Catalyst Wire Dossier Catalyst Wire Dossier
CLINICAL_TRIALS research · 2026-04-24

Clinical Trial Update: [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET [Phase 1]

View source ↗

Summary

A Phase 1 clinical trial update from NIMH evaluating the PET radiotracer [18F]PF-06445974 to image PDE4B in individuals with major depressive disorder; recruitm…

Upgrade for the full analysis, importance score, and drug timeline.

Diseases / indications

Drugs mentioned

  • [18F]PF-06445974 (PF-06445974)

Snippet

Sponsor: National Institute of Mental Health (NIMH) | Conditions: Depression | Phase 1 | Status: RECRUITING