Lung Transplant Rejection
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after single-…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Assessment of Chronic Lung Allograft Dysfunction Using Single-breath & Multi-breath Hyperpolarized Xenon-129 MRI
A clinical trial update noting the termination of a study evaluating single-breath and multi-breath Hyperpolarized Xenon-129 MRI to assess c…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: HP 129Xe MRI for Evaluation of CLAD in Lung Transplant Recipients [Phase 2]
Phase 2 study evaluating HP 129Xe MRI for assessment of chronic lung allograft dysfunction in lung transplant recipients has been terminated…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2) [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after double-lung tr…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Clinical Trials in Organ Transplantation Extension Study
This document provides an update on the completed extension study within the Clinical Trials in Organ Transplantation program, focusing on l…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: An Open Label Trial Evaluating the Safety, Tolerability, Efficacy and Pharmacokinetic Profile of Tacrolimus Inhalation Powder in Adult Lung Transplant Recipients [Phase 2]
An open-label Phase 2 trial evaluating the safety, tolerability, efficacy, and pharmacokinetic profile of tacrolimus inhalation powder in ad…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Extracorporeal Photopheresis (ECP) After Lung Transplantation [NA]
Clinical trial update for extracorporeal photopheresis after lung transplantation indicates the study has completed, sponsored by the Medica…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: A Prospective Randomized Trial of ECP in Subclinical AMR [NA]
Status update on a prospective randomized trial evaluating extracorporeal photopheresis for subclinical antibody-mediated rejection in lung …
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Comparison of Transbronchial Cryobiopsy and Forceps Biopsy in Lung Transplant Recipients [NA]
A completed clinical trial comparing transbronchial cryobiopsy and forceps biopsy in lung transplant recipients. The study aims to evaluate …
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: CLAD: Finding Biomarkers to Predict Rejection and/ or Outcome After Lung Transplantation
The CLAD study investigating biomarkers to predict rejection and outcomes after lung transplantation has been terminated.
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: Assessment of Donor Derived Cell Free DNA and Utility in Lung Transplantation [NA]
Clinical trial on donor-derived cell-free DNA in lung transplantation has terminated; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-01-09Clinical Trial Update: Pirfenidone for Restrictive Chronic Lung Allograft Dysfunction [Phase 2]
Phase 2 trial update on pirfenidone for restrictive chronic lung allograft dysfunction in lung transplant patients; study completed with res…
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: Combination Therapy With Carfilzomib for the Antibody-Mediated Rejection Diagnosis in Lung Transplantation [Phase 2]
Phase 2 clinical trial evaluating combination therapy with carfilzomib for antibody-mediated rejection in lung transplantation completed wit…
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation [Phase 2]
Phase 2 pilot study of belatacept for immunosuppression in lung transplant recipients has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: Adipose Derived Mesenchymal Cell Treatment in Lungtransplantation [Phase 1, Phase 2]
Phase 1/2 trial evaluating adipose-derived mesenchymal cell treatment for lung transplant rejection.
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Prospective Study for Transplant Optimization Using Functional Imaging (TROFI) [Phase 2]
Phase 2 prospective trial TROFI evaluating transplant optimization using functional imaging; the study sponsored by FLUIDDA nv has been term…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Transplant Optimization Using Functional Imaging (TROFI) [NA]
The TROFI trial evaluating transplant optimization using functional imaging has completed, focusing on patients with bronchiolitis obliteran…
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CLINICAL_TRIALS trial_result · 2012-01-26Clinical Trial Update: Alveoscopy, Endoscopic Confocal Microscopy and Lung Rejection, Parenchymal Lung Diseases in Vivo
Completed Mayo Clinic clinical trial evaluating alveoscopy and endoscopic confocal microscopy to monitor lung rejection and parenchymal lung…