Hyponatremia
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Hyponatremia in the Elderly: Benefit From a Change in Drug Therapy? [NA]
Clinical trial update evaluating whether changing drug therapy benefits elderly patients with hyponatremia. The study status is completed.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Retrospective Analysis of ECG Changes and Arrhythmias in Patients With Profound Hyponatremia
This retrospective analysis examines electrocardiogram changes and arrhythmias in patients with profound hyponatremia. The study, sponsored …
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients
A clinical trial conducted in hospitalized patients investigates how serum sodium levels influence bone metabolism and turnover; the study s…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Phase 2a Study for PK/PD of nC-001 [Phase 2]
A Phase 2a PK/PD study of nC-001 for chronic hyponatremia is planned, with recruitment not yet started.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD [NA]
A completed clinical trial evaluating intravenous [Pyr1]Apelin-13 in healthy volunteers with artificially induced SIAD, focusing on effects …
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Asymptomatic Bacteriuria, Hyponatremia and Geri-atric Syndrome [NA]
This is a completed clinical trial update from Universitair Ziekenhuis Brussel examining asymptomatic bacteriuria in the context of hyponatr…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Delirium Related to Proton Pump Inhibitors Use
This completed trial evaluated delirium associated with proton pump inhibitor use and related hyponatremia as an adverse event.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia [Phase 2]
Phase 2 trial evaluating the efficacy and safety of Tolvaptan tablets in patients with hypovolemic hyponatremia; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Samsca Post-marketing General Drug Use-results Survey in Patients with Hyponatremia in SIADH
This clinical trial update discusses a post-marketing general drug use-results survey evaluating tolvaptan (Samsca) for hyponatremia associa…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Albumin for Management of Hypervolemic Hyponatremia (AlbuCAT) [Phase 2]
Phase 2 trial (AlbuCAT) evaluating albumin for management of hypervolemic hyponatremia in patients with cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Mortality and Neurologic Outcomes in Rapid vs. Slow Hyponatremia Correction
This completed clinical trial evaluated mortality and neurologic outcomes in rapid versus slow correction of hyponatremia to assess safety a…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) [NA]
This completed clinical trial evaluated delayed hyponatremia after pituitary surgery.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery [NA]
This completed clinical trial compared isotonic and hypotonic fluids for maintenance fluid therapy in neonates after surgery.
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Urea for Chronic Hyponatremia [Phase 2]
Phase 2 trial evaluating urea for chronic hyponatremia was terminated. Results were posted on 2024-05-20.
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Colloid Osmotic Pressure and Osmolality in Hyponatremia
The clinical trial evaluating colloid osmotic pressure and osmolality in hyponatremia has been terminated.
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CLINICAL_TRIALS trial_result · 2021-12-13Clinical Trial Update: Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study [Phase 2, Phase 3]
Phase 2/3 trial evaluating empagliflozin for SIADH-related hyponatremia has completed.
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium [Phase 1, Phase 2]
A clinical trial update on cicletanine in hypertension with diabetes discusses added magnesium to preserve potassium and sodium, spanning Ph…
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CLINICAL_TRIALS trial_result · 2020-07-27Clinical Trial Update: Tolvaptan for Advanced or Refractory Heart Failure [Phase 4]
A Phase 4 clinical trial of tolvaptan for advanced or refractory heart failure has been terminated.
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CLINICAL_TRIALS trial_result · 2020-04-17Clinical Trial Update: An Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Participants With Euvolemic or Hypervolemic Hyponatremia [Phase 3]
Phase 3 extension trial evaluating long-term safety in children and adolescents with euvolemic or hypervolemic hyponatremia; the study statu…
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Rapid Intermittent Compared With Slow Continuous Correction in Severe Hyponatremia Patients [Phase 4]
Phase 4 trial update evaluating efficacy and safety of rapid intermittent correction versus slow continuous correction in symptomatic hypona…
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CLINICAL_TRIALS trial_result · 2020-04-08Clinical Trial Update: Early Sodium Intake in Preterm Newborns [Phase 4]
Phase 4 clinical trial update on early sodium intake in preterm newborns completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-08-22Clinical Trial Update: Intravenous Fluids in Hospitalised Children [Phase 4]
A Phase 4 trial update on intravenous fluids in hospitalized children completed, investigating safety or efficacy related to electrolyte imb…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Fluid Tonicity and Hyponatraemia Post Surgery
A completed clinical trial evaluating the effect of fluid tonicity on hyponatremia after surgery. The study is sponsored by National Univers…
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Study of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia [Phase 3]
Phase 3 pediatric trial of tolvaptan (SAMSCA) for hyponatremia was terminated; results were posted.
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CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: Regional Tolvaptan Registry [Phase 4]
Phase 4 trial update for a regional registry evaluating tolvaptan in patients with decompensated heart failure and hyponatremia.