Hospital-acquired Pneumonia
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired Pneumonia [NA]
This clinical trial update reports on evaluating a DNA-based strategy to tailor antibiotic therapy for patients with hospital-acquired pneum…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Identifying Risk Factors for Gram-negative Resistance for HAP/VAP in the Intensive Care Unit
A completed clinical trial update examining risk factors for Gram-negative resistance in ventilator-associated pneumonia and hospital-acquir…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Steriwave ICU Pilot Study [NA]
Clinical trial update indicating that Fraser Health's Steriwave ICU Pilot Study has completed; the study targeted ventilator-associated pneu…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants [Phase 2]
A Phase 2 study assessing safety, tolerability, and pharmacokinetics of cefiderocol in hospitalized pediatric participants has completed wit…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL [Phase 3]
Phase 3 trial evaluating acyclovir in ventilated patients with pneumonia and HSV-1 detected in BAL is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia. [NA]
A completed clinical trial evaluating a strategy that combines rapid diagnostic testing with antimicrobial stewardship to improve antibiotic…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants With Bacterial Pneumonia (XNW4107-302, REITAB-2) [Phase 3]
Phase 3 trial comparing Imipenem/Cilastatin-XNW4107 with Imipenem/Cilastatin/Relebactam in hospital-acquired and ventilator-associated pneum…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036) [Phase 1]
Phase 1 safety and pharmacokinetics study of ceftolozane/tazobactam in pediatric participants with hospital-acquired pneumonia (MK-7625A-036…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Real-World Study of Ceftazidime Avibactam in China
Real-world study of ceftazidime-avibactam in China was terminated, with results posted, evaluating its use for hospital-acquired pneumonia, …
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults [Phase 4]
Phase 4 trial results evaluate the efficacy and safety of ceftazidime-avibactam (CAZ-AVI) for carbapenem-resistant Gram-negative infections …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Efficacy and Safety of Ceftazidime-Avibactam (CAZ-AVI) in Chinese Participants With HAP (Including VAP) [Phase 4]
Phase 4 study assessing the efficacy and safety of Ceftazidime-Avibactam in Chinese patients with hospital-acquired pneumonia, including ven…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia [Phase 2]
A Phase 2 trial evaluating presepsin as a biomarker to guide immunotherapy in pneumonia has completed, including community-acquired pneumoni…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria. [Phase 3]
Phase 3 study evaluating aztreonam-avibactam ± metronidazole versus meropenem ± colistin for serious Gram-negative infections, including com…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics [Phase 4]
Phase 4 clinical trial evaluating rapid diagnostic-guided use of ceftazidime-avibactam for bloodstream infections and ventilator-associated …
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: Efficacy of Intravenous Amboxol Hydrochloride as an Adjunct Therapy for Severe Pneumonia in Critically Ill Patients [Phase 4]
Phase 4 trial updates the efficacy of intravenous Amboxol hydrochloride as an adjunct therapy for severe pneumonia in critically ill patient…
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CLINICAL_TRIALS trial_result · 2023-06-28Clinical Trial Update: Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016) [Phase 3]
Phase 3 trial MK-7655A-016 comparing Imipenem/Cilastatin/Relebactam to Piperacillin/Tazobactam in hospital-acquired and ventilator-associate…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. [Phase 2, Phase 3]
Clinical trial updates for baricitinib in hospital-acquired pneumonia in critically ill patients with a proinflammatory phenotype across Pha…
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CLINICAL_TRIALS trial_result · 2022-09-09Clinical Trial Update: Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial Pneumonia [Phase 1]
Phase 1 single-dose pharmacokinetic study of ceftazidime-avibactam in hospitalized children receiving systemic antibiotics for suspected or …
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CLINICAL_TRIALS trial_result · 2022-02-16Clinical Trial Update: Human Recombinant Interferon Gamma-1b for the Prevention of Hospital-acquired Pneumonia in Critically Ill Patients: a Double-blind, International, Phase 2, Randomized, Placebo-controlled Trial - the PREV-HAP Study [Phase 2]
A Phase 2 randomized trial evaluating human recombinant interferon gamma-1b for preventing hospital-acquired pneumonia in critically ill pat…
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: Effect of Angulus on Patient-elevation Compliance [NA]
Clinical trial completed investigating Angulus and its impact on patient-elevation compliance in ventilated patients; results posted in 2021…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens [Phase 3]
Phase 3 trial evaluating Cefiderocol (S-649266) versus best available therapy for severe infections due to carbapenem-resistant Gram-negativ…
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CLINICAL_TRIALS trial_result · 2020-11-13Clinical Trial Update: Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens [Phase 3]
Phase 3 clinical trial of Cefiderocol for healthcare-associated pneumonia and hospital-acquired pneumonia has completed with results posted …
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CLINICAL_TRIALS trial_result · 2020-09-11Clinical Trial Update: Ceftobiprole in the Treatment of Pediatric Patients With Pneumonia [Phase 3]
Phase 3 pediatric trial update for ceftobiprole in community-acquired and hospital-acquired pneumonia; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae
Completed clinical trial investigating cases of serious infections due to carbapenem-resistant Enterobacteriaceae across multiple infection …
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Mechanical Ventilation Parameters in HAP Patients
A clinical trial assessing mechanical ventilation parameters in patients with hospital-acquired pneumonia has completed.