Liver Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Efficacy of Conventional Dose Protocol vs Low Dose Protocol Albumin Use in Patients With Cirrhosis and High Risk Spontaneous Bacterial Peritonitis [NA]
A clinical trial evaluating conventional-dose versus low-dose albumin administration in patients with liver cirrhosis at high risk for spont…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Rotational Thromboelastometry [ROTEM] vs Thromboelastography [TEG] Guided Blood Component Use in Patients With Cirrhosis of Liver With Non-variceal Bleeding. [NA]
This clinical trial compares ROTEM-guided versus TEG-guided use of blood components in patients with liver cirrhosis and non-variceal bleedi…
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CLINICAL_TRIALS research · 2024-07-30Clinical Trial Update: FMT for Alcohol Use Disorder in Cirrhotics. [NA]
A clinical trial in India is recruiting participants with liver cirrhosis and alcohol use disorder to evaluate fecal microbiota transplant (…
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: Evaluation of the Inter-center Variability of the Measurement of Thrombin Generation by the ST Genesia System
Completed clinical trial evaluating inter-center variability in thrombin generation measurements using the ST Genesia system.
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Safety and Adequacy of Trans-jugular Liver Biopsy in Patients With Liver Disease: SAFE-TJLB Study
A clinical trial update describing a study sponsored by the Institute of Liver and Biliary Sciences, India, evaluating the safety and adequa…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis [Phase 2, Phase 3]
Alverine is being evaluated in Phase 2 and Phase 3 trials for portal hypertension in patients with liver cirrhosis, and the study is not yet…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: To Study the Efficacy of Intravenous Neostigmine in Resolution of Acute GI Paralysis in Critically Ill Cirrhotics
This clinical trial evaluates whether intravenous neostigmine can effectively resolve acute gastrointestinal paralysis in critically ill pat…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
A clinical trial update announcing collection of blood from healthy individuals, patients with benign disease, and cancer patients sponsored…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia [Phase 2]
Phase 2 trial evaluating autologous bone marrow mononuclear cells for children with biliary atresia–related liver cirrhosis has completed.
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: Clinical Trial Multi-analyte Blood Test
Update on a Helio Genomics-sponsored clinical trial evaluating a multi-analyte blood test for liver cirrhosis. The current status of the tri…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Home-based Bimodal Lifestyle Intervention in Patients With Liver Cirrhosis Awaiting Orthotopic Liver Transplantation [NA]
This clinical trial update outlines a home-based bimodal lifestyle intervention for patients with liver cirrhosis awaiting orthotopic liver …
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Vibration Training Approach in Liver Cirrhosis [NA]
This registration describes a vibration training approach being studied for liver cirrhosis, with the study currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: PK Profile and Preliminary Efficacy of TNP-2092 Capsules in Liver Cirrhosis Patients With Hyperammonemia [Phase 1, Phase 2]
The update reports the pharmacokinetic profile and preliminary efficacy signals of the investigational drug TNP-2092 in patients with liver …
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Freiburg TIPS Registry
Clinical trial update for Freiburg's TIPS Registry showing ongoing recruitment for a registry study of portal hypertension-related condition…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: 4beta-hydroxycholesterol in Cirrhosis
A University of Oulu trial evaluating 4beta-hydroxycholesterol in liver cirrhosis has been suspended.
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Noninvasive Diagnosis Model for High-risk Varices in Cirrhosis
An update on a clinical trial evaluating a noninvasive diagnostic model to identify high-risk esophageal varices in patients with liver cirr…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Proton Pump Inhibitors in Cirrhotic Patients
A completed clinical trial evaluating proton pump inhibitors in patients with liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Statin Impact on Hepatic Decompensation [Phase 2, Phase 3]
Phase 2/3 trial investigating the impact of statins on hepatic decompensation and quality of life has been completed.
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: A Study to Assess the Efficacy, Safety, and Tolerability of Oral LPCN 1148 in Male Subjects With Cirrhosis of the Liver and Sarcopenia [Phase 2]
Phase 2 trial assessing oral LPCN 1148 for efficacy, safety, and tolerability in male subjects with liver cirrhosis and sarcopenia has compl…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Rifamycin in Minimal Hepatic Encephalopathy [Phase 2]
Phase 2 trial update for rifamycin in minimal hepatic encephalopathy has completed.
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Opioid Sparing Anesthesia in Patients With Liver Cirrhosis Undergoing Liver Resection [Phase 3]
Phase 3 clinical trial investigating opioid-sparing anesthesia in patients with liver cirrhosis undergoing liver resection has completed.
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CLINICAL_TRIALS trial_result · 2023-07-06Clinical Trial Update: Prolonged Release Pirfenidone for Advanced Residual Liver Fibrosis (MINERVA). [Phase 2]
Phase 2 trial update for prolonged-release pirfenidone in advanced residual liver fibrosis due to liver cirrhosis and chronic hepatitis C.
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FDA approval · 2023-06-28FDA Approved: SPIRONOLACTONE — Supplemental Application (Amneal Pharmaceuticals LLC)
The FDA approved a supplemental application for Spironolactone from Amneal Pharmaceuticals LLC.
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FDA approval · 2023-06-23FDA Approved: SPIRONOLACTONE — Supplemental Application (Oxford Pharmaceuticals, LLC)
FDA approved a supplemental application for spironolactone by Oxford Pharmaceuticals, LLC. The approval allows continued marketing of the ge…
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CLINICAL_TRIALS trial_result · 2023-06-07Clinical Trial Update: Study to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis [Phase 2]
A Phase 2 clinical trial evaluating CC-90001 for non-alcoholic fatty liver disease and liver cirrhosis was terminated; results were posted i…