Huntington Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Preparing for Prevention of Huntington's Disease (PREVENT-HD)
The PREVENT-HD trial for Huntington's disease prevention, sponsored by the University of Wisconsin–Madison, has completed.
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Handgrip and Respiratory Dysfunction in HD Patients.
This clinical trial update indicates that the study evaluating handgrip strength and respiratory dysfunction in Huntington disease patients …
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD [Phase 3]
The PROOF-HD Phase 3 trial evaluating pridopidine's impact on function in Huntington disease has completed, and the results have been posted…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's Disease [Phase 1, Phase 2]
Clinical trial update describes the safety and efficacy evaluation of AMT-130 in European adults with early manifest Huntington disease acro…
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of MBF-015 in Huntington's Disease Patients [Phase 2]
A Phase 2 clinical trial evaluating MBF-015 for Huntington disease has completed, reporting on safety, pharmacokinetics, and pharmacodynamic…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Efficacy of Deutetrabenazine to Control Symptoms of Dysphagia Associated with HD [Phase 1]
Phase 1 trial of deutetrabenazine for dysphagia in Huntington disease was terminated; no conclusive efficacy results are reported.
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest Stage I or Stage II Huntington's Disease [Phase 1]
Roche completed a Phase 1 biomarker study in early manifest Huntington's disease to measure cerebrospinal fluid mutant huntingtin protein; r…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Measurement and Modification of Threat Interpretation Bias in Neurodegenerative Movement Disorders (Aims 2 & 3) [NA]
Completed clinical trial evaluating measurement and modification of threat interpretation bias in Huntington's disease and Parkinson's disea…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects [Phase 1]
Phase 1 study assessing safety, tolerability and pharmacokinetics of escalating doses of LPM3770164 in healthy subjects, with potential rele…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Effect of Food on the Pharmacokinetics of LPM3770164 Sustained-release Tablets [Phase 1]
A Phase 1 clinical trial evaluating the effect of food on the pharmacokinetics of LPM3770164 sustained-release tablets. The study is complet…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Clinical Study to Monitor Plasma Levels of 24OHC in Subject with HD
The clinical study monitoring plasma levels of 24-hydroxycholesterol in a subject with Huntington's disease has completed.
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's Disease [Phase 2]
A Phase 2 dose-ranging study with an open-label extension evaluated the safety of oral branaplam (LMI070) in individuals with early manifest…
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's Disease [Phase 1]
Phase 1 study evaluating pharmacokinetics, pharmacodynamics, and safety/tolerability of intrathecal RO7234292 (RG6042) in Huntington's disea…
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CLINICAL_TRIALS trial_result · 2024-07-15Clinical Trial Update: A Comparative Phase 2 Study Assessing the Efficacy of Triheptanoin, an Anaplerotic Therapy in Huntington's Disease [Phase 2]
This completed Phase 2 trial evaluated Triheptanoin as anaplerotic therapy for Huntington disease.
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease [Phase 3]
Phase 3 study evaluating dextromethorphan/quinidine for irritability in Huntington's disease has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's Disease [Phase 3]
Phase 3 trial evaluating intrathecal RO7234292 (RG6042) for Huntington's disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: Efficacy and Safety of NestaCell® in Huntington's Disease [Phase 3]
Phase 3 trial update on NestaCell® for Huntington's disease, focusing on efficacy and safety.
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington Disease [Phase 3]
Phase 3 trial update on valbenazine for chorea in Huntington disease, reporting efficacy, safety, and tolerability results.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Safety and Efficacy of Fenofibrate as a Treatment for Huntington's Disease [Phase 2]
Phase 2 trial update on fenofibrate for Huntington's disease, reporting safety and efficacy results.
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored Studies [Phase 3]
Open-label extension study assessing long-term safety and tolerability of RO7234292 (RG6042) in Huntington's disease participants from prior…
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: A Study of Pridopidine (ACR16) for the Treatment of Participants With Huntington's Disease [Phase 2]
A Phase 2 clinical trial of pridopidine (ACR16) for Huntington's disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-29Clinical Trial Update: A Study of Treatment With Pridopidine (ACR16) in Participants With Huntington's Disease [Phase 3]
Phase 3 clinical trial update for pridopidine (ACR16) in Huntington's Disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-07-20Clinical Trial Update: Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease [Phase 2]
Phase 2 trial update on SRX246 assessing tolerability, safety, and activity in irritable mood associated with Huntington's disease; study co…
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: An Open Label Study of ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease [Phase 2]
Phase 2 open-label study of ANX005 in subjects with or at risk for Huntington's disease has completed.
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Clinical Extension Study for Safety and Efficacy Evaluation of Cellavita-HD Administration in Huntington's Patients. [Phase 2, Phase 3]
A clinical extension study is being conducted to evaluate safety and efficacy of Cellavita-HD in Huntington's disease patients across Phase …