Hospital-acquired Pneumonia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant Enterobacterales [Phase 3]
A Phase 3 clinical trial update reporting completion of studies evaluating Cefepime/Nacubactam and Aztreonam/Nacubactam vs best available th…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Study on the Safety and Efficacy of Polymyxin E2 Methanesulfonate for Injection in the Treatment of Hospital-Acquired Bacterial Pneumonia/Ventilator-Associated Bacterial Pneumonia Caused by Carbapenem-Resistant Gram-Negative Bacteria [Phase 2]
A Phase 2 clinical study is assessing the safety and efficacy of Polymyxin E2 methanesulfonate for injection for treating hospital-acquired …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Real-World Effectiveness of Aztreonam-Avibactam Against MBL-Producing CRE
This clinical trial update reports ongoing real-world evaluation of the aztreonam-avibactam combination against metallo-beta-lactamase-produ…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Nosocomial Pneumonia After Coronary Artery Bypass Grafting
A clinical trial entry indicating the study is recruiting to investigate hospital-acquired pneumonia after coronary artery bypass grafting. …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Meropenem and Pralurbactam in HABP/VABP [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Meropenem plus Pralurbactam for hospital-acquired pneumonia and ventilator-associated pn…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex [Phase 3]
Phase 3 trial evaluating BV100 with low-dose Polymyxin B versus Colistin with high-dose ampicillin/sulbactam for hospital-acquired and venti…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical Ventilation [NA]
This clinical trial evaluates using bacterial DNA detection to guide antibiotic choices in immunocompromised patients with hospital-acquired…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Definition of Sub-phenotypes of Pneumonia Based on the Respiratory Microbiome Composition to Predict Microbial and Clinical Treatment Failures
This clinical trial seeks to define pneumonia sub-phenotypes based on the respiratory microbiome to predict microbial and clinical treatment…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Feasibility Study of Contemporary Diagnostics for Patients With Suspected Hospital-Acquired Pneumonia. [NA]
This document reports a completed feasibility study evaluating contemporary diagnostic approaches for patients with suspected hospital-acqui…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea
Pfizer is conducting a post-market study in Korea to gather information about Zavicefta (ceftazidime-avibactam) after it was released, cover…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: HAP/VAP Diagnosis in Critically Ill Septic Patients Using a Multiplex PCR Array [NA]
This entry notes that the clinical trial evaluating a multiplex PCR array for diagnosing hospital-acquired pneumonia and ventilator-associat…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype [Phase 3]
Phase 3 trial evaluating dexamethasone for treating severe hospital-acquired pneumonia in critically ill patients with a proinflammatory phe…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Pneumonia Pathogens' Virulence Factors, Patient Inflammatory Markers, and Their Associations With Outcomes
An ongoing clinical trial update explores how virulence factors of pneumonia pathogens and patient inflammatory markers relate to outcomes. …
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Optimising TREATment for Severe Gram-Negative Bacterial Infections [Phase 4]
Phase 4 study focused on optimizing treatment for severe gram-negative infections; the trial is currently recruiting. It encompasses bloodst…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Mechanical Insufflation-exsufflation and Hypertonic Saline in Nosocomial Bacterial Respiratory Tract Infection [NA]
A clinical trial in Madrid is evaluating mechanical insufflation-exsufflation and hypertonic saline for nosocomial bacterial respiratory tra…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Clinical Impact of a Multiplex Rapid Diagnostic Pneumonia Panel Testing in Critically-ill Patients With Severe Hospital-acquired Pneumonia, Ventilator-associated Pneumonia and Community-acquired Pneumonia With High Risk of Multidrug Resistant Pathogen [NA]
This clinical trial update evaluates the impact of a multiplex rapid diagnostic pneumonia panel in critically ill patients with severe hospi…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Long-term Alterations of Host-microbiome Interactions and Cardiovascular and Respiratory Diseases Progression After Pneumonia [NA]
A recruiting clinical trial studying long-term changes in host-microbiome interactions and the progression of cardiovascular and respiratory…
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CLINICAL_TRIALS research · 2020-11-13Clinical Trial Update: The Applicability of Different Scoring Systems and Use of Steroids in the Treatment of Hospital Acquired Pneumonia [Phase 4]
A Phase 4 trial update exploring scoring systems and steroid use in hospital-acquired pneumonia.
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CLINICAL_TRIALS research · 2017-10-06Clinical Trial Update: Characteristics of Lower Respiratory Tract Escherichia Coli Isolates in Mechanically Ventilated Intensive Care Patients
A completed clinical trial update describing characteristics of lower respiratory tract Escherichia coli isolates from mechanically ventilat…
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: Optimizing Dosing Regimen of Piperacillin/Tazobactam for Nosocomial Pneumonia [Phase 2, Phase 3]
Clinical trial update exploring how to optimize dosing of piperacillin/tazobactam for hospital-acquired pneumonia in Phase 2 and Phase 3 tri…
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CLINICAL_TRIALS research · 2015-11-25Clinical Trial Update: Epidemiology of Hospital Acquired Pneumonia
This clinical trial update reports on the epidemiology of hospital-acquired pneumonia, with a focus on bacterial respiratory infections.
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CLINICAL_TRIALS research · 2014-12-03Clinical Trial Update: Early Mobility Bundle to Prevent Hospital Acquired Pneumonia (HAP) in Medical Inpatients [NA]
A University of Birmingham trial evaluated an Early Mobility Bundle to prevent hospital-acquired pneumonia in medical inpatients. The study …
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CLINICAL_TRIALS research · 2014-07-29Clinical Trial Update: The Impact of Simultaneous Presence of Viral and Bacterial Pathogens on Therapy and Course of Severe Pneumonia
This clinical trial update investigates how simultaneous viral and bacterial pathogens influence therapy and outcomes in severe pneumonia.
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CLINICAL_TRIALS research · 2013-07-22Clinical Trial Update: Clinician Ability to Predict the Presence of Nosocomial Pneumonia Based on Bronchoscopic Findings
A completed clinical trial assessing whether clinicians can predict the presence of hospital-acquired pneumonia from bronchoscopic findings.
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CLINICAL_TRIALS research · 2011-01-20Clinical Trial Update: An Open-label, Randomized, and Comparative Study to Evaluate the Efficacy and Safety of Cefoperazone/Sulbactam in Comparison to Cefepime for the Treatment of Hospital-acquired Pneumonia and Healthcare-associated Pneumonia
An open-label randomized trial compares cefoperazone/sulbactam to cefepime for the treatment of hospital-acquired pneumonia and healthcare-a…