Hypercholesterolemia
📧 Sign up to get email alerts when something new happens for Hypercholesterolemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH) [Phase 3]
Phase 3 trial update for Enlicitide Decanoate (MK-0616), an oral PCSK9 inhibitor, in adults with heterozygous familial hypercholesterolemia,…
-
CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: A Long-term Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia [Phase 3]
Phase 3 long-term trial results for ETC-1002 (bempedoic acid) in adults with hypercholesterolemia were completed, with results posted in Feb…
-
CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: A Study to Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia [Phase 2]
A Phase 2 trial evaluating the safety and efficacy of SYH2053 in Chinese participants with non-familial hypercholesterolemia and mixed hyper…
-
CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study to Assess the Real-World Effectiveness of Inclisiran and PCSK9 mAbs in Chinese Hypercholesterolemia Adult Patients
A completed real-world study assessing the effectiveness of inclisiran and PCSK9 monoclonal antibodies in Chinese adults with hypercholester…
-
CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: A Study Of SHR-1918 In Participants With Hypercholesterolemia With Inadequate Lipid Control on Statins Plus PCSK9 Inhibitors [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial update for SHR-1918 in hypercholesterolemia patients not adequately controlled on statins plus PCSK9 inhibi…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: DNV001 Injection in Patients With Hypercholesterolemia [Phase 2]
Phase 2 trial of DNV001 Injection for primary hypercholesterolemia is currently not yet recruiting.
-
CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Improving Lipid Optimization Quality and Treatment Options in ASCVD [NA]
An ongoing, invitation-only clinical trial sponsored by Brigham and Women's Hospital focusing on improving lipid management for hypercholest…
-
CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Study on the Effect of the Intake of a Calcium-bicarbonate Water on Cholesterol Levels [NA]
A clinical trial is examining whether intake of calcium-bicarbonate water affects cholesterol levels in people with hypercholesterolemia; th…
-
CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Efficacy and Safety of Livalozet® in Hypercholesterolemic Patients With and Without Diabetes
This completed trial evaluated the efficacy and safety of Livalozet in adults with hypercholesterolemia, including participants with and wit…
-
CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Study Evaluating LDL-C Change and Adherence to Inclisiran Lipid-lowering Therapy in ASCVD
Novartis is conducting a clinical trial evaluating LDL-C changes and adherence to inclisiran in a population including primary hypercholeste…
-
CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy
A multicenter study in Italy is evaluating adherence, persistence and efficacy of bempedoic acid for hypercholesterolemia and is currently r…
-
CLINICAL_TRIALS other · 2026-01-22Clinical Trial Update: Evaluation of Adherence, Persistence and Efficacy of Treatment With PCSK9 Inhibitors in Italy
This clinical trial update notes that a study evaluating adherence, persistence and efficacy of PCSK9 inhibitors for hypercholesterolemia in…
-
CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Inclisiran in Italy
A multicenter study in Italy evaluating adherence, persistence and efficacy of Inclisiran in patients with hypercholesterolemia.
-
CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease. [Phase 4]
Phase 4 trial comparing LDL-cholesterol lowering with Inclisiran versus Bempedoic acid in patients with atherosclerotic cardiovascular disea…
-
CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy
A Johns Hopkins University-sponsored study is evaluating the impact of ketogenic diets on cardiovascular health in adults with epilepsy. It …
-
FDA label_change · 2026-01-09FDA Approved: NEXLETOL — Supplemental Application (Esperion Therapeutics, Inc.)
The FDA approved a supplemental application for Nexletol (bempedoic acid) from Esperion Therapeutics, Inc., expanding the drug's labeling.
-
CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C) [Phase 3]
Phase 3 clinical trial update evaluating the efficacy and safety of Inclisiran in Asian participants with atherosclerotic cardiovascular dis…
-
CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: LATAM LOWERS LDL-C [Phase 4]
Novartis is conducting a Phase 4 trial in Latin America to lower LDL-C in individuals with hypercholesterolemia; the study is currently recr…
-
CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: An Efficacy and Safety Study of Akkermansia Muciniphila AKM Lab-01 in Hypercholesterolaemia [NA]
This clinical trial update reports that a study evaluating the efficacy and safety of Akkermansia muciniphila AKM Lab-01 for hypercholestero…
-
CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis [Phase 2]
A Phase 2 trial comparing early statin-ezetimibe combination therapy to statin monotherapy in patients with stroke due to atherosclerosis is…
-
CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists [Phase 2]
Phase 2 trial evaluating RDX-002's effect on postprandial triglycerides in patients discontinuing GLP-1 agonists; study completed.
-
CLINICAL_TRIALS other · 2025-12-22Clinical Trial Update: Leqvio rPMS (Regulatory Post-Marketing Surveillance in Korea)
This is a regulatory post-marketing surveillance study in Korea for Leqvio (inclisiran) in patients with primary hypercholesterolemia or mix…
-
CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: A Study of SAL003 in Participants With Hypercholesterolemia and Mixed Dyslipidemia [Phase 3]
Phase 3 clinical trial SAL003 in hypercholesterolemia and mixed dyslipidemia has completed enrollment and status is updated.
-
CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Effect of Two Food Supplements on Lipid Profile in Patients With Mild Hypercholesterolemia [NA]
This clinical trial entry describes a study evaluating the effect of two food supplements on lipid profiles in patients with mild hyperchole…
-
CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Statin Reminders for Improving Prescribing in Primary Care [NA]
A completed clinical trial evaluating the impact of statin reminders on prescribing in primary care for hypercholesterolemia.