Hypertriglyceridemia
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CLINICAL_TRIALS trial_result · 2026-08-06Clinical Trial Update: Study of Plozasiran in Adults With Severe Hypertriglyceridemia [Phase 3]
Phase 3 clinical trial update for Plozasiran in adults with severe hypertriglyceridemia.
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CLINICAL_TRIALS trial_result · 2026-07-15Clinical Trial Update: Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia [Phase 3]
Phase 3 trial of Plozasiran (ARO-APOC3) in adults with severe hypertriglyceridemia is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-07-07Clinical Trial Update: To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia [Phase 3]
Phase 3 trial update assessing efficacy and safety of pegozafermin in adults with severe hypertriglyceridemia completed.
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CLINICAL_TRIALS trial_result · 2026-06-26Clinical Trial Update: Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia [Phase 3]
Phase 3 clinical trial update for Plozasiran in adults with hypertriglyceridemia. Status is active not recruiting.
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Update: To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of pegozafermin in subjects with severe hypertriglyceridemia has completed.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia [Phase 2]
Phase 2 study of olezarsen (formerly AKCEA-APOCIII-LRx) in adults with hypertriglyceridemia and atherosclerotic cardiovascular disease or se…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: First-in-Human Study of ISH0688: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics [Phase 1]
First-in-human Phase 1 trial of ISH0688 evaluates safety, tolerability, pharmacokinetics, and pharmacodynamics in healthy subjects and indiv…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia [Phase 2]
Phase 2 study evaluating ARO-APOC3 in adults with Severe Hypertriglyceridemia has completed and posted results.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Long-term Comparison of Pitavastatin/Ezetimibe and Pitavastatin in Patients With Hypercholesterolemia and Elevated Triglycerides [Phase 4]
Phase 4 trial comparing long-term outcomes of pitavastatin/ezetimibe versus pitavastatin alone in patients with hypercholesterolemia and ele…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia [Phase 3]
Phase 3 clinical trial of olezarsen (ISIS 678354) in participants with hypertriglyceridemia and atherosclerotic cardiovascular disease, or w…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia [Phase 3]
Ionis Pharmaceuticals reports that the Phase 3 trial of olezarsen (ISIS 678354) in adults with severe hypertriglyceridemia has completed. Th…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Comparison of Cardiometabolic Markers in Individuals With Hypertriglyceridemia With Low and High Weight Loss Responses to an Energy-restricted Diet [NA]
The study compared cardiometabolic markers in individuals with hypertriglyceridemia who had low versus high weight loss responses to an ener…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Rosemary Infusion for Hypertension With Hypertriglyceridemia [NA]
A clinical trial evaluating rosemary infusion for hypertension with hypertriglyceridemia has completed.
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: A Phase II Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe Hypertriglyceridemia [Phase 2]
Phase II clinical trial of DR10624 for severe hypertriglyceridemia has completed; the snippet provides no efficacy or safety results.
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Study of RN0361in Adult Healthy Subjects and Adult Hypertriglyceridemic Subjects [Phase 1, Phase 2]
RN0361 is being studied in healthy adults and adults with hypertriglyceridemia (including familial chylomicronemia syndrome) in Phase 1 and …
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS) [Phase 1]
Phase 1 study evaluating ARO-APOC3 in healthy volunteers and patients with hypertriglyceridemia or familial chylomicronemia syndrome has com…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients [Phase 1]
Phase 1 study of ARO-ANG3 in healthy volunteers and dyslipidemic patients has completed; the update provides status of the trial.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists [Phase 2]
Phase 2 trial evaluating RDX-002's effect on postprandial triglycerides in patients discontinuing GLP-1 agonists; study completed.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Cipros 10 Association for isolated hypertriglyceridemia and dyslipidemia has completed.
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Study of MAR001 in Adults With Metabolic Dysfunction [Phase 1, Phase 2]
A clinical trial of MAR001 in adults with metabolic dysfunction focusing on hypertriglyceridemia has completed Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia [Phase 3]
Phase 3 trial of olezarsen administered subcutaneously in adults with severe hypertriglyceridemia has completed.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Response to an Intervention With Omega-3 (RIO - Study) [NA]
This document provides a status update on a completed clinical trial (RIO - Study) evaluating an Omega-3 intervention for individuals who ar…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers [Phase 1]
Phase 1 clinical trial update reports completion of a Phase 1 study of VSA003 in Chinese adult healthy volunteers.
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Efficacy and Safety of EzetimiBe/Rosuvastatin in Diabetic Dislipidemia With Hypertriglyceridaemia [Phase 4]
A Phase 4 clinical trial evaluating the efficacy and safety of the ezetimibe/rosuvastatin combination (EzetimiBe/Rosuvastatin) in patients w…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of pegozafermin in individuals with severe hypertriglyceridemia; the study is curr…