Hyperlipoproteinemia
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CLINICAL_TRIALS trial_result · 2026-07-17Clinical Trial Results: A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany [Phase 3]
Phase 3 multicenter trial evaluating lipoprotein(a) lowering with pelacarsen (TQJ230) on weekly lipoprotein apheresis sessions in patients w…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of DII235 in Adults With Elevated Lipoprotein(a) [Phase 2]
Phase 2 study evaluating DII235 in adults with elevated lipoprotein(a) to assess safety and preliminary efficacy; currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: A Study of HRS-5632 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events [Phase 2]
Phase 2 study evaluating HRS-5632 in adults with elevated lipoprotein(a) at high risk for cardiovascular events; the trial is currently acti…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Clinical Trial On The Effect Of Artisterol On Risk Factors In Individuals With Suboptimal Cholesterol Levels [NA]
A Zentiva-sponsored clinical trial is investigating the effects of Artisterol on cardiovascular risk factors in people with suboptimal chole…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: A Study of SRSD216 in Patients With Elevated Lipoprotein (a) [Phase 1, Phase 2]
This document notes a Phase 1/2 clinical trial of SRSD216 for elevated lipoprotein (a), currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: A Study of HRS-5346 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events [Phase 2]
Phase 2 study evaluating HRS-5346 in adults with elevated lipoprotein(a) at high cardiovascular risk has completed.
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) [Phase 3]
Open-label extension study to assess long-term safety and tolerability of Pelacarsen (TQJ230) in hyperlipoproteinemia(a) patients; Phase 3, …
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies. [Phase 3]
A Phase 3 trial evaluating Obicetrapib in patients with familial hypercholesterolemia on maximally tolerated lipid-modifying therapy has com…
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: A Study of LY3819469 in Participants With Elevated Lipoprotein(a) [Lp(a)] [Phase 2]
Phase 2 study of LY3819469 in participants with elevated lipoprotein(a) has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events [Phase 2]
Phase 2 trial of LY3473329 in adults with elevated lipoprotein(a) at high risk for cardiovascular events has completed and results have been…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: A Study of LY3561774 in Participants With Mixed Dyslipidemia [Phase 2]
Phase 2 study of LY3561774 in participants with mixed dyslipidemia completed; trial results have been posted.
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany [Phase 3]
Phase 3 multicenter trial evaluating whether lowering lipoprotein(a) with pelacarsen (TQJ230) reduces weekly lipoprotein(a) apheresis sessio…
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CLINICAL_TRIALS research · 2024-09-24Clinical Trial Update: The Prevalence of Hyper-Lp(a)-Emia in the PMMHRI-Lp(a) Registry
This clinical trial is investigating how common Hyperlipoproteinemia(a) is in the PMMHRI-Lp(a) Registry; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2024-02-22Clinical Trial Update: Dietary Effects on Lipoproteins and Thrombogenic Activity [Phase 3]
A Phase 3 clinical trial evaluating the impact of dietary patterns on lipoproteins and thrombogenic activity in cardiovascular conditions ha…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia [Phase 1, Phase 2]
Clinical trial update assessing safety, tolerability, PK, and PD of LCQ908 in patients with severe hypertriglyceridemia across Phase 1 and P…
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CLINICAL_TRIALS trial_result · 2016-10-14Clinical Trial Update: Plasma Triglyceride Lipolysis in Multifactorial Chylomicronemia
This clinical trial update reports the completed status of a study investigating plasma triglyceride lipolysis in multifactorial chylomicron…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Lipid Research Clinics Population Studies
NHLBI-sponsored Lipid Research Clinics Population Studies trial has completed, focusing on cardiovascular diseases and lipid-related conditi…
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: Safety and Efficacy of the DALI LDL-adsorber and MONET Lipoprotein Filter
Clinical trial update reporting safety and efficacy results for the DALI LDL-adsorber and MONET Lipoprotein Filter in patients with familial…
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CLINICAL_TRIALS withdrawal · 2015-06-04Clinical Trial Update: Randomized Controlled Trial of Lipid Apheresis in Patients With Elevated Lipoprotein(a) [NA]
This randomized controlled trial evaluating lipid apheresis for patients with elevated lipoprotein(a) and progressive cardiovascular disease…
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Effect of Niacin/Laropiprant on Postprandial Lipoprotein Metabolism in Patients With Dyslipoproteinemia [Phase 4]
Phase 4 trial evaluating the effect of Niacin/Laropiprant on postprandial lipoprotein metabolism in patients with dyslipoproteinemia was ter…
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CLINICAL_TRIALS research · 2013-08-23Clinical Trial Update: The Effects of Coenzyme A Combined With Statin on Serum Lipids in Patients With Hyperlipidemia [Phase 2, Phase 3]
A clinical trial is evaluating the combination of Coenzyme A with a statin to improve serum lipid levels in hyperlipoproteinemia, currently …
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CLINICAL_TRIALS trial_result · 2013-06-14Clinical Trial Update: Comparison of Coenzyme A and Fenofibrate for Safety and Efficacy On Patients With Hyperlipidemia [Phase 3]
Phase 3 clinical trial comparing Coenzyme A to Fenofibrate for safety and efficacy in patients with hyperlipoproteinemia has completed.
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CLINICAL_TRIALS trial_result · 2013-03-15Clinical Trial Update: Comparison of Coenzyme A and Pantethine Capsule for Safety and Efficacy On Patients With Hyperlipidemia [Phase 3]
Phase 3 clinical trial comparing Coenzyme A and Pantethine Capsule for safety and efficacy in hyperlipoproteinemia has completed.
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CLINICAL_TRIALS trial_result · 2012-07-19Clinical Trial Update: The Effects of Coenzyme A on Serum Lipids in Patients With Hyperlipidemia [Phase 2]
A Phase 2 clinical trial evaluating the effects of coenzyme A on serum lipids in patients with hyperlipoproteinemia has completed.
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CLINICAL_TRIALS trial_result · 2010-01-27Clinical Trial Update: A Study Comparing the Mechanisms of Action of Lifibrol and Pravastatin [Phase 3]
Phase 3 trial comparing Lifibrol and Pravastatin in patients with hypercholesterolemia and hyperlipoproteinemia has completed. The document …