Hypertrophic Cardiomyopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM [Phase 2, Phase 3]
This clinical trial update notes the completion of a long-term safety extension study of mavacamten in adults who completed MAVERICK-HCM or …
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Pilot Study of Hypertrophic Cardiomyopathy & Implantable Cardioverter Defibrillator Assessment: (Subcutaneous vs Transvenous) [NA]
A pilot trial comparing subcutaneous versus transvenous implantable cardioverter-defibrillators in patients with hypertrophic cardiomyopathy…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Study of the Progression of Chronic Cardiovascular Conditions
Clinical trial is currently recruiting to study the progression of chronic cardiovascular conditions, including heart failure, hypertension,…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Retrospective Natural History Study of RASopathy-associated Cardiomyopathy (RAS-CM)
A retrospective natural history study of RASopathy-associated cardiomyopathy (RAS-CM) is sponsored by Deutsches Herzzentrum Muenchen and cur…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy
This clinical trial update describes a study on precision pharmacogenetics and genotype-based prediction of mavacamten response in obstructi…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy [EARLY_Phase 1]
Early-phase clinical trial evaluating sodium-glucose cotransporter (SGLT) inhibitors for nonobstructive hypertrophic cardiomyopathy; recruit…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Effect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic Cardiomyopathy [NA]
A clinical trial evaluating personalized accelerated pacing in symptomatic non-obstructive hypertrophic cardiomyopathy has been terminated.
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FDA approval · 2026-02-05FDA Approved: MYQORZO — Supplemental Application (Cytokinetics Inc.)
FDA approved a supplemental application for MYQORZO (aficamten) from Cytokinetics Inc. This action authorizes changes associated with the dr…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy
This update describes a prospective incident study of arrhythmias in hypertrophic cardiomyopathy, sponsored by Mayo Clinic. The trial is cur…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM [Phase 3]
A Phase 3 trial evaluating Aficamten versus placebo for symptomatic non-obstructive hypertrophic cardiomyopathy is ongoing but not currently…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes
A recruiting clinical trial evaluating myocardial perfusion cardiac MRI to differentiate and characterize hypertrophic cardiomyopathy phenot…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Multicentre Hypertrophic Cardiomyopathy Registry
A multicentre registry study for hypertrophic cardiomyopathy is listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After Myectomy [NA]
A ClinicalTrials.gov update shows a recruiting study evaluating left bundle branch pacing in patients with hypertrophic cardiomyopathy after…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: One-stop Evaluation of Hypertrophic Cardiomyopathy in Cardiac Magnetic Resonance
This entry reports an ongoing clinical study titled 'One-stop Evaluation of Hypertrophic Cardiomyopathy in Cardiac Magnetic Resonance,' spon…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM [Phase 2, Phase 3]
Open-label extension study to assess the long-term safety and tolerability of aficamten in adults with hypertrophic cardiomyopathy. The tria…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Multimodal Analysis of Endomyocardial Biopsies
A recruiting clinical study from University Hospital, Essen, investigates multimodal analysis of endomyocardial biopsies across several card…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: The Application of T1 Mapping in Real-World
A real-world study evaluating the use of T1 mapping in patients with myocardial infarction, hypertrophic cardiomyopathy, dilated cardiomyopa…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Automated Reports Generation of Cardiovascular Magnetic Resonance Imaging
Update on a study evaluating automated report generation for Cardiovascular Magnetic Resonance imaging in hypertrophic cardiomyopathy; the t…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: The Therapeutic Value of Mavacamten in Hypertrophic Cardiomyopathy With Mid-to-Apical Left Ventricular Obstruction [Phase 4]
This Phase 4 clinical trial update evaluates mavacamten for hypertrophic cardiomyopathy with mid-to-apical left ventricular obstruction. The…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
This clinical trial update notes enrollment by invitation for a Johns Hopkins study deriving human induced pluripotent stem cells to model h…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Institutional Registry of Rare Diseases
An institutional registry for rare diseases sponsored by Hospital Italiano de Buenos Aires is currently recruiting. The registry includes am…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Myocardial Energetic Restoration in the Treatment of Obstructive Hypertrophic Cardiomyopathy
A clinical trial investigating myocardial energetic restoration for obstructive hypertrophic cardiomyopathy is not yet recruiting (sponsored…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry
A multicenter registry in Brazil's public health system aims to improve care for hereditary cardiovascular diseases by enrolling patients ac…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Mavacamten Enables Exercise in Hypertrophic Obstructive Cardiomyopathy [NA]
A clinical trial is evaluating mavacamten for patients with hypertrophic cardiomyopathy with obstructive features to assess its effect on ex…
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FDA approval · 2025-12-19FDA Approved: MYQORZO — Original Application (Cytokinetics Inc.)
The FDA approved MYQORZO (aficamten) from Cytokinetics as an original-application approval for the treatment of symptomatic obstructive hype…