Leptomeningeal Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases [Phase 1]
Phase 1 clinical trial update for HER2-directed CAR-T cells in patients with recurrent brain or leptomeningeal metastases from breast cancer…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis [Phase 1]
A Phase 1 clinical trial investigating Deferoxamine (DFO) for treating leptomeningeal metastases is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases [Phase 2]
A Phase 2 clinical trial is assessing furmonertinib in combination with intrathecal chemotherapy and stereotactic radiotherapy for EGFR-muta…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessing Sacituzumab Govitecan in combination with intrathecal chemotherapy for leptomeningeal metastases from H…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: High-Dose Firmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed in the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer With Leptomeningeal Metastasis [Phase 2]
Phase 2 clinical trial evaluating high-dose Firmonertinib with Bevacizumab and intrathecal Pemetrexed for EGFR-mutated non-small cell lung c…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Cerebrospinal Fluid Cytology-guided Intrathecal Chemo-holiday Therapy for EGFR-positive NSCLC Leptomeningeal Metastases [Phase 2]
A Phase 2 clinical trial at Zhejiang Cancer Hospital evaluates cerebrospinal fluid cytology-guided intrathecal chemotherapy with chemo-holid…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study [Phase 2]
Phase II single-arm study evaluating furmonertinib plus bevacizumab as first-line therapy for EGFR-mutant non-small cell lung cancer with br…