Lynch Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Results: Colonoscopy Check-up in People With Lynch Syndrome
Clinical trial results for a colonoscopy screening program in people with Lynch syndrome are reported as completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair [Phase 3]
Phase 3 trial evaluating chemotherapy with or without atezolizumab in stage III colon cancer with mismatch repair deficiency; results have b…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Pediatric Reporting of Adult-Onset Genomic Results [EARLY_Phase 1]
Geisinger Clinic's EARLY Phase 1 trial update reports completion and posting of results regarding pediatric reporting of adult-onset genomic…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Scalable Communication Modalities for Returning Genetic Research Results [NA]
The study evaluated scalable communication modalities for returning genetic research results to participants. The trial focused on hereditar…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Overcoming Barriers to Uptake of Cascade Screening [NA]
This clinical trial update focuses on strategies to overcome barriers to cascade screening uptake for Lynch syndrome. The study status is no…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care [NA]
A completed clinical trial evaluating universal DNA sequencing of endometrial cancer to detect Lynch syndrome and guide personalized care fo…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Atorvastatin ± Aspirin in Lynch Syndrome Syndrome [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating atorvastatin with or without aspirin in Lynch syndrome has completed.
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study [NA]
Completed feasibility study evaluating a workbook to improve cascade screening uptake for Lynch syndrome, with results posted.
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Colonoscopy Check-up in People With Lynch Syndrome
A completed clinical trial from Imperial College London evaluating colonoscopy surveillance in people with Lynch syndrome.
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer [EARLY_Phase 1]
Early-phase trial update shows termination of a tislelizumab study for recurrent mismatch repair-deficient endometrial cancer.
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy [Phase 2]
Phase 2 trial evaluating Nivolumab to prevent colon adenomas in participants with Lynch syndrome and a history of partial colectomy. The stu…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE) [Phase 2]
Phase 2 clinical trial update evaluating omega-3 fatty acids for colorectal cancer prevention in patients with Lynch syndrome.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome Patients [Phase 3]
Phase 3 clinical trial update for a PD-1 antibody aimed at preventing adenomatous polyps and second primary tumors in Lynch syndrome patient…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: High Definition White-Light Colonoscopy vs. Chromoendoscopy for Surveillance of Lynch Syndrome. [NA]
A completed clinical trial comparing high-definition white-light colonoscopy with chromoendoscopy for surveillance in patients with Lynch sy…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: I-Scan For Colon Polyp Detection In HNPCC [NA]
Completed clinical trial evaluating I-Scan imaging for colon polyp detection in patients with Lynch syndrome.
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CLINICAL_TRIALS trial_result · 2017-07-05Clinical Trial Update: Identifying Patients With Hereditary and Familial Colorectal Cancer by Using an Online Risk Tool [NA]
This clinical trial update reports completion of a study evaluating an online risk tool to identify patients with hereditary and familial co…
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: Integrating Genetic Testing for Lynch Syndrome in a Managed Care Setting [NA]
A completed clinical trial sponsored by Kaiser Permanente examined how integrating genetic testing for Lynch syndrome within a managed care …
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: Finding the Best Dose of Aspirin to Prevent Lynch Syndrome Cancers [Phase 3]
Phase 3 trial update evaluating the best aspirin dose to prevent Lynch syndrome–associated cancers; the study is currently not yet recruitin…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Chromoendoscopy to Decrease the Risk of Colorectal Neoplasia in Lynch Syndrome [NA]
This entry reports the completion of a clinical trial evaluating chromoendoscopy to reduce colorectal neoplasia risk in people with Lynch sy…
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Screening for Gynecologic Cancers in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients
Completed trial update on screening for gynecologic cancers in women with Lynch syndrome (hereditary nonpolyposis colorectal cancer).
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: Molecular Screening for Lynch Syndrome in Southern Denmark
This completed clinical trial evaluated molecular screening for Lynch syndrome in Southern Denmark, focusing on identifying Lynch syndrome a…
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CLINICAL_TRIALS trial_result · 2014-12-09Clinical Trial Update: Capsule Endoscopy to Screen for Small Bowel Neoplasia in Lynch Syndrome [EARLY_Phase 1]
This EARLY phase 1 trial update reports the completion of a study evaluating capsule endoscopy as a screening method for small bowel neoplas…
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CLINICAL_TRIALS trial_result · 2014-09-05Clinical Trial Update: Educational CD-ROM Compared With Standard Informed Consent for Patients With Colorectal Cancer or a Family History of Colorectal Cancer [NA]
An educational tool trial comparing a CD-ROM to standard informed consent was completed for patients with colorectal cancer and those with a…
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome [Phase 3]
Phase 3 trial evaluating intrauterine levonorgestrel with observation versus observation alone to prevent atypical endometrial hyperplasia a…
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CLINICAL_TRIALS trial_result · 2012-02-22Clinical Trial Update: Telemedicine vs. Face-to-Face Cancer Genetic Counseling [NA]
The study comparing telemedicine and face-to-face genetic counseling for people at risk of hereditary breast/ovarian cancer and Lynch syndro…