Intrahepatic Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic Cholangiocarcinoma [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating cryoablation in combination with lenvatinib and QL1706 for advanced …
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma
This clinical trial update notes that the study evaluating preoperative lymph node evaluation in cholangiocarcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer
This clinical trial update reports the termination of a feasibility study evaluating multi-platform profiling of resected biliary tract canc…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Study to Evaluate MIV-818 in Patients With Liver Cancer Manifestations [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating MIV-818 in liver cancer manifestations (hepatocellular carcinoma and intrahepatic cholangioc…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer [Phase 2]
Phase 2 trial evaluating atezolizumab plus varlilumab with or without cobimetinib in advanced biliary tract cancers, with results posted in …
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma [Phase 2, Phase 3]
A randomized Phase 2/3 trial comparing selective internal radiation therapy (SIRT) followed by cisplatin-gemcitabine versus cisplatin-gemcit…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations [Phase 1]
Phase 1 study of KIN-3248 in FGFR2/3-altered advanced tumors was terminated. The trial enrolled patients with intrahepatic cholangiocarcinom…
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial evaluating durvalumab and tremelimumab with or without capecitabine as adjuvant therapy for biliary tract cancers; th…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: PD-L1 Antibody Combined With CTLA-4 Antibody for Patients With Advanced Intrahepatic Cholangiocarcinoma Who Progressed After Standard Treatment [Phase 2]
A Phase 2 clinical trial is evaluating the combination of a PD-L1 antibody with a CTLA-4 antibody in patients with advanced intrahepatic cho…
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements [Phase 2]
This Phase 2 trial of pemigatinib for advanced intrahepatic cholangiocarcinoma with FGFR2 fusions has been terminated. The study status indi…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Hepatic Arterial Infusion (HAI) With Floxuridine (FUDR) and Dexamethasone (Dex) Combined With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma (ICC) [Phase 2]
Phase 2 clinical trial evaluating hepatic arterial infusion with floxuridine and dexamethasone in combination with systemic gemcitabine and …
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)
Expanded Access for ABC294640 (Yeliva) in advanced cholangiocarcinoma has been closed and is no longer available.
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant Treatments
This clinical trial update describes liver transplantation for patients with unresectable intrahepatic cholangiocarcinoma who have achieved …
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2 trial evaluating cryoablation in combination with sintilimab and lenvatinib for advanced intrahepatic cholangiocarcinoma has compl…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: A Clinical Study of DEB-TACE Combined With Surufatinib and Camrelizumab in the Treatment of Inoperable or Metastatic ICC [Phase 2]
Phase 2 study of DEB-TACE combined with Surufatinib and Camrelizumab for inoperable or metastatic intrahepatic cholangiocarcinoma has comple…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Two-cohort Study of Toripalimab(PD1)+Lenvatnib, or Gemox+Lenvatinib in Advanced Intrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2 trial evaluating two regimens—toripalimab with lenvatinib, or gemcitabine/oxaliplatin with lenvatinib—in advanced intrahepatic cho…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Liver Transplantation for Early Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 trial evaluating liver transplantation for early intrahepatic cholangiocarcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Toripalimab Combined With Gemcitabine and Cisplatin (GemCis) as Preoperative Neoadjuvant Therapy for Resectable Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 trial evaluating toripalimab in combination with gemcitabine and cisplatin as preoperative neoadjuvant therapy for resectable intrah…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: A Machine-learning Model to Predict Lymph Node Metastasis of Intrahepatic Cholangiocarcinoma
A completed clinical trial update evaluating a machine-learning model to predict lymph node metastasis in intrahepatic cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Gemcitabine-Cisplatin-90Y TARE for Unresectable Intrahepatic Cholangiocarcinoma [NA]
A clinical trial evaluating gemcitabine, cisplatin, and Yttrium-90 radioembolization for unresectable intrahepatic cholangiocarcinoma has be…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Durvalumab and Tremelimumab With Platinum-based Chemotherapy in Intrahepatic Cholangiocarcinoma (ICC) [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of Durvalumab plus Tremelimumab with platinum-based chemotherapy for intra…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers [Phase 3]
A Phase 3 trial evaluating gemcitabine hydrochloride and cisplatin with or without nab-paclitaxel in newly diagnosed advanced biliary tract …
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Adebrelimab Combined with Irinotecan Liposomes, 5-FU, CF ± Lenvatinib As First-line Treatment for Advanced ICC [Phase 2]
Phase 2 trial evaluating adebrelimab plus irinotecan liposome, 5-FU, and CF with or without lenvatinib as first-line treatment for advanced …
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Low-dose Gemcitabine and Cisplatin and PD-1/PD-L1 Antibody Therapy in Intrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2 trial evaluates low-dose gemcitabine and cisplatin with a PD-1/PD-L1 antibody in intrahepatic cholangiocarcinoma; the study is cur…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma [Phase 2]
Open-label Phase IIa/IIb trial evaluating VG161 as monotherapy and in combination with nivolumab for hepatocellular carcinoma or intrahepati…