Lynch Syndrome
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study) [NA]
A clinical trial is recruiting to evaluate a urine tumor DNA panel for screening urothelial cancer in individuals with Lynch syndrome (LS-UR…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome [NA]
A not-yet-recruiting clinical study at Centre Hospitalier Universitaire de Nîmes aims to determine how prevalent Muir-Torre Syndrome is amon…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome [Phase 2]
A Phase IIa randomized, double-blind trial comparing naproxen to aspirin for cancer immune interception in Lynch syndrome, with a focus on c…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results [NA]
A clinical trial update from Memorial Sloan Kettering Cancer Center describes a study to boost genetic testing in families with potential ca…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: The Cancer of the Pancreas Screening-5 CAPS5)Study [Phase 3]
A Phase 3 clinical trial led by Johns Hopkins University is currently recruiting participants to screen for pancreatic cancer in Peutz-Jeghe…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire [NA]
A clinical trial conducted by the University of British Columbia is recruiting to assess uterine cancer risk in Lynch syndrome carriers usin…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Clinical Validation of Sophia Genetics Assay
Clinical trial update reporting validation of the Sophia Genetics assay, with NOT_YET_RECRUITING status across ovarian cancer, breast cancer…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: CAD-EYE System for the Detection of Neoplastic Lesions in Patients With Lynch Syndrome [NA]
A clinical trial update indicates that the CAD-EYE System is being studied to detect neoplastic lesions in patients with Lynch syndrome and …
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
Mayo Clinic is recruiting a study that collects blood and stool samples from Lynch syndrome patients to detect colorectal cancer or advanced…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Smart Measurement of Circulating Tumor DNA [NA]
This entry describes a clinical trial from Erasmus Medical Center evaluating a smart measurement of circulating tumor DNA in colorectal canc…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes [NA]
A clinical trial update describing a patient-centered decision support study for hereditary cancer syndromes, sponsored by HealthPartners In…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome [Phase 3]
A Phase 3 clinical trial update evaluating whether low-dose aspirin can prevent new or recurrent colorectal adenomas in people with Lynch sy…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome
This clinical trial update describes cascade genetic testing in families with newly diagnosed hereditary breast and ovarian cancer syndrome.…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Lynch Syndrome in Colorectal Cancer Surgery
A clinical trial (NCT06990633) investigating Lynch syndrome in colorectal cancer surgery is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Dendritic Cell Vaccination in Patients With Lynch Syndrome or Colorectal Cancer With MSI [Phase 1, Phase 2]
This update describes an ongoing phase 1/2 clinical trial of a dendritic cell vaccine in patients with Lynch syndrome or colorectal cancer w…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome
This completed clinical trial investigated how frequently precursors to endometrial cancer occur in individuals with Lynch syndrome.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Predictive Value of PREMM5, MMRpredict, and Universal Tumor Screening for Lynch Syndrome in Vietnam
This clinical trial evaluates the predictive value of PREMM5, MMRpredict, and universal tumor screening for Lynch syndrome in Vietnam, with …
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland
This update describes a Swiss clinical trial at the University of Basel evaluating cascade genetic testing for hereditary breast and ovarian…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Lynch Syndrome Integrative Epidemiology and Genetics
A clinical trial sponsored by the University of Colorado, Denver is studying patients with Lynch syndrome and is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: DYNAMICS-LYNCH：DNA Methylation Analysis in Stool for Screening of Lynch Syndrome-Associated Colorectal Cancer
This clinical trial investigates stool DNA methylation analysis as a screening tool for Lynch syndrome-associated colorectal cancer; the stu…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome [Phase 2]
Phase 2 clinical trial update on using mesalamine to prevent colorectal cancer in Lynch syndrome; the study is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Video Capsule Examination in Patients With Lynch Syndrome [NA]
Status update for NCT06712095 shows recruitment underway for a study assessing video capsule examination in patients with Lynch syndrome and…
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: Prostate Cancer Genetic Risk Evaluation and Screening Study
Massachusetts General Hospital's clinical trial update describes a recruiting study to evaluate genetic risk and screening for prostate canc…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Registry for Women Who Are At Risk Or May Have Lynch Syndrome
A completed registry study examining women who are at risk for or may have Lynch syndrome (hereditary nonpolyposis colorectal cancer).
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: EC_ItaLynch: Mainstreaming the Diagnosis of Lynch Syndrome
This clinical trial evaluates a streamlined approach to diagnosing Lynch syndrome in the context of Lynch syndrome and endometrial cancer. T…