Liver Cirrhosis
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-08-05EMA Authorised: Iqirvo (Elafibranor) — Ipsen Pharma
Elafibranor (Iqirvo) by Ipsen Pharma has been authorised with conditional approval as an orphan medicine for liver cirrhosis and biliary dis…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Use of Gender, Age, Alfa-fetoprotein (AFP), and Des-gamma-carboxyprothrombin (PIVKA-II) or GAAD Score in Addition to Ultrasound for Surveillance of People At-risk for Developing Hepatocellular Carcinoma in Asia in Order to Detect Early Liver Cancer [NA]
This clinical trial update describes a study evaluating GAAD score plus AFP/PIVKA-II or ultrasound for surveillance of people at risk for he…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Annual MRI Versus Biannual US for Surveillance of Hepatocellular Carcinoma in Liver Cirrhosis
A completed clinical trial comparing annual magnetic resonance imaging to biannual ultrasound for hepatocellular carcinoma surveillance in p…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients [NA]
A randomized controlled trial evaluating bariatric surgery as a treatment for severe nonalcoholic steatohepatitis with advanced liver fibros…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Effect of Babao Dan Capsule Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis [NA]
This clinical trial evaluates whether Babao Dan Capsule in combination with antiviral therapy can reduce the incidence of hepatocellular car…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Placement
An ongoing clinical trial assessing systemic and portal hemostasis in patients undergoing transjugular intrahepatic portosystemic shunt plac…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Deciphering the Mechanisms Involved in Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis
This clinical trial update reports on the mechanisms of microbial translocation across the spectrum of HCV-associated liver fibrosis, includ…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Safety and Efficacy of Ketogenic Diet for Promoting Weight Loss in Obese Individuals With Compensated NASH Cirrhosis [NA]
This clinical trial is evaluating the safety and efficacy of a ketogenic diet to promote weight loss in obese adults with compensated nonalc…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH) [Phase 2]
Phase 2 clinical trial to assess tolerability of BI 3802876 in adults with compensated liver cirrhosis due to metabolic dysfunction-associat…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Acute Kidney Injury in Patients With Liver Cirrhosis
A completed clinical trial sponsored by Sohag University investigating acute kidney injury in patients with liver cirrhosis.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Novel Extracorporeal Liver Support Therapy In ALCF and to Evaluate the Efficacy of DIALIVE 2.0, a Liver Dialysis Device. [Phase 3]
A Phase 3 clinical trial (NCT07347275) of DIALIVE 2.0, an extracorporeal liver dialysis device, for acute-on-chronic liver failure and liver…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Can Aspirin Reduce the Risk of HCC in Cirrhosis: The AspiRe HCC Trial [Phase 3]
Phase 3 trial assessing whether aspirin can reduce the risk of hepatocellular carcinoma in patients with liver cirrhosis; the AspiRe HCC Tri…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE) [Phase 2]
Phase 2 clinical trial MASTERPIECE evaluating microbiota transplant therapy for hepatic encephalopathy in cirrhosis; currently not yet recru…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome [Phase 2]
Phase 2 trial evaluating ambrisentan, an endothelin receptor antagonist, for hepatorenal syndrome; the study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: TEAS for Variceal Bleeding Endoscopy in Cirrhosis [NA]
A completed clinical trial evaluating TEAS for variceal bleeding management during endoscopy in patients with cirrhosis.
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EMA approval · 2026-04-09EMA Authorised: Kayshild (semaglutide) — Novo Nordisk A/S
EU medicines regulator authorised Kayshild (semaglutide) by Novo Nordisk A/S for non-alcoholic fatty liver disease and liver cirrhosis, with…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Online Prehabilitation for Patients Awaiting Liver Transplantation [NA]
An online prehabilitation program for patients awaiting liver transplantation is currently recruiting, sponsored by the University of Albert…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Efficacy of PegInterferon-Ribavirin-Boceprevir Therapy in Patients Infected With G1 HCV With Cirrhosis, Awaiting Liver Transplantation [Phase 2]
A Phase 2 trial evaluating pegylated interferon, ribavirin, and boceprevir for genotype 1 hepatitis C with cirrhosis awaiting liver transpla…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Pantoprazole After Prophylactic Endoscopic Variceal Treatment [NA]
A clinical trial is evaluating pantoprazole after prophylactic endoscopic treatment of esophageal and gastric varices in patients with liver…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection [NA]
A clinical trial update describes a vagus nerve-guided laparoscopic splenectomy with azygoportal disconnection for cirrhosis-related hypersp…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: SAMe for Prevention of Liver Cancer in MASLD-Related Cirrhosis [Phase 2]
A Phase 2 clinical trial evaluating S-adenosyl-L-methionine (SAMe) for prevention of liver cancer in MASLD-related cirrhosis; recruitment no…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Hepatocellular Carcinoma on Cirrhosis With Child A/B7 and Hepatic Intra Arterial Injection of Idarubicin/Lipiodol Emulsion [Phase 2]
Phase 2 trial evaluating hepatic arterial idarubicin with lipiodol emulsion for hepatocellular carcinoma in cirrhosis; the study (NCT0372763…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: A Clinical Trial Evaluating the Safety of Hydronidone Capsules in Patients With Hepatic Fibrosis and Liver Cirrhosis [Phase 3]
A Phase 3 clinical trial evaluating the safety of Hydronidone capsules in patients with hepatic fibrosis and liver cirrhosis due to chronic …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Heart Problems in Children With Chronic Liver Disease
Clinical trial update describing a study on heart problems in children with chronic liver disease, currently not yet recruiting, involving c…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Implications of Fecal Microbiota Transplantation in Modulating the Effects of Liver Cirrhosis [Phase 3]
A Phase 3 clinical trial assessing fecal microbiota transplantation for modulating the effects of liver cirrhosis has completed, with result…