Lynch Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural Environment [NA]
This ClinicalTrials.gov entry outlines a strategy-focused study for managing patients with hereditary cancer syndromes, including BRCA1-asso…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Identifying and Caring for Individuals With Inherited Cancer Syndrome [NA]
The study is currently recruiting and aims to identify and care for people with inherited cancer syndromes, including BRCA1/2-associated her…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study Aiming to Test Whether Non-invasive Liquid Biopsies Can Safely Reduce Invasive Surveillance Methods in Lynch Syndrome [NA]
A clinical trial sponsored by UNICANCER will test whether non-invasive liquid biopsies can safely reduce invasive surveillance methods for p…
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CLINICAL_TRIALS guidance · 2026-01-07Clinical Trial Update: Multi-Organ Screening Recommendations in Patients With Lynch Syndrome
The document provides multi-organ screening recommendations for individuals with Lynch syndrome, outlining surveillance strategies to monito…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome [NA]
An ongoing clinical trial at the University of Alabama at Birmingham is testing a behavioral intervention to improve access to genetic servi…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule [NA]
A clinical trial is evaluating imaging the lower gastrointestinal tract using a Retro-TCE Capsule and is currently recruiting at Massachuset…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study) [NA]
A clinical trial is recruiting to evaluate a urine tumor DNA panel for screening urothelial cancer in individuals with Lynch syndrome (LS-UR…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome [NA]
A not-yet-recruiting clinical study at Centre Hospitalier Universitaire de Nîmes aims to determine how prevalent Muir-Torre Syndrome is amon…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome [Phase 2]
A Phase IIa randomized, double-blind trial comparing naproxen to aspirin for cancer immune interception in Lynch syndrome, with a focus on c…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results [NA]
A clinical trial update from Memorial Sloan Kettering Cancer Center describes a study to boost genetic testing in families with potential ca…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: The Cancer of the Pancreas Screening-5 CAPS5)Study [Phase 3]
A Phase 3 clinical trial led by Johns Hopkins University is currently recruiting participants to screen for pancreatic cancer in Peutz-Jeghe…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care [NA]
A completed clinical trial evaluating universal DNA sequencing of endometrial cancer to detect Lynch syndrome and guide personalized care fo…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire [NA]
A clinical trial conducted by the University of British Columbia is recruiting to assess uterine cancer risk in Lynch syndrome carriers usin…
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CLINICAL_TRIALS withdrawal · 2025-09-10Clinical Trial Update: Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study [Phase 1]
This document reports the withdrawal of a Phase 1 trial evaluating the combination of nivolumab and ipilimumab in pediatric and young adult …
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Clinical Validation of Sophia Genetics Assay
Clinical trial update reporting validation of the Sophia Genetics assay, with NOT_YET_RECRUITING status across ovarian cancer, breast cancer…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: CAD-EYE System for the Detection of Neoplastic Lesions in Patients With Lynch Syndrome [NA]
A clinical trial update indicates that the CAD-EYE System is being studied to detect neoplastic lesions in patients with Lynch syndrome and …
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
Mayo Clinic is recruiting a study that collects blood and stool samples from Lynch syndrome patients to detect colorectal cancer or advanced…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Smart Measurement of Circulating Tumor DNA [NA]
This entry describes a clinical trial from Erasmus Medical Center evaluating a smart measurement of circulating tumor DNA in colorectal canc…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Atorvastatin ± Aspirin in Lynch Syndrome Syndrome [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating atorvastatin with or without aspirin in Lynch syndrome has completed.
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes [NA]
A clinical trial update describing a patient-centered decision support study for hereditary cancer syndromes, sponsored by HealthPartners In…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome [Phase 3]
A Phase 3 clinical trial update evaluating whether low-dose aspirin can prevent new or recurrent colorectal adenomas in people with Lynch sy…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study [NA]
Completed feasibility study evaluating a workbook to improve cascade screening uptake for Lynch syndrome, with results posted.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome
This clinical trial update describes cascade genetic testing in families with newly diagnosed hereditary breast and ovarian cancer syndrome.…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Lynch Syndrome in Colorectal Cancer Surgery
A clinical trial (NCT06990633) investigating Lynch syndrome in colorectal cancer surgery is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Colonoscopy Check-up in People With Lynch Syndrome
A completed clinical trial from Imperial College London evaluating colonoscopy surveillance in people with Lynch syndrome.