Hypophosphatasia
📧 Sign up to get email alerts when something new happens for Hypophosphatasia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: United States Hypophosphatasia Molecular Research Center
A United States clinical trial for hypophosphatasia remains active but not recruiting. The study is sponsored by Children's Mercy Hospital K…
-
CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia
AstraZeneca is conducting a clinical trial in Russia to assess how monoallelic ALPL gene variants affect the natural course of hypophosphata…
-
CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa [Phase 3]
Phase 3 study evaluating ALXN1850 in pediatric patients with hypophosphatasia who were previously treated with asfotase alfa; the trial is a…
-
CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Natural History Study of Patients With Hypophosphatasia (HPP)
ClinicalTrials.gov reports a natural history observational study of hypophosphatasia sponsored by Duke University, and the trial is currentl…
-
CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Registry of Patients With Hypophosphatasia
This is a patient registry for hypophosphatasia sponsored by Alexion Pharmaceuticals, with enrollment currently by invitation.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP [Phase 3]
Phase 3 trial of ALXN1850 in treatment-naïve pediatric participants with hypophosphatasia is currently not recruiting.
-
CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: A Prospective Sub-Study of the Global Hypophosphatasia Registry
A prospective sub-study within the Global Hypophosphatasia Registry is underway, sponsored by Alexion Pharmaceuticals, to collect data on in…
-
CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults With Hypophosphatasia in Order to Identify Suitable Doses of ALE1 [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of ALE1 in healthy adults and adult…
-
CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)
A prospective, longitudinal observational registry enrolling adults with hypophosphatasia to study disease course and outcomes.
-
CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study
A multi-center study led by the University of Bonn is characterizing adult hypophosphatasia in rheumatology patients to inform an algorithm …
-
CLINICAL_TRIALS research · 2015-09-28Clinical Trial Update: Non-interventional Substudy of ALX-HPP-502 to Assess Natural History of Patients With Juvenile-onset HPP Who Served as Historical Controls in ENB-006-09
Non-interventional substudy to assess natural history of juvenile-onset hypophosphatasia using historical controls from ENB-006-09; complete…
-
CLINICAL_TRIALS research · 2014-07-21Clinical Trial Update: A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)
A retrospective study analyzing the natural history of severe perinatal and infantile hypophosphatasia (HPP).