Huntington Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-09-02Clinical Trial Update: A Pilot Study Assessing Impulsivity in Patients With Huntington's Disease on Xenazine (Tetrabenazine) [Phase 4]
A Phase 4 pilot trial evaluating impulsivity in Huntington's disease patients treated with Xenazine (tetrabenazine).
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi [Phase 2]
Phase 2 study in Huntington's disease evaluating safety, tolerability, pharmacokinetics, and efficacy of Pepi has completed.
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CLINICAL_TRIALS trial_result · 2022-04-25Clinical Trial Update: Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease [Phase 1, Phase 2]
Phase 1/2 trial of WVE-120102 in Huntington's disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: Within Subject Crossover Study of Cognitive Effects of Neflamapimod in Early-Stage Huntington Disease [Phase 2]
Phase 2 within-subject crossover trial of neflamapimod in early-stage Huntington disease; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-02-10Clinical Trial Update: Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease [Phase 1, Phase 2]
A combined Phase 1/2 trial assessing safety and tolerability of WVE-120101 in Huntington's disease was terminated with results posted in 202…
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Open-label Extension Study of Pridopidine (ACR16) in the Symptomatic Treatment of Huntington Disease [Phase 2]
Open-label extension study results for pridopidine (ACR16) in symptomatic treatment of Huntington disease (Phase 2) completed; results poste…
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease [Phase 1, Phase 2]
Open-label extension study evaluating safety and tolerability of WVE-120102 in Huntington's disease; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease [Phase 1, Phase 2]
Open-label extension study evaluating safety and tolerability of WVE-120101 in Huntington's disease was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-11-16Clinical Trial Update: A Study to Evaluate Sigma-1 and Dopamine-2 Receptor Occupancy by Pridopidine in the Human Brain of Healthy Volunteers and in Patients With Huntington's Disease [Phase 1]
Phase 1 study evaluating sigma-1 and D2 receptor occupancy by pridopidine in healthy volunteers and Huntington's disease patients; completed…
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CLINICAL_TRIALS trial_result · 2021-09-17Clinical Trial Update: A Study Evaluating if Pridopidine is Safe, Efficacious, and Tolerable in Patients With Huntington's Disease [Phase 2]
Phase 2 trial evaluating pridopidine in Huntington's disease; the study is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease [NA]
A completed clinical trial assessing the effects of video game–based exercise on dynamic balance and gait in individuals with Huntington's d…
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CLINICAL_TRIALS trial_result · 2021-07-19Clinical Trial Update: A Phase 2, to Evaluating the Safety and Efficacy of Pridopidine Vs Placebo for Symptomatic Treatment in Patients With Huntington's Disease [Phase 2]
Phase 2 trial evaluating pridopidine versus placebo for symptomatic treatment in Huntington's disease completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139) [Phase 2]
A Phase 2 trial evaluating safety, tolerability, PK, and PD of RO7234292 (ISIS 443139) in Huntington's disease patients who participated in …
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CLINICAL_TRIALS trial_result · 2021-01-05Clinical Trial Update: Study of Memantine to Treat Huntington's Disease [Phase 4]
A Phase 4 trial evaluating memantine for Huntington's disease has completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-04-20Clinical Trial Update: Electronic-health Application To Measure Outcomes REmotely Clinical Trial [NA]
A completed clinical trial using an electronic health application to measure outcomes remotely in neurodegenerative disease contexts, with r…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: A Trial of Memantine as Symptomatic Treatment for Early Huntington Disease [Phase 2]
A Phase 2 clinical trial evaluating memantine as symptomatic treatment for early Huntington disease has been completed.
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CLINICAL_TRIALS trial_result · 2019-09-16Clinical Trial Update: Efficacy and Safety of SOM3355 in Huntington's Disease Chorea [Phase 2]
Phase 2 trial update reporting efficacy and safety of SOM3355 in Huntington's disease chorea.
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CLINICAL_TRIALS trial_result · 2019-06-19Clinical Trial Update: A Clinical Study in Participants With Huntington's Disease (HD) to Assess Efficacy and Safety of Three Oral Doses of Laquinimod [Phase 2]
Phase 2 trial evaluating three oral doses of laquinimod in Huntington's disease has been completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-05-31Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's Disease [Phase 1, Phase 2]
A Phase 1/2 study assessing safety, tolerability, pharmacokinetics, and pharmacodynamics of ISIS 443139 in individuals with early manifest H…
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CLINICAL_TRIALS trial_result · 2019-05-30Clinical Trial Update: Feasibility and Acceptability of Implementing a Clinic-based Physical Activity Coaching Intervention in People With Premanifest and Early Stage HD [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating the feasibility and acceptability of a clinic-based physical activity coaching intervention …
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Alternatives for Reducing Chorea in Huntington Disease [Phase 3]
Phase 3 trial evaluating alternatives for reducing chorea in Huntington disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Accelerated Diffusion MRI for Diagnosis of Hungtington Disease
The trial update reports completion of a study evaluating accelerated diffusion MRI as a diagnostic method for Huntington disease.
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: Exercise Effects in Huntington's Disease [NA]
This update reports a completed trial evaluating the effects of exercise on Huntington's disease.
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021 [Phase 2]
Pfizer conducted an open-label extension to evaluate the long-term safety, tolerability, and efficacy of Pf-02545920 in Huntington's disease…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients
Completed clinical trial evaluating the relationship between morphine consumption and pain-related biomarkers in hepatic surgical patients.