Hypoparathyroidism
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism [Phase 2]
Phase 2 trial evaluating MBX 2109 in hypoparathyroidism has completed, reporting safety, pharmacokinetics and efficacy data.
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidism [Phase 2]
Phase 2 trial update comparing pump-delivered PTH 1-34 with subcutaneous injections for chronic hypoparathyroidism; results from the study h…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous Forteo [Phase 1]
Phase 1 trial assessing safety and pharmacokinetics of new oral hPTH(1-34) tablet formulations, compared with EBP05 tablets and subcutaneous…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Palopegteriparatide in Chronic Hypoparathyroidism
This clinical trial update notes that the study evaluating Palopegteriparatide for chronic hypoparathyroidism has completed.
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism [Phase 3]
Phase 3 PaTHway CHINA trial evaluating safety, tolerability, and efficacy of TransCon PTH in adults with hypoparathyroidism has completed.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thyroidectomy
Completed clinical trial evaluating whether postoperative parathyroid hormone dosing can predict hypoparathyroidism after total thyroidectom…
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroidism [Phase 2]
An extension study is planned to evaluate the long-term safety and tolerability of MBX 2109 in patients with hypoparathyroidism. The trial i…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Evaluation of the Safety and Efficacy of Eneboparatide (AZP-3601) in Patients With Chronic Hypoparathyroidism [Phase 3]
Ongoing Phase 3 trial evaluating the safety and efficacy of Eneboparatide (AZP-3601) for chronic hypoparathyroidism. The study is currently …
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total Thyroidectomy [NA]
The trial evaluates near-infrared autofluorescence (NIRAF) for identifying parathyroid glands during total thyroidectomy and reports potenti…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Cardiovascular, Renal, and Skeletal Complications in Patients With Post-Surgical Hypoparathyroidism
This clinical trial update reports the completion of a study examining cardiovascular, renal, and skeletal complications in patients with po…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy [NA]
A completed clinical trial evaluating the benefits of near-infrared autofluorescence (NIRAF) detection to identify parathyroid glands during…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism [Phase 3]
Phase 3 trial evaluating safety, tolerability and efficacy of TransCon PTH in adults with hypoparathyroidism has completed with results post…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Near-infrared Imaging Techniques for Identifying and Preserving Viable Parathyroid Glands During Thyroidectomy [NA]
This completed clinical trial evaluated near-infrared imaging techniques to identify and preserve viable parathyroid glands during thyroidec…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Autofluorescence vs Clinical Assessment of Parathyroid Glands During Thyroid Surgery [NA]
This completed clinical trial compared autofluorescence-guided assessment of the parathyroid glands with standard clinical assessment during…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy. [NA]
A Vanderbilt-led trial evaluated near-infrared autofluorescence (NIRAF) detection to identify parathyroid glands during total thyroidectomy;…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Validation of a Hypoparathyroidism Self-questionnaire
A completed clinical trial validating a self-questionnaire for postoperative hypoparathyroidism after thyroidectomy. The study was sponsored…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: HEXT (Hypo EXTended): Effect of PTH on Skeleton in Hypoparathyroidism [Phase 3]
A Phase 3 study named HEXT assessed the effects of parathyroid hormone on skeletal health in hypoparathyroidism; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green Angiography
This clinical trial evaluated parathyroid vascularization during total thyroidectomy using indocyanine green angiography; the study status w…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: AZP-3601 SAD and MAD Study in Healthy Subjects and Patients With Hypoparathyroidism [Phase 1, Phase 2]
AZP-3601 completed single-ascending-dose and multiple-ascending-dose studies in healthy subjects and patients with hypoparathyroidism, with …
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CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism [Phase 2]
Phase 2 trial of TransCon PTH in adults with hypoparathyroidism has completed, with results posted in 2023 evaluating safety, tolerability, …
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE) [Phase 4]
Phase 4 trial assessing rhPTH(1-84) for symptom improvement and metabolic control in adults with hypoparathyroidism has completed with resul…
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CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: A Study of Extended Use of Recombinant Human Parathyroid Hormone (rhPTH(1-84)) in Hypoparathyroidism [Phase 4]
Phase 4 study evaluating extended use of rhPTH(1-84) in hypoparathyroidism has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-28Clinical Trial Update: Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazide in Severe Primary Hypoparathyroidism [Phase 2]
Phase 2 trial comparing recombinant human rhPTH(1-34) to alfacalcidol/hydrochlorothiazide in severe primary hypoparathyroidism with hypercal…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Safety and Efficacy Study of rhPTH(1-84) in Subjects With Hypoparathyroidism [Phase 3]
Phase 3 safety and efficacy study of rhPTH(1-84) in hypoparathyroidism was terminated.
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Study to Assess the Blood Concentrations and Actions of Recombinant Human Parathyroid Hormone (rhPTH [1-84]) When Given Once and Twice Daily to Participants With Hypoparathyroidism [Phase 1]
Phase 1 study assessing blood concentrations and actions of recombinant human parathyroid hormone (rhPTH 1-84) given once vs twice daily in …