Hypertrophic Cardiomyopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Effect of Henagliflozin on Myocardial Fibrosis in Non-Obstructive HCM: A Randomized, Double-Blind, Placebo-Controlled Trial Using 68Ga/18F-FAPI PET/CMR [NA]
A randomized, double-blind, placebo-controlled trial of Henagliflozin for myocardial fibrosis in non-obstructive hypertrophic cardiomyopathy…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Ongoing Phase 3 trial of mavacamten in adolescents with symptomatic obstructive hypertrophic cardiomyopathy; the study is currently not recr…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: ReGistry of hypeRtrophic cArDIomyopathy: Regional fEatures, geNeTics and Course
Registry-style clinical trial update for hypertrophic cardiomyopathy focusing on regional features, genetics, and disease course; currently …
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study [NA]
NHLBI's SESAME early feasibility trial evaluating septal scoring along the midline endocardium in hypertrophic cardiomyopathy and related va…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: REFINE-HCM: Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy [NA]
A clinical trial update for REFINE-HCM evaluating intramyocardial septal radiofrequency ablation to treat obstructive hypertrophic cardiomyo…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Austrian Hypertrophic Cardiomyopathy Registry
The Austrian Hypertrophic Cardiomyopathy Registry is an ongoing clinical study led by the Medical University of Graz and currently recruitin…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: AI-Enabled Diagnosis and Prognosis of Hypertrophic Cardiomyopathy
An ongoing study sponsored by Zhejiang University aims to develop AI-based methods for diagnosing and forecasting outcomes in hypertrophic c…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy [NA]
A UCSF-sponsored clinical trial on exercise intolerance in non-obstructive hypertrophic cardiomyopathy is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: A Trial of HRS-1893 in Healthy Volunteers [EARLY_Phase 1]
An early Phase 1 trial of HRS-1893 in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 study of mavacamten for non-obstructive hypertrophic cardiomyopathy has completed.
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
A Columbia University-led clinical trial is recruiting to analyze lumbar spine stenosis specimens for identification of transthyretin-relate…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Mavacamten Pregnancy Surveillance Program
This ClinicalTrials.gov entry describes a mavacamten pregnancy surveillance program to monitor safety and outcomes in people with hypertroph…
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EMA approval · 2025-10-23EMA Authorised: Camzyos (Mavacamten) — Bristol-Myers Squibb Pharma EEIG
The European Medicines Agency authorised Camzyos (mavacamten) for hypertrophic cardiomyopathy, with Bristol-Myers Squibb Pharma EEIG as the …
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: LA-HCM Study : Rivaroxaban for Antithrombotic Prevention in Hypertrophic Cardiomyopathy Patients With Abnormal Left Atrial Strain. [Phase 3]
A Phase 3 clinical trial evaluating rivaroxaban for antithrombotic prevention in hypertrophic cardiomyopathy patients with abnormal left atr…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy [Phase 2]
This Phase 2 trial evaluated the efficacy and potential mechanism of trientine in patients with hypertrophic cardiomyopathy and has complete…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 4]
Phase 4 clinical trial update for mavacamten in symptomatic obstructive hypertrophic cardiomyopathy; the study is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Intraventricular Stasis In Cardiovascular Disease
A completed clinical trial update on intraventricular stasis in cardiovascular disease. The study involves patients with dilated cardiomyopa…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Safety and Pharmacokinetics Study of HRS-1893 Tablets in Healthy Subjects and Those With Impaired Kidney Function [Phase 1]
Phase 1 safety and pharmacokinetics study of HRS-1893 tablets in healthy subjects and those with impaired kidney function has completed.
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Clinical Study to Evaluate the Long-term Safety of HRS-1893 in Hypertrophic Cardiomyopathy [Phase 2]
Clinical trial update indicates a Phase 2 long-term safety study of HRS-1893 for hypertrophic cardiomyopathy is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Stratification, Management, and Guidance of Hypertrophic Cardiomyopathy Patients Using Hybrid Digital Twin Solutions
A clinical trial exploring how hybrid digital twin technology can help stratify risk and guide management for hypertrophic cardiomyopathy; t…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
A University of Edinburgh-led clinical trial update describing a recruiting study that uses cardiac imaging to evaluate myocardial fibrosis …
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: VIZ ACCESS HCM - Multi-Site Registry
A multi-site registry study called VIZ ACCESS HCM sponsored by Viz.ai, Inc. is currently recruiting participants with Hypertrophic Cardiomyo…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Effect of an Aerobic Exercise Session on Cardiovascular and Autonomic Parameters of Adults With Hypertrophic Cardiomyopathy [NA]
A clinical trial is examining how a single aerobic exercise session affects cardiovascular and autonomic parameters in adults with hypertrop…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 trial evaluating MYK-224 for symptomatic obstructive hypertrophic cardiomyopathy has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: A Study to Assess Health-Related Quality of Life in Patients With Hypertrophic Cardiomyopathy in Japan
A completed clinical trial conducted in Japan assessed health-related quality of life in patients with hypertrophic cardiomyopathy.