Lennox-gastaut Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome [Phase 3]
Phase 3 trial evaluating soticlestat as add-on therapy in children and adults with Dravet syndrome or Lennox-Gastaut syndrome has terminated…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: A Study of Soticlestat in Adults and Children With Rare Epilepsies [Phase 2]
Takeda reports termination of a Phase 2 study of Soticlestat in adults and children with rare epilepsies, with results posted.
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: RNS System LGS Feasibility Study [Phase 2]
The RNS System LGS feasibility study (Phase 2) is currently active but not recruiting, evaluating responsive neurostimulation for Lennox-Gas…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy [Phase 2]
This report covers a long-term, open-label Phase 2 safety study of LP352 in developmental and epileptic encephalopathy, including Dravet and…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome [Phase 3]
Phase 3 study update reporting long-term safety data for ZX008 (fenfluramine hydrochloride) oral solution in children and adults with epilep…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures [Phase 3]
A Phase 3 study of adjunctive cannabidiol oral solution GWP42003-P in children with tuberous sclerosis complex, Dravet syndrome, or Lennox-G…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome [Phase 3]
A Phase 3 study of Soticlestat as add-on therapy for children and adults with Dravet syndrome or Lennox-Gastaut syndrome has been terminated…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot [NA]
The CADET pilot trial evaluating adaptive deep brain stimulation for pediatric epilepsy has completed, with no outcome data provided in the …
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: An Extended Access Program (EAP) for Participants Who Have Completed Rufinamide Study E2080-G000-303
This update announces an Extended Access Program for participants who completed the Rufinamide study E2080-G000-303, providing continued acc…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome [Phase 3]
Phase 3 study evaluating ZX008 (fenfluramine hydrochloride) as adjunctive therapy for Lennox-Gastaut syndrome has completed and its results …
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine [Phase 3]
Phase 3 trial evaluating soticlestat in Dravet syndrome or Lennox-Gastaut syndrome patients with prior fenfluramine exposure was terminated;…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies [Phase 1, Phase 2]
Clinical trial update indicates LP352 has completed Phase 1/2 studies in developmental and epileptic encephalopathies. The program covers Dr…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome [Phase 3]
A Phase 3 study evaluating soticlestat as add-on therapy for Lennox-Gastaut syndrome across children, teenagers, and adults has completed, a…
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: Add-on Therapy With Low Dose Fenfluramine in Lennox Gastaut Epilepsy [Phase 2]
Phase 2 trial investigating add-on low-dose fenfluramine in Lennox-Gastaut epilepsy.
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: Investigation of Cognitive Outcomes With Cannabidiol Oral Solution [Phase 4]
Phase 4 investigation of cannabidiol oral solution for cognitive outcomes in Lennox-Gastaut Syndrome was withdrawn.
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CLINICAL_TRIALS trial_result · 2022-03-09Clinical Trial Update: Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastaut Syndrome [Phase 3]
Phase 3 study of perampanel as an adjunctive treatment for inadequately controlled seizures in Lennox-Gastaut syndrome was terminated with r…
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CLINICAL_TRIALS trial_result · 2022-02-03Clinical Trial Update: An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Adults With Dravet or Lennox-Gastaut Syndromes [Phase 3]
Open-label extension study of cannabidiol (GWP42003-P) in children and adults with Dravet or Lennox-Gastaut syndromes completed; results pos…
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CLINICAL_TRIALS trial_result · 2022-01-03Clinical Trial Update: The Effects of Cannabidiol (CBD) on Electrical and Autonomic Cardiac Function in Children With Severe Epilepsy [Phase 1, Phase 2]
A terminated phase 1/2 clinical trial evaluating the effects of cannabidiol (CBD) on electrical and autonomic cardiac function in children w…
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies [Phase 2]
Phase 2 trial in pediatric epilepsy evaluating TAK-935 as adjunctive therapy; completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: Research on Cognitive Effect of Cannabidiol on Dravet Syndrome and Lennox-Gastaut SyndromeGastaut Syndrome [Phase 3]
Phase 3 trial update investigating the cognitive effects of cannabidiol in Dravet Syndrome and Lennox-Gastaut Syndrome.
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CLINICAL_TRIALS trial_result · 2019-08-06Clinical Trial Update: Study of Rufinamide in Pediatric Subjects 1 to Less Than 4 Years of Age With Lennox-Gastaut Syndrome Inadequately Controlled With Other Anti-epileptic Drugs [Phase 3]
Phase 3 clinical trial of Rufinamide in children aged 1 to <4 years with Lennox-Gastaut Syndrome; study completed with results posted in 201…
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: A Long Term Extension Study of E2080 in Lennox-Gastaut Patients [Phase 3]
Phase 3 long-term extension study of E2080 in Lennox-Gastaut syndrome completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults [Phase 3]
Phase 3 clinical trial evaluating CBD as adjunctive treatment for seizures in Lennox-Gastaut syndrome; trial completed with results posted i…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Efficacy and Safety of GWP42003-P for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults [Phase 3]
Phase 3 trial update on GWP42003-P for seizures in Lennox-Gastaut syndrome, reporting efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2016-06-29Clinical Trial Update: Transcranial Direct Current Stimulation, Treatment of Childhood Drug-Resistant Lennox-Gastaut Syndrome, A Pilot Study [Phase 4]
Phase 4 pilot study evaluating transcranial direct current stimulation for treatment-resistant Lennox-Gastaut syndrome in children has compl…