Lynch Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Dendritic Cell Vaccination in Patients With Lynch Syndrome or Colorectal Cancer With MSI [Phase 1, Phase 2]
This update describes an ongoing phase 1/2 clinical trial of a dendritic cell vaccine in patients with Lynch syndrome or colorectal cancer w…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome
This completed clinical trial investigated how frequently precursors to endometrial cancer occur in individuals with Lynch syndrome.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Predictive Value of PREMM5, MMRpredict, and Universal Tumor Screening for Lynch Syndrome in Vietnam
This clinical trial evaluates the predictive value of PREMM5, MMRpredict, and universal tumor screening for Lynch syndrome in Vietnam, with …
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland
This update describes a Swiss clinical trial at the University of Basel evaluating cascade genetic testing for hereditary breast and ovarian…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer [EARLY_Phase 1]
Early-phase trial update shows termination of a tislelizumab study for recurrent mismatch repair-deficient endometrial cancer.
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Lynch Syndrome Integrative Epidemiology and Genetics
A clinical trial sponsored by the University of Colorado, Denver is studying patients with Lynch syndrome and is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: DYNAMICS-LYNCH：DNA Methylation Analysis in Stool for Screening of Lynch Syndrome-Associated Colorectal Cancer
This clinical trial investigates stool DNA methylation analysis as a screening tool for Lynch syndrome-associated colorectal cancer; the stu…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome [Phase 2]
Phase 2 clinical trial update on using mesalamine to prevent colorectal cancer in Lynch syndrome; the study is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Video Capsule Examination in Patients With Lynch Syndrome [NA]
Status update for NCT06712095 shows recruitment underway for a study assessing video capsule examination in patients with Lynch syndrome and…
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: Prostate Cancer Genetic Risk Evaluation and Screening Study
Massachusetts General Hospital's clinical trial update describes a recruiting study to evaluate genetic risk and screening for prostate canc…
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CLINICAL_TRIALS withdrawal · 2024-08-14Clinical Trial Update: Biomarkers in Samples From Patients With Endometrial Cancer
This clinical trial update reports that the biomarker study in endometrial cancer samples sponsored by Gynecologic Oncology Group has been w…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Registry for Women Who Are At Risk Or May Have Lynch Syndrome
A completed registry study examining women who are at risk for or may have Lynch syndrome (hereditary nonpolyposis colorectal cancer).
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: EC_ItaLynch: Mainstreaming the Diagnosis of Lynch Syndrome
This clinical trial evaluates a streamlined approach to diagnosing Lynch syndrome in the context of Lynch syndrome and endometrial cancer. T…
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CLINICAL_TRIALS guidance · 2024-07-09Clinical Trial Update: Direct Information to At-risk Relatives [NA]
Clinical trial update about providing direct information to at-risk relatives for hereditary cancer syndromes.
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy [Phase 2]
Phase 2 trial evaluating Nivolumab to prevent colon adenomas in participants with Lynch syndrome and a history of partial colectomy. The stu…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome
PSYLIVED studies the psychological impacts of living with inherited colorectal cancer predisposition syndromes and is currently recruiting. …
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: Pancreatic Cancer Early Detection Program
A clinical trial update for White Plains Hospital describes an active, not currently recruiting program focused on early detection of pancre…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE) [Phase 2]
Phase 2 clinical trial update evaluating omega-3 fatty acids for colorectal cancer prevention in patients with Lynch syndrome.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome Patients [Phase 3]
Phase 3 clinical trial update for a PD-1 antibody aimed at preventing adenomatous polyps and second primary tumors in Lynch syndrome patient…
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CLINICAL_TRIALS research · 2019-02-07Clinical Trial Update: Genetic Risk: Whether, When, and How to Tell Adolescents
A completed Johns Hopkins clinical trial examining when and how to communicate genetic risk information to adolescents for Huntington's dise…
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CLINICAL_TRIALS research · 2018-06-28Clinical Trial Update: Ohio Colorectal Cancer Prevention Initiative [NA]
This is a clinical trial update for the Ohio Colorectal Cancer Prevention Initiative, investigating Lynch syndrome and colorectal cancer. Th…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: High Definition White-Light Colonoscopy vs. Chromoendoscopy for Surveillance of Lynch Syndrome. [NA]
A completed clinical trial comparing high-definition white-light colonoscopy with chromoendoscopy for surveillance in patients with Lynch sy…
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CLINICAL_TRIALS research · 2017-10-06Clinical Trial Update: The GEOLynch Cohort Study
The GEOLynch Cohort Study, sponsored by Wageningen University, is currently recruiting to investigate Lynch Syndrome-associated neoplasms.
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CLINICAL_TRIALS research · 2017-08-02Clinical Trial Update: Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer
The trial from Vanderbilt University Medical Center completed and collected information from patients and family members with hereditary col…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: I-Scan For Colon Polyp Detection In HNPCC [NA]
Completed clinical trial evaluating I-Scan imaging for colon polyp detection in patients with Lynch syndrome.