Lynch Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Results: Colonoscopy Check-up in People With Lynch Syndrome
Clinical trial results for a colonoscopy screening program in people with Lynch syndrome are reported as completed with results posted.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Lynch Syndrome X-Talk of Enteral Mucosa With Immune System
A clinical trial registration indicates a recruiting study on the interaction between enteral mucosa and the immune system in people with Ly…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Videocapsule Endoscopy in Lynch Syndrome [NA]
The study is a recruiting trial evaluating videocapsule endoscopy in individuals with Lynch syndrome and related gene mutations, with focus …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families [NA]
This is a research protocol/status update for the Kindred web-based program to improve understanding of genetic cancer risk and testing in A…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: The Yield of Artificial Intelligence (GI Genius) in Lynch Syndrome - A Randomized Tandem-colonoscopy Trial [NA]
A randomized tandem-colonoscopy trial assesses the yield of the GI Genius AI system in Lynch syndrome; the study status is completed.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: FITting Non-invasive Tests in Lynch Syndrome Surveillance
Ongoing University of Chicago trial evaluating non-invasive tests for colorectal cancer surveillance in Lynch syndrome; recruitment is curre…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families [NA]
Clinical trial investigating weight management and health behavior interventions to lower cancer risk in BRCA-positive individuals and Lynch…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair [Phase 3]
Phase 3 trial evaluating chemotherapy with or without atezolizumab in stage III colon cancer with mismatch repair deficiency; results have b…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome [Phase 2]
A Phase 2 clinical trial is evaluating a combination of vaccines for cancer prevention in people with Lynch syndrome.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome Carriers [Phase 1]
A first-in-human Phase 1 trial evaluating a dendritic cell vaccine loaded with frameshift-derived neopeptides to prevent cancer in Lynch syn…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma [Phase 1]
Phase 1 trial of pembrolizumab in pediatric patients with recurrent or refractory high-grade gliomas, including diffuse intrinsic pontine gl…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Pediatric Reporting of Adult-Onset Genomic Results [EARLY_Phase 1]
Geisinger Clinic's EARLY Phase 1 trial update reports completion and posting of results regarding pediatric reporting of adult-onset genomic…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
This clinical trial update outlines the Pancreas Interception Center (PIC) focused on early detection, prevention, and novel therapeutics fo…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Scalable Communication Modalities for Returning Genetic Research Results [NA]
The study evaluated scalable communication modalities for returning genetic research results to participants. The trial focused on hereditar…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Small Bowel Capsule Endoscopy in Lynch Syndrome
A ClinicalTrials.gov entry indicates a study evaluating small bowel capsule endoscopy in individuals with Lynch syndrome is currently recrui…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention [NA]
The study IGNITE-TX is a feasibility trial from MD Anderson Cancer Center to identify individuals for genetic testing and treatment across m…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members [NA]
Clinical trial evaluating energy balance interventions to increase physical activity in BRCA mutation carriers, Lynch syndrome patients, CLL…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection
This clinical trial explores liquid biopsy and machine learning to detect early colorectal cancer, colorectal adenomas, Lynch syndrome-assoc…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients [Phase 1, Phase 2]
Clinical trial update on the cancer preventive vaccine Nous-209 for Lynch syndrome patients, with Phase 1 and Phase 2 trials currently activ…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome
Clinical trial update on evaluating capsule colonoscopy for Lynch syndrome patients. The study is currently NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome [NA]
A clinical trial is evaluating a menstrual cup as a noninvasive method for early detection of endometrial cancer in women with Lynch syndrom…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of Cancer [NA]
Clinical trial exploring the impact of ultra-processed food consumption on people at high risk of cancer; recruitment has not yet started.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Preventive Dendritic Cell Vaccination for Lynch Syndrome [Phase 1, Phase 2]
The document describes a Phase 1/2 clinical trial evaluating preventive dendritic cell vaccination for individuals with Lynch syndrome, whic…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes
A Memorial Sloan Kettering study is evaluating the gut microbiome using metagenomics in patients with Lynch syndrome and other hereditary co…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Overcoming Barriers to Uptake of Cascade Screening [NA]
This clinical trial update focuses on strategies to overcome barriers to cascade screening uptake for Lynch syndrome. The study status is no…