Hypercholesterolemia

• CLINICAL_TRIALS research · 2025-08-22
  Clinical Trial Update: Effects of a Digital Health Application (Lipodia) on LDL-cholesterol Levels [NA]

  A clinical trial is investigating the effect of the Lipodia digital health application on LDL-cholesterol levels in individuals with hyperch…

• CLINICAL_TRIALS research · 2025-08-14
  Clinical Trial Update: Guideline Oriented Approach To Lipid Lowering In Asia-Pacific [NA]

  A clinical trial in the Asia-Pacific region evaluating guideline-oriented lipid-lowering strategies for patients with cardiovascular disease…

• CLINICAL_TRIALS trial_result · 2025-08-13
  Clinical Trial Update: Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. [Phase 3]

  Phase 3 results assess the efficacy and safety of Inclisiran as monotherapy in patients with primary hypercholesterolemia not receiving lipi…

• CLINICAL_TRIALS trial_result · 2025-08-08
  Clinical Trial Update: A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1) [Phase 2]

  A Phase 2 pediatric trial evaluating once-daily oral bempedoic acid in children aged 6 to 17 with heterozygous familial hypercholesterolemia…

• CLINICAL_TRIALS research · 2025-08-08
  Clinical Trial Update: Whey Protein Comparisons for Blood Lipid Effects [NA]

  This clinical trial update describes a whey protein study evaluating effects on blood lipids and it is currently recruiting.

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• CLINICAL_TRIALS other · 2025-08-07
  Clinical Trial Update: A Study to Evaluate the Effectiveness and Safety of Fixed-Dose Combination of Pitavastatin/ Ezetimibe

  A clinical trial update for a fixed-dose combination tablet of pitavastatin and ezetimibe; the study is currently recruiting to evaluate eff…

• CLINICAL_TRIALS trial_result · 2025-07-31
  Clinical Trial Update: The Benefits of the Measureof Epicardial Adipose Tissue During Coronary Calcium Assessment of the Refine Cardiovascular Risk Assessment at Reunion Island.

  This completed clinical study evaluated whether measuring epicardial adipose tissue alongside coronary calcium scoring improves refinement o…

• CLINICAL_TRIALS trial_result · 2025-07-29
  Clinical Trial Update: Efficacy and Safety of Atorvastatin and Ezetimibe (10/10mg) Fixed Dose Combination Versus Atorvastatin (20mg) Monotherapy in Bangladeshi Population [Phase 4]

  Phase 4 clinical trial in Bangladesh comparing atorvastatin/ezetimibe fixed-dose combination (10/10 mg) to atorvastatin 20 mg monotherapy fo…

• CLINICAL_TRIALS trial_result · 2025-07-28
  Clinical Trial Update: Effects of a Chilean Diet Supplemented With Gevuina Avellana on Lipid Profile in Humans With Hypercholesterolemia [NA]

  A clinical trial from Universidad de Concepcion evaluated the effect of a Chilean diet supplemented with Gevuina Avellana on lipid profiles …

• CLINICAL_TRIALS research · 2025-07-24
  Clinical Trial Update: Pharmacokinetics and Pharmacodynamics Study [Phase 1]

  Qilu Pharmaceutical is conducting a Phase 1 pharmacokinetics and pharmacodynamics study for a hyperlipidemia program; the trial is not yet r…

• CLINICAL_TRIALS trial_result · 2025-07-16
  Clinical Trial Update: Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Cholesterol Levels [Phase 4]

  Phase 4 trial comparing rosuvastatin to switching protease inhibitors in people with HIV and high cholesterol; results have been posted.

