HIV Infection
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FDA approval · 2024-06-18FDA Approved: EFAVIRENZ — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for EFAVIRENZ from Aurobindo Pharma Limited, authorizing changes to the approved ANDA product (s…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide
A completed clinical trial evaluating the effectiveness, safety, adherence, and health-related quality of life in adults with HIV-1 infectio…
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: Pharmacokinetics Distribution of Raltegravir by PET/MR [EARLY_Phase 1]
An early Phase 1 pharmacokinetic study will assess the distribution of raltegravir in HIV-1-infected participants using PET/MR; the study is…
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV [NA]
Brown University is recruiting participants to study the health effects of a standardized research e-cigarette in smokers with HIV.
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FDA approval · 2024-06-14FDA Approved: ABACAVIR AND LAMIVUDINE — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' supplemental application for a generic fixed-dose combination of abacavir and lamivudