Lung Transplant Rejection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung Transplantation
A ClinicalTrials.gov entry for GRAfT 2.0, a multimodal prospective study to define mechanisms and clinical features of acute and chronic rej…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction [Phase 3]
A Phase 3 clinical trial evaluating the effectiveness of belumosudil tablets in adults with chronic lung allograft dysfunction after lung tr…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Developing Hyperpolarized Gas MRI Signatures to Detect and Manage Acute Cellular Rejection [Phase 2]
Phase 2 clinical trial update investigating hyperpolarized gas MRI signatures to detect and manage acute cellular rejection in lung transpla…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: TRAnscriptional Profile of Peripheral Blood Cells in Patient With Chronic Kidney and Lung Rejection: Correlation With Response to Extracorporeal Photo-aphereSiS
This clinical trial update reports transcriptional profiling of peripheral blood cells in a patient with kidney and lung graft rejection and…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation
A clinical trial evaluating microarray-based diagnostics and potential therapies in lung transplantation, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after single-…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Assessment of Chronic Lung Allograft Dysfunction Using Single-breath & Multi-breath Hyperpolarized Xenon-129 MRI
A clinical trial update noting the termination of a study evaluating single-breath and multi-breath Hyperpolarized Xenon-129 MRI to assess c…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Liquid biopsiEs fOr luNg AllogRaft Damage classificatiOn - LEONARDO
The LEONARDO study investigates using liquid biopsies to classify lung allograft damage, including rejection and infection, and is currently…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: HP 129Xe MRI for Evaluation of CLAD in Lung Transplant Recipients [Phase 2]
Phase 2 study evaluating HP 129Xe MRI for assessment of chronic lung allograft dysfunction in lung transplant recipients has been terminated…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2) [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of liposome-encapsulated cyclosporine A for bronchiolitis obliterans after double-lung tr…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Analysis of Volatile Organic Compounds in the Breath of Lung Transplant Rejection Patients Using Infrared Spectroscopy
Clinical trial update on a terminated study evaluating volatile organic compounds in breath, using infrared spectroscopy, to detect lung tra…
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CLINICAL_TRIALS other · 2025-05-29Clinical Trial Update: Long Term Follow up of the LTOG Cohort
ClinicalTrials.gov update describes a long-term follow-up study of the Lung Transplant Outcomes Group (LTOG) cohort, currently enrolling by …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: LAMBDA 002 (Lung Registry) Study
The LAMBDA 002 (Lung Registry) study sponsored by Natera, Inc. is currently ACTIVE_NOT_RECRUITING, focusing on lung transplant rejection.
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: PREdiction of Chronic LUng Allograft Dysfunction
Clinical trial investigating prediction of chronic lung allograft dysfunction in lung transplant recipients; currently active but not recrui…
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CLINICAL_TRIALS research · 2025-04-21Clinical Trial Update: Cryoprobe Biopsy and Chronic Rejection in Lung Transplant Recipients [NA]
A Mayo Clinic-sponsored clinical trial evaluating cryoprobe biopsy in lung transplant recipients for chronic rejection is currently recruiti…
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CLINICAL_TRIALS withdrawal · 2025-04-11Clinical Trial Update: Isatuximab in Lung Transplant Recipients [EARLY_Phase 1]
A Phase 1 trial of isatuximab for antibody-mediated rejection in lung transplant recipients was withdrawn.
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Clinical Trials in Organ Transplantation Extension Study
This document provides an update on the completed extension study within the Clinical Trials in Organ Transplantation program, focusing on l…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: An Open Label Trial Evaluating the Safety, Tolerability, Efficacy and Pharmacokinetic Profile of Tacrolimus Inhalation Powder in Adult Lung Transplant Recipients [Phase 2]
An open-label Phase 2 trial evaluating the safety, tolerability, efficacy, and pharmacokinetic profile of tacrolimus inhalation powder in ad…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Extracorporeal Photopheresis (ECP) After Lung Transplantation [NA]
Clinical trial update for extracorporeal photopheresis after lung transplantation indicates the study has completed, sponsored by the Medica…
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CLINICAL_TRIALS research · 2024-07-26Clinical Trial Update: Safety of Endobronchial Mesenchymal Stromal Cells in the Treatment of Chronic Lung Allograft Dysfunction [Phase 1]
A Phase 1 trial is evaluating the safety of endobronchial mesenchymal stromal cells for chronic lung allograft dysfunction and is currently …
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: A Prospective Randomized Trial of ECP in Subclinical AMR [NA]
Status update on a prospective randomized trial evaluating extracorporeal photopheresis for subclinical antibody-mediated rejection in lung …
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Comparison of Transbronchial Cryobiopsy and Forceps Biopsy in Lung Transplant Recipients [NA]
A completed clinical trial comparing transbronchial cryobiopsy and forceps biopsy in lung transplant recipients. The study aims to evaluate …
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: CLAD: Finding Biomarkers to Predict Rejection and/ or Outcome After Lung Transplantation
The CLAD study investigating biomarkers to predict rejection and outcomes after lung transplantation has been terminated.
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CLINICAL_TRIALS trial_result · 2024-03-25Clinical Trial Update: Assessment of Donor Derived Cell Free DNA and Utility in Lung Transplantation [NA]
Clinical trial on donor-derived cell-free DNA in lung transplantation has terminated; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2023-01-09Clinical Trial Update: Pirfenidone for Restrictive Chronic Lung Allograft Dysfunction [Phase 2]
Phase 2 trial update on pirfenidone for restrictive chronic lung allograft dysfunction in lung transplant patients; study completed with res…