Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-13Clinical Trial Update: Examination of the Effects of Chromium Levels on Glucose Metabolism, Lipid Metabolism, Morbidity and Mortality Rates in Patients Followed in Intensive Care Unit
A completed clinical trial (NCT06334042) assessed how chromium levels influence glucose and lipid metabolism as well as morbidity and mortal…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Single Dose Oral Bioequivalence Study of Bempedoic Acid 180 mg Film Coated Tablet and Nilemdo® (Bempedoic Acid) 180 mg Film-coated Tablets in Healthy Adult Human Subjects Under Fasting Conditions. [Phase 1]
A Phase 1 bioequivalence study comparing a single-dose 180 mg bempedoic acid film-coated tablet to Nilemdo 180 mg film-coated tablets was co…
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FDA approval · 2025-04-10FDA Approved: ROSUVASTATIN CALCIUM — Supplemental Application (PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS)
The FDA approved a supplemental application for rosuvastatin calcium from Puracap Laboratories LLC dba Blu Pharmaceuticals, granting approva…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Peripheral Treg Cell Senescence & Serum Total Cholesterol Level
This completed clinical trial from Tianjin Medical University examined the relationship between peripheral T regulatory cell senescence and …
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: the Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects in Adult Subjects With Elevated LDL-C [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamic effects of a therapy aimed at lowering LDL-C in adults …
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study [NA]
The STAREE Heart Sub-study trial update reports ongoing research evaluating statin use to reduce cardiovascular events in elderly participan…
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: To Compare the Effect of Concomitant Administration of Probucol and Cilostazol With Probucol Single Treatment on the Atherosclerosis Related Markers (Including the Thickness of the Achilles Tendon) and Evaluate Safety (Based on Atorvastatin Treatment) in Severe Hypercholesterolemia Subject [Phase 4]
A Phase 4 clinical trial update comparing concurrent probucol and cilostazol versus probucol alone, assessing atherosclerosis-related marker…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Effect of LIMICOL®-NG on Plasma LDL-cholesterol Concentration in Subjects with Moderate Hypercholesterolemia [NA]
A clinical trial is evaluating the effect of LIMICOL®-NG on plasma LDL-cholesterol in adults with moderate hypercholesterolemia; the study i…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Non-interventional Study on the Monthly Administration of 300 mg AliRocumab (PRALUENT®) With the 2 ml SYDNEY Auto-injector
This entry reports the completion of a non-interventional study evaluating monthly 300 mg alirocumab (PRALUENT) administered using the SYDNE…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284 [Phase 1]
Phase 1 trial comparing pharmacokinetics and safety profiles of two investigational agents, AD-228B and AD-2284. The study is currently recr…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: A Study on Evaluating the Safety of HST101 in Healthy Chinese Participants [Phase 1]
Phase 1 safety study of HST101 in healthy Chinese participants, currently enrolling by invitation to assess safety in individuals with hyper…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: A Confirmatory Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia [Phase 3]
ETC-1002, a lipid-lowering agent, completed a confirmatory Phase 3 trial in patients with hyper-LDL cholesterolemia. Results from the comple…
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FDA approval · 2025-03-12FDA Approved: ROSUVASTATIN — Supplemental Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' supplemental application for rosuvastatin (generic rosuvastatin), authorizing its marketing in the Unit…
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CLINICAL_TRIALS withdrawal · 2025-03-06Clinical Trial Update: Impact of Cholesterol Level on Long-term Coronary Bypass Graft Patency
A clinical trial evaluating how cholesterol levels affect long-term patency of coronary artery bypass grafts has been withdrawn; the study i…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: PMMHRI-Pitavastatin Registry
Clinical trial registry update for the PMMHRI-Pitavastatin Registry, targeting hypercholesterolemia with recruitment ongoing.
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Clinical Trials of Effects of Time Restricted Eating on Health Parameters in Adults [NA]
This completed clinical trial evaluated the effects of time-restricted eating on multiple health parameters in adults. The study assessed ob…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: A Study of PCSK9 Inhibitor AK102 in Healthy Subjects [Phase 1]
Phase 1 trial evaluating the PCSK9 inhibitor AK102 in healthy subjects has completed.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Renal Impairment Study (MK-0616-020) [Phase 1]
Phase 1 renal impairment study of MK-0616 (Enlicitide Decanoate), an oral PCSK9 inhibitor, in hypercholesterolemia has completed with result…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Phase 2a Study to Assess CIVI 007 in Patients on a Background of Statin Therapy [Phase 2]
Phase 2a trial evaluating CIVI 007 in hypercholesterolemia patients on background statin therapy; results from the study have been completed…
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FDA label_change · 2025-02-12FDA Approved: EZALLOR SPRINKLE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for EZALLOR SPRINKLE (rosuvastatin) to support the sprinkle dosage-form labeling. This action expand…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Functional Cereal Products and Contribution to the Regulation of Metabolism and Obesity-induced Chronic Low-grade Inflammation. [NA]
A clinical trial update indicating Harokopio University is enrolling participants in a study of functional cereal products to regulate metab…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia [Phase 3]
A Phase 3 study evaluating the efficacy and safety of HST101 in Chinese patients with hypercholesterolemia and related dyslipidemias; the tr…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Evaluation of the Effects of Two Dietary Supplement Formulations on the Lipid Profile in Mild Hypercholesterolemia [NA]
A clinical trial is evaluating two dietary supplement formulations for their effect on lipid profiles in adults with mild hypercholesterolem…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Co-administration of AD-2281 and AD-2282 [Phase 3]
This document reports a Phase 3 clinical trial to evaluate the efficacy and safety of co-administration of AD-2281 and AD-2282 for Primary H…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Multicenter, Prospective, Non-interventional, Observational Study to Confirm the Long-term Efficacy and Safety of Rosuampin Tab. in Patients With Hypertension and Hypercholesterolemia
A multicenter, non-interventional observational study completed to assess the long-term efficacy and safety of Rosuampin Tablet in patients …