enhancement of slow-wave sleep as a treatment strategy for major depressive disorder is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) [Phase 3]
A Phase 3 clinical trial update notes ongoing recruitment for evaluating the safety and tolerability of NBI-1065845 as an adjunctive treatme…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: eBehandling - Health and Work for Patients in Specialist Mental Health Care [NA]
A recruiting clinical trial named eBehandling aims to improve health and work outcomes for patients in specialist mental health care, focusi…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: E-Mindfulness Approaches for Living After Breast Cancer [Phase 3]
This document describes a Phase 3 clinical trial called E-Mindfulness Approaches for Living After Breast Cancer, sponsored by NRG Oncology, …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Virtual Intervention for Behavioral Health in Emerging Adults; "VIBE in the Parks" [NA]
A clinical trial update for a virtual behavioral health intervention called 'VIBE in the Parks' targeting anxiety and depression in emerging…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: IMPlementation of Evidence Based Facility and Community Interventions to Reduce the Treatment Gap for depRESSion [NA]
A clinical trial is currently recruiting to implement evidence-based facility and community interventions aimed at reducing the treatment ga…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study [Phase 2, Phase 3]
A non-inferiority study evaluating electro-magnetic convulsive therapies for major depressive disorder and bipolar depression is ongoing in …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Playback Theatre Program for Adolescents and Youth [NA]
Sponsor City University of Hong Kong reports a recruiting clinical trial evaluating a playback theatre program for adolescents and youth wit…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)
The record notes the completion of a clinical trial in adults with major depressive disorder and anhedonia who had an inadequate response to…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Stony Brook Medicine Anti-Inflammatory Trial [Phase 4]
Stony Brook University announced an anti-inflammatory trial for Major Depressive Disorder in Phase 4. The study status is NOT_YET_RECRUITING…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Digital Intervention for Post-Stroke Depression and Executive Dysfunction [Phase 2]
Phase 2 clinical trial of a digital intervention for post-stroke depression and executive dysfunction is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Neural and Psychiatric Consequences of Cannabis Use in Adolescents [NA]
A University of Miami-sponsored clinical trial is recruiting adolescents to study the neural and psychiatric consequences of cannabis use, i…