• FDA approval · 2025-06-26
  FDA Approved: PRAVASTATIN SODIUM — Supplemental Application (Dr.Reddy's Laboratories Limited)

  FDA approved a supplemental application for pravastatin sodium from Dr. Reddy's Laboratories Limited. This pertains to a generic pravastatin…

• CLINICAL_TRIALS trial_result · 2025-06-24
  Clinical Trial Update: Study of SHR-1209 Administered by Single-site or Multiple-site Subcutaneous Injections in Healthy Volunteers [Phase 1]

  Phase 1 trial evaluating safety and pharmacokinetics of SHR-1209 administered by single-site or multi-site subcutaneous injections in health…

• CLINICAL_TRIALS trial_result · 2025-06-12
  Clinical Trial Update: To Evaluate the Safety and Pharmacokinetic Characteristics of AJU-C711 in Healthy Adults [Phase 1]

  A Phase 1 clinical trial update evaluating the safety and pharmacokinetic characteristics of AJU-C711 in healthy adults, with hypercholester…

• CLINICAL_TRIALS trial_result · 2025-06-11
  Clinical Trial Update: Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies. [Phase 3]

  A Phase 3 trial evaluating Obicetrapib in patients with familial hypercholesterolemia on maximally tolerated lipid-modifying therapy has com…

• CLINICAL_TRIALS trial_result · 2025-06-08
  Clinical Trial Update: How Cricket Powder Affects Gut Microbiome and Cholesterol Metabolism [NA]

  This update reports on a completed clinical trial evaluating the effects of cricket powder on gut microbiome and cholesterol metabolism in p…

• CLINICAL_TRIALS withdrawal · 2025-06-05
  Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Elevated Cholesterol

  A pilot clinical trial investigating the role of gut flora in elevated cholesterol has been withdrawn from the registry.

• EMA approval · 2025-06-03
  EMA Authorised: Cholestagel (colesevelam (as hydrochloride)) — CHEPLAPHARM Arzneimittel GmbH

  The EMA authorised Cholestagel (colesevelam as hydrochloride) for hypercholesterolemia, with CHEPLAPHARM Arzneimittel GmbH as the marketing …

• CLINICAL_TRIALS trial_result · 2025-05-28
  Clinical Trial Update: Evaluation of Green Tea for Improving Blood Lipid Profile [NA]

  A Taipei Medical University-backed clinical trial is evaluating whether green tea can improve blood lipid profiles in hypercholesterolemia; …

• CLINICAL_TRIALS trial_result · 2025-05-22
  Clinical Trial Update: Study of the Effects of Yerba Mate on Cardiometabolic Health [NA]

  A completed clinical trial evaluating the effects of Yerba Mate on cardiometabolic health, sponsored by Instituto de Ciencia y Tecnología de…

• CLINICAL_TRIALS trial_result · 2025-05-21
  Clinical Trial Update: Impact of Phytosterol-Rich Extract on Lipid Profile [NA]

  This clinical trial update describes an investigation of a phytosterol-rich extract and its effect on lipid profiles in individuals with ele…

• CLINICAL_TRIALS research · 2025-05-09
  Clinical Trial Update: Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry

  A prospective German registry completed that collects data on dyslipidemia treatment indications in patients at very high cardiovascular ris…

• CLINICAL_TRIALS trial_result · 2025-05-08
  Clinical Trial Update: A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease [Phase 1]

  Phase 1 trial update reporting completion of the study of VERVE-101 in patients with heterozygous familial hypercholesterolemia and cardiova…

• CLINICAL_TRIALS trial_result · 2025-05-01
  Clinical Trial Update: Evaluation of the Functionality of an Extract Rich in Phytosterols and Phytostanols on Parameters Related to the Lipid Profile of Individuals With Hypercholesterolemia, Mainly in the Levels of Total Cholesterol, LDL Cholesterol and Oxidized LDL [NA]

  A completed clinical trial evaluated the effect of a phytosterol and phytostanol-rich extract on lipid parameters (total cholesterol, LDL ch…

• CLINICAL_TRIALS trial_result · 2025-04-20
  Clinical Trial Update: Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol. [Phase 3]

  Phase 3 trial evaluating inclisiran as monotherapy in Chinese adults with elevated LDL-C and low-to-moderate ASCVD risk shows efficacy and s…