HIV Infection
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities [NA]
Trial to evaluate a seek-test-treat intervention aimed at reducing disparities in Chlamydia trachomatis infection and related STIs; the stud…
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FDA approval · 2024-05-23FDA Approved: NEVIRAPINE — Supplemental Application (Micro Labs Limited)
FDA approved a supplemental application for nevirapine from Micro Labs Limited, enabling the availability of a generic nevirapine product fo…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Assisted Notification of Partners of Men Having Sex With Men Discovering Their Seropositivity [NA]
This clinical trial update outlines an assisted notification approach for partners of men who have sex with men after discovering HIV seropo…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Preventive Therapy for Tuberculosis in HIV Infected Persons [Phase 3]
This Clinical Trial Update reports the completion of a Phase 3 trial evaluating preventive therapy for tuberculosis in HIV-infected individu…
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CLINICAL_TRIALS research · 2024-05-22Clinical Trial Update: Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique [NA]
A Mozambique clinical trial is evaluating the effectiveness of TA versus LEEP for cervical cancer risk reduction in women living with HIV; r…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: CCR5-modified CD4+ T Cells for HIV Infection [Phase 1, Phase 2]
This clinical trial update reports completed Phase 1 and Phase 2 studies evaluating CCR5-modified CD4+ T cells for HIV infection.
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: The OPENS Trial: Offering Women PrEP (Aim 1) [NA]
Clinical trial update for the OPENS trial indicates completion and posting of results evaluating offering pre-exposure prophylaxis to women.
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: A Pilot Peer Mentor Intervention That Trains Black Men Who Have Sex With Men (BMSM) to Use and Promote Uptake of HIV/STI Self-Testing to Peers and Sex Partners: STAR Study (Self-Testing at Your Residence) [NA]
Pilot peer mentor intervention to train Black men who have sex with men to use and promote uptake of HIV/STI self-testing. The trial has com…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Project MIX: Behavioral Intervention to Reduce Risk Among Substance-Using MSM [NA]
This Clinical Trial Update reports completion of Project MIX, a behavioral intervention study intended to reduce HIV risk among substance-us…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: Descriptive Analysis of Changes in Hepatitis B Markers in People Living With HIV on Injectable Therapy.
This clinical trial update provides a descriptive analysis of changes in Hepatitis B markers in people living with HIV who are on injectable…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study) [Phase 2]
Phase 2 study of semaglutide for non-alcoholic fatty liver disease in HIV infection completed, with results posted in May 2024.
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Study to Define Safety and Effectiveness of Dolutegravir (DTG) Use in Human Immunodeficiency Virus (HIV) Positive Pregnant Women
A clinical trial is studying the safety and effectiveness of dolutegravir use in HIV-positive pregnant women; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Impact of Probiotics in HIV-positive Patients With Neurocognitive Disorders [NA]
A completed clinical trial evaluated the impact of probiotics in HIV-positive patients with HIV-associated neurocognitive disorder.
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents [Phase 1, Phase 2]
The MOCHA study reports Phase 1/2 results for HIV-infected children and adolescents treated with oral and long-acting injectable cabotegravi…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Long-Term Follow-Up Study of HIV-1 Infected Adults Who Received EBT-101 [Phase 1]
The update describes the Phase 1 long-term follow-up study of HIV infection in adults who received EBT-101, with enrollment by invitation co…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Impact of COVID-19 on Provision and Uptake of Prevention of Mother-to-child Transmission of HIV Services in Zimbabwe
A completed clinical trial evaluating how COVID-19 affected the provision and uptake of HIV prevention of mother-to-child transmission servi…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Gut Microbiota, PGx and INSTIs Response
Completed clinical trial evaluating how gut microbiota and pharmacogenomics influence response to integrase inhibitors in HIV infection.
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Project WERK (Wellness Encouragement Respect Kinship) [NA]
A University of Chicago-sponsored clinical trial (Project WERK) evaluating HIV prevention has completed.
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Hybrid Evaluation of a Home-based HIV Pre-exposure Prophylaxis Program [NA]
A clinical trial evaluating a home-based HIV pre-exposure prophylaxis program is currently recruiting, led by the University of Washington.
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FDA approval · 2024-05-10FDA Approved: EFAVIRENZ — Original Application (Macleods Pharmaceuticals Limited)
FDA approved the generic efavirenz from Macleods Pharmaceuticals Limited under ANDA 091579. This action grants regulatory approval for the g…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject Drugs [Phase 4]
A Phase 4 trial evaluating Triumeq as an integrase single-tablet regimen for people with HIV who inject drugs was terminated.
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: BFTAF Elderly Switch Study [Phase 4]
A Phase 4 clinical trial conducted by the University of Nairobi evaluating an elderly-switch strategy for people with HIV-1 infection has co…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Effect of Aerobic Training and Ginkgo Biloba on Lipids Levels in HIV-positive Patients Undergoing Antiretroviral Treatment [Phase 2, Phase 3]
This completed Phase 2/3 trial evaluated the effect of combining aerobic training with Ginkgo biloba on lipid levels in HIV-positive patient…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures
Clinical trial update examining uptake, outcomes, and risk factors for treatment failures of the long-acting cabotegravir plus rilpivirine r…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: A Cohort for Evaluation of Open-label PrEP Use and PreP Preferences Among African Women
A completed cohort study evaluating open-label PrEP use and PrEP preferences among African women to inform HIV prevention strategies.