Hypertriglyceridemia
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) [Phase 3]
Phase 3 trial evaluating AMR101 (ethyl icosapentate) on triglyceride levels in patients with hypertriglyceridemia on statins; study complete…
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL [Phase 3]
Phase 3 trial results for AMR101 (ethyl esters of eicosapentaenoic acid) in patients with fasting triglycerides 500–2000 mg/dL; study comple…
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CLINICAL_TRIALS trial_result · 2022-04-13Clinical Trial Update: The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia [Phase 3]
A Phase 3 trial in hypertriglyceridemia assessing volanesorsen (ISIS-APOCIIIRx) has completed; results were posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-03-04Clinical Trial Update: Pharmacodynamic Effects of a Free-Fatty Acid Formulation of Omega-3 Pentaenoic Acid in Adults With Hypertriglyceridemia [Phase 2]
Phase 2 trial evaluating pharmacodynamic effects of a free-fatty acid formulation of omega-3 pentaenoic acid in adults with hypertriglycerid…
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CLINICAL_TRIALS trial_result · 2022-01-27Clinical Trial Update: Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia [Phase 2]
Phase 2 safety, tolerability, and pharmacokinetic study of ISIS ApoC-III Rx in hypertriglyceridemia has completed.
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CLINICAL_TRIALS trial_result · 2022-01-04Clinical Trial Update: Setmelanotide in a Single Patient With Partial Lipodystrophy [Phase 2]
Phase 2 clinical trial update reporting on a single patient treated with setmelanotide for partial lipodystrophy.
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CLINICAL_TRIALS trial_result · 2021-12-22Clinical Trial Update: A Study to Evaluate the Effect of GFA-918 on Serum Triglyceride Levels in Individuals With Elevated Serum Triglyceride [Phase 2]
A Phase 2 clinical trial evaluating the effect of GFA-918 on serum triglyceride levels in individuals with elevated triglycerides has comple…
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CLINICAL_TRIALS trial_result · 2021-12-10Clinical Trial Update: Evaluation of Common Bean Baked Snack Consumption on Blood Lipids in Overweight People With Altered Blood Lipid Levels [Phase 2]
Phase 2 clinical trial evaluating common bean baked snack consumption on blood lipid levels in overweight individuals with dyslipidemia; stu…
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy [Phase 4]
Phase 4 trial updating on the effect of Vascepa (icosapent ethyl) on improving coronary atherosclerosis in people with high triglycerides on…
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: The Effect of Fish Oil Plus Fenofibrate on Triglyceride Levels in People Taking Highly Active Antiretroviral Therapy (HAART) [Phase 2]
Phase 2 trial evaluating the effect of fish oil plus fenofibrate on triglyceride levels in people on HAART.
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Niacin, N-3 Fatty Acids and Insulin Resistance [Phase 4]
Phase 4 clinical trial evaluating effects of niacin and n-3 fatty acids on insulin resistance in metabolic syndrome and hypertriglyceridemia…
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CLINICAL_TRIALS trial_result · 2021-10-20Clinical Trial Update: Effects of Lovaza on Lipoprotein Composition and Function in Mild Hypertriglyceridemia [Phase 1, Phase 2]
Clinical trial update on the effects of Lovaza on lipoprotein composition and function in mild hypertriglyceridemia (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2021-08-23Clinical Trial Update: Long-term Safety and Efficacy Study of MND-2119 in Patients With Hypertriglyceridemia [Phase 3]
Phase 3 trial update reporting long-term safety and efficacy of MND-2119 in patients with hypertriglyceridemia.
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CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia [Phase 3]
Phase 3 outcomes study completed; FocaSThStatin residual risk reduction with EPA in high cardiovascular risk patients with hypertriglyceride…
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CLINICAL_TRIALS trial_result · 2021-06-15Clinical Trial Update: Fructose Consumption and Metabolic Dysregulation [NA]
Completed clinical trial studying fructose consumption and metabolic dysregulation in adults with central obesity and hypertriglyceridemia; …
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: An Efficacy and Safety Study of Omega-3-acid Ethyl Ester in Chinese Subjects With Hypertriglyceridemia. [Phase 3]
Phase 3 study reporting efficacy and safety of Omega-3-acid Ethyl Ester in Chinese adults with hypertriglyceridemia; study completed.
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CLINICAL_TRIALS trial_result · 2021-02-01Clinical Trial Update: Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease [Phase 2]
Phase 2 study of ISIS 703802 in participants with hypertriglyceridemia, type 2 diabetes, and nonalcoholic fatty liver disease has completed …
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia [Phase 1, Phase 2]
Clinical trial update assessing safety, tolerability, PK, and PD of LCQ908 in patients with severe hypertriglyceridemia across Phase 1 and P…
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: A Prospective Observational Program Using Digital Technology Tools to Enhance Patient Adherence to Omacor Therapy
Observational clinical trial assessing use of digital tools to improve adherence to Omacor therapy in patients with previous myocardial infa…
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules [Phase 1, Phase 2]
Clinical trial update for two omega-3 capsule formulations; Phase 1/2 study completed in hypertriglyceridemia.
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CLINICAL_TRIALS trial_result · 2020-10-05Clinical Trial Update: Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes [Phase 2, Phase 3]
Phase 2/3 trial update for Totum-63 (Valedia) assessing effects on glucose and lipid homeostasis in prediabetes and related metabolic condit…
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CLINICAL_TRIALS trial_result · 2020-08-17Clinical Trial Update: Study of Gemcabene in Adults With FPLD [Phase 1, Phase 2]
Phase 1/2 trial updates for gemcabene in adults with familial partial lipodystrophy (FPLD) and hypertriglyceridemia have been completed with…
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CLINICAL_TRIALS trial_result · 2020-08-12Clinical Trial Update: A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2) [Phase 3]
Phase 3 trial update for CaPRe in lowering very high triglycerides (TRILOGY 2) has completed.
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CLINICAL_TRIALS trial_result · 2020-06-25Clinical Trial Update: A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia [Phase 2]
Phase 2 clinical trial evaluating gemcabene for efficacy, safety, and tolerability in adults with severe hypertriglyceridemia (completed; re…
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides [Phase 2]
Phase 2 trial update assessing efficacy and safety of gemcabene in patients with low HDL-C and varying triglyceride levels; study completed.