Huntington Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-01-29Clinical Trial Update: Study Exploring Safety, Pharmacokinetic and Pharmacodynamic of BN82451 in Male Huntington's Disease Patients [Phase 2]
A Phase 2 trial evaluating the safety, pharmacokinetics, and pharmacodynamics of BN82451 in males with Huntington's disease was terminated; …
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Neuroleptic and Huntington Disease Comparison of : Olanzapine, la Tetrabenazine and Tiapride [Phase 3]
A Phase 3 clinical trial comparing olanzapine, tetrabenazine, and tiapride for Huntington disease has completed.
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease [Phase 2]
Phase 2 trial evaluating safety, tolerability, and brain function of two doses of PF-0254920 in early Huntington's disease completed with re…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's Disease [Phase 2]
A randomized, placebo-controlled Phase 2 trial evaluating the efficacy and safety of PF-02545920 in Huntington's disease was completed, with…
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's Disease
A completed clinical trial evaluated the impact of Xenazine (tetrabenazine) on gait and functional activity in individuals with Huntington's…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: MIG-HD: Multicentric Intracerebral Grafting in Huntington's Disease [Phase 2]
This clinical trial update reports the completion of a Phase 2 multicentric intracerebral grafting study for Huntington's disease.
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL) [Phase 2]
Phase 2 trial update for Coenzyme Q10 (ubiquinone) in PRE-manifest Huntington's Disease as a precursor to preventive trials; completed with …
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CLINICAL_TRIALS trial_result · 2017-08-11Clinical Trial Update: First Time Use of SD-809 in Huntington Disease [Phase 3]
Phase 3 trial update on the first use of SD-809 (deutetrabenazine) for Huntington disease–related chorea.
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CLINICAL_TRIALS trial_result · 2017-08-08Clinical Trial Update: FuRST 2.0 Cognitive Pre-Testing
The FuRST 2.0 cognitive pre-testing trial for Huntington's disease has completed.
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Evaluation of [123I]MNI-420 and SPECT as a Marker of the Adenosine A2a Receptor in PD, HD and Healthy Subjects. [Phase 1]
Phase 1 study evaluating [123I]MNI-420 with SPECT as a marker of the adenosine A2a receptor in Parkinson disease, Huntington disease, and he…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions [Phase 1]
Phase 1 PET imaging study of an mGluR5 tracer across several neuropsychiatric conditions has been completed.
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Study of Motor Slowing in Parkinson's Disease by a Computerized Mental Chronometry Paradigm
This completed clinical trial investigated motor slowing in Parkinson's disease using a computerized mental chronometry paradigm. Huntington…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease [Phase 3]
A Phase 3 clinical trial evaluating the safety and efficacy of dimebon (latrepirdine) in Huntington disease has completed.
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease [Phase 3]
This update reports the termination of an extension of the HORIZON trial evaluating the safety of Dimebon (latrepirdine) in Huntington's dis…
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CLINICAL_TRIALS trial_result · 2016-10-10Clinical Trial Update: Working Memory Training in Huntington's Disease [NA]
This clinical trial update indicates that the study evaluating working memory training for Huntington's disease has completed.
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Treadmill Walking in Individuals With Dementia With Lewy Bodies and Huntington's Disease [NA]
This clinical trial update indicates that the treadmill walking study involving individuals with Huntington's disease and dementia with Lewy…
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 "After Multiple Oral Doses" in Healthy Volunteers [Phase 1]
Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of PBF-999 after multiple oral doses in healthy volunteers; the tria…
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: Caregiver Burden in Huntington's Disease [NA]
This clinical trial update notes the completed status of a study evaluating caregiver burden in Huntington's disease patients, conducted by …
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Effect of PBT2 in Patients With Early to Mid Stage Huntington Disease [Phase 2]
Phase 2 trial of PBT2 in patients with early to mid-stage Huntington disease has been completed, with results posted.
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: [PETDE10] Imaging of PDE10A Enzyme Levels in Huntington's Disease Gene Expansion Carriers and Healthy Controls With PET. [EARLY_Phase 1]
This record reports the completion of a Phase 1 PET imaging trial evaluating PDE10A enzyme levels in Huntington's disease gene expansion car…
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Bioavailability of Ubiquinol in Huntington Disease [Phase 1]
Phase 1 study evaluated the bioavailability of ubiquinol in individuals with Huntington's disease and is completed.
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CLINICAL_TRIALS trial_result · 2016-03-30Clinical Trial Update: Coenzyme Q10 in Huntington's Disease (HD) [Phase 3]
A Phase 3 trial of Coenzyme Q10 for Huntington's disease was terminated, and the results have been posted.
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Proof of Concept of an Anaplerotic Study Using Brain Phosphorus Magnetic Resonance Spectroscopy in Huntington Disease [Phase 2]
Phase 2 proof-of-concept study in Huntington's disease evaluating an anaplerotic approach using brain phosphorus MR spectroscopy; results we…
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E) [Phase 3]
The Phase 3 CREST-E trial evaluating creatine for Huntington's disease has been terminated.
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Study To Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-999 in Healthy Young Male Volunteers [Phase 1]
Phase 1 study assessing safety and tolerability of single ascending oral doses of PBF-999 in healthy young male volunteers; Huntington's dis…