Hypophosphatasia
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa [Phase 3]
Phase 3 trial of ALXN1850 versus placebo in adolescents and adults with hypophosphatasia who have not previously been treated with asfotase …
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Pilot Trial of Single Dose Ilofotase Alfa in Hypophosphatasia [Phase 1, Phase 2]
A Phase 1/2 pilot trial evaluating a single-dose Ilofotase alfa for hypophosphatasia has completed, and the results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Study of ALXN1850 in Participants With Hypophosphatasia (HPP) [Phase 1]
Phase 1 trial of ALXN1850 in hypophosphatasia has completed, and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Serum Alkaline Phosphatase Levels In Healthy Turkish Children [NA]
A completed clinical trial in Turkey assessed serum alkaline phosphatase levels in healthy children in the context of alkaline phosphatase d…
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)
A completed clinical trial update examining patient-reported outcomes in adults with pediatric-onset hypophosphatasia treated with Strensiq …
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CLINICAL_TRIALS trial_result · 2022-09-16Clinical Trial Update: Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP) [Phase 2]
Phase 2 dose-escalation trial evaluating safety and tolerability of multiple infusions of BPS804 in adults with hypophosphatasia completed.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Health Burden of Hypophosphatasia
This completed trial assesses the health burden of hypophosphatasia. It outlines outcomes related to disease impact and patient burden.
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP) [Phase 2]
Phase 2 pharmacokinetic and dose–response study of asfotase alfa in adults with pediatric-onset hypophosphatasia completed; results posted i…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP) [Phase 2, Phase 3]
Open-label study of asfotase alfa in infants and children ≤5 years with hypophosphatasia completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP) [Phase 2]
Extension study update for asfotase alfa in infants and young children with hypophosphatasia (Phase 2) completed; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP) [Phase 2]
A Phase 2 trial evaluating safety and efficacy of asfotase alfa in adolescents and adults with hypophosphatasia has completed with results p…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP) [Phase 2]
Extension study update for asfotase alfa in children with hypophosphatasia (Phase 2) completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan [Phase 4]
This document reports results from a Phase 4 post-approval clinical study of asfotase alfa in Japanese patients with hypophosphatasia.
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Burden of Disease in Hypophosphatasia (HPP)
An update on the completed clinical trial NCT02291497 evaluating the burden of disease in hypophosphatasia, sponsored by Würzburg University…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Safety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP) [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of asfotase alfa in patients with hypophosphatasia has completed.
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)
Retrospective, non-interventional natural history study of juvenile-onset hypophosphatasia completed with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2011-09-30Clinical Trial Update: Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP) [Phase 1, Phase 2]
A Phase 1/2 safety and efficacy study of asfotase alfa in severely affected infants with hypophosphatasia has completed, with results posted…
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP) [Phase 2]
Phase 2 trial evaluating safety and efficacy of asfotase alfa in juvenile patients with hypophosphatasia has completed with results posted.