Hypoparathyroidism
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EMA withdrawal · 2026-07-10EMA Withdrawn: Natpar (parathyroid hormone) — Takeda Pharmaceuticals International AG Ireland Branch
EU EMA has withdrawn Natpar (parathyroid hormone) by Takeda; therapeutic area hypoparathyroidism with previous conditional and orphan design…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism [Phase 3]
A Phase 3 randomized clinical trial is evaluating the safety and efficacy of Palopegteriparatide at doses greater than 30 μg/day in adults w…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: An Cohort Study on the Safety and Efficacy of XH-02 in Treating Hypoparathyroidism [Phase 2]
A Phase 2 cohort study to evaluate the safety and efficacy of XH-02 for hypoparathyroidism, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study to Assess the Amount of Palopegteriparatide in Breast Milk of Lactating Females Requiring YORVIPATH® (Palopegteriparatide)
This clinical trial update describes a study to measure how much palopegteriparatide is present in the breast milk of lactating women who re…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the efficacy and safety of subcutaneous XH-02 for adult hypoparathyroidism; currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Efficacy and Safety of XH02 for the Treatment of Hypoparathyroidism [EARLY_Phase 1]
This early-phase trial is evaluating the safety and preliminary efficacy of XH02 for hypoparathyroidism and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism [Phase 2]
Phase 2 trial evaluating MBX 2109 in hypoparathyroidism has completed, reporting safety, pharmacokinetics and efficacy data.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy [Phase 3]
A Phase 3 clinical trial evaluating the use of indocyanine green (ICG) angiography to identify parathyroid glands during total thyroidectomy…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidism [Phase 2]
Phase 2 trial update comparing pump-delivered PTH 1-34 with subcutaneous injections for chronic hypoparathyroidism; results from the study h…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Global Pregnancy Registry to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to YORVIPATH® (Palopegteriparatide) During Pregnancy and Breastfeeding
This clinical trial update describes a global pregnancy registry to collect maternal, fetal, and infant outcomes after exposure to YORVIPATH…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Parathyroid Allotransplant for Treatment of Hypoparathyroidism [Phase 1, Phase 2]
Clinical trial update for parathyroid allotransplant to treat hypoparathyroidism, currently in Phase 1/2 and recruiting. The trial seeks to …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous Forteo [Phase 1]
Phase 1 trial assessing safety and pharmacokinetics of new oral hPTH(1-34) tablet formulations, compared with EBP05 tablets and subcutaneous…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Effects of Total Thyroid Removal on Parathyroid Function and Quality of Life [NA]
Clinical trial update describing a study on the effects of total thyroid removal on parathyroid function and quality of life, currently enro…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Palopegteriparatide in Chronic Hypoparathyroidism
This clinical trial update notes that the study evaluating Palopegteriparatide for chronic hypoparathyroidism has completed.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Survey to Assess Participants' and Physicians' Knowledge, Attitudes and Behavior When Using NATPARA
A completed clinical trial that surveys participants and physicians about knowledge, attitudes, and behavior when using NATPARA for hypopara…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism [Phase 3]
Phase 3 PaTHway CHINA trial evaluating safety, tolerability, and efficacy of TransCon PTH in adults with hypoparathyroidism has completed.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Hypoparathyroidism Natural History Study
A natural history study of hypoparathyroidism sponsored by Columbia University is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total Thyroidectomy
Completed clinical trial evaluating whether postoperative parathyroid hormone dosing can predict hypoparathyroidism after total thyroidectom…
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroidism [Phase 2]
An extension study is planned to evaluate the long-term safety and tolerability of MBX 2109 in patients with hypoparathyroidism. The trial i…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Evaluation of the Safety and Efficacy of Eneboparatide (AZP-3601) in Patients With Chronic Hypoparathyroidism [Phase 3]
Ongoing Phase 3 trial evaluating the safety and efficacy of Eneboparatide (AZP-3601) for chronic hypoparathyroidism. The study is currently …
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: A Registry for Participants With Chronic Hypoparathyroidism
Takeda is updating a registry for participants with chronic hypoparathyroidism; the study is active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Translation and Validation of the Hypoparathyroidism Patient Experience Scales (HPES) Questionnaire in Greek
This clinical trial involves translating and validating the Hypoparathyroidism Patient Experience Scales (HPES) into Greek.
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adults [Phase 2]
A Phase 2 clinical trial evaluating AMOR-1 for treating hypocalcemia associated with hypoparathyroidism is currently recruiting in adults.
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial. [NA]
A parallel randomized controlled trial comparing the PTeye device to the surgeon's eyes for intraoperative identification and functional pre…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism [Phase 4]
A Phase 4 trial is evaluating indapamide for post-surgical hypoparathyroidism and is currently recruiting.