Hypercholesterolemia
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
A clinical trial evaluating bempedoic acid in combination with ezetimibe and either rosuvastatin or atorvastatin in people with primary hype…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Causes and Natural History of Dyslipidemias
This clinical trial update discusses the causes and natural history of dyslipidemias, including hypercholesterolemia and atherosclerosis, sp…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia
This clinical trial evaluates bempedoic acid alone or in a fixed-dose single-pill combination with ezetimibe for primary hypercholesterolemi…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Enlicitide (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018/CORALreef AddOn) [Phase 3]
A Phase 3 study evaluating the efficacy and safety of Enlicitide (MK-0616) versus ezetimibe, bempedoic acid, or their combination in adults …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias [Phase 1]
The trial is a Phase 1 safety and tolerability study of CTX310 in participants with refractory dyslipidemias. It is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: A Prospective, Open, Observational Study to Confirm the Lipid-lowering Effect, Changes in Glucose Metabolism, and Safety After 6 Months of Administration of Atostazet to Hypercholesterolemic Patients 65 Years of Age or Older
A completed prospective observational trial evaluating the lipid-lowering effect, changes in glucose metabolism, and safety of Atostazet in …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Mechanism of Ketogenic Diet-Induced Hypercholesterolemia [NA]
This clinical trial update from Washington University School of Medicine describes a study on the mechanism by which a ketogenic diet may in…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Real World Adherence of PCSK9 Targeted Therapy
Novartis sponsors a real-world study to evaluate adherence to a PCSK9-targeted therapy in patients with dyslipidemia and hypercholesterolemi…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia
Clinical trial update on treatment with bempedoic acid and its fixed-dose combination with ezetimibe for primary hypercholesterolemia and mi…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Red Yeast Rice for Primary Prevention of Hypercholesterolemia
A clinical trial evaluating red yeast rice for primary prevention of hypercholesterolemia has completed, sponsored by Chang Gung Memorial Ho…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events [Phase 3]
Phase 3 study evaluating a combination of bempedoic acid, ezetimibe, and a high-intensity statin in patients without cardiovascular events; …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Elevated Lipoprotein(a) in Hospital Staff
The update describes a clinical trial studying elevated lipoprotein(a) in hospital staff with hypercholesterolemia and related cardiovascula…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of weekly alirocumab in adults with hypercholesterolemia; the study is currently…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Electronic Letters to Improve Patient Activation in IHD: The NUDGE-IHD Trial [NA]
A clinical trial update for the NUDGE-IHD study investigating electronic letters to improve patient activation in ischemic heart disease; th…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of DW5421A/DW5421B Compared to Monotherapy of DW5421A [Phase 3]
A Phase 3 trial evaluated the combination DW5421A/DW5421B versus DW5421A monotherapy for primary hypercholesterolemia and mixed dyslipidemia…
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FDA approval · 2026-03-05FDA Approved: CHOLESTYRAMINE — Original Application (Micro Labs Limited)
FDA approves Micro Labs Limited's original application for CHOLESTYRAMINE, a generic bile acid sequestrant used to lower cholesterol in pati…
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EMA approval · 2026-03-04EMA Authorised: Leqvio (inclisiran) — Novartis Europharm Limited
The European Medicines Agency authorised Leqvio (inclisiran) from Novartis Europharm Limited for hypercholesterolemia and dyslipidemias, wit…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: QLC7401 in the Treatment of Primary Hypercholesterolemia or Mixed Hyperlipidemia With Elevated Low Density Lipoprotein Cholesterol (LDL-C) [Phase 3]
A Phase 3 clinical trial evaluating QLC7401 for primary hypercholesterolemia or mixed hyperlipidemia with elevated LDL-C; the study is not y…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Efficacy and Safety of Pitavastatin/Ezetimibe After Switching From Statin Monotherapy to Pitavastatin/Ezetimibe in Patients With Hypercholesterolemia
A completed clinical trial evaluating the efficacy and safety of switching to Pitavastatin/Ezetimibe in patients with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Long-term Comparison of Pitavastatin/Ezetimibe and Pitavastatin in Patients With Hypercholesterolemia and Elevated Triglycerides [Phase 4]
Phase 4 trial comparing long-term outcomes of pitavastatin/ezetimibe versus pitavastatin alone in patients with hypercholesterolemia and ele…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: QLC7401 Monotherapy in Non-familial Hypercholesterolemia or Mixed Dyslipidemia [Phase 3]
A Phase 3 clinical trial update for QLC7401 monotherapy in primary hypercholesterolemia or mixed dyslipidemia, sponsored by Qilu Pharmaceuti…
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EMA approval · 2026-02-27EMA Authorised: Nilemdo (bempedoic acid) — Daiichi Sankyo Europe GmbH
The European Medicines Agency authorised Nilemdo (bempedoic acid) for hypercholesterolemia and related dyslipidemias. The marketing authoris…
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EMA approval · 2026-02-27EMA Authorised: Nustendi (bempedoic acid;ezetimibe) — Daiichi Sankyo Europe GmbH
The EMA has authorised Nustendi, a fixed-dose combination of bempedoic acid and ezetimibe, for hypercholesterolemia and related dyslipidemia…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial [Phase 2]
A Phase 2 clinical trial titled 'Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders' is currently recruiting. The study i…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study of STX-1150 in Participants With Elevated Low-Density Lipoprotein Cholesterol (LDL-C) [Phase 1]
This is a Phase 1 clinical trial update for STX-1150 in participants with elevated LDL cholesterol/high cholesterol, currently not recruitin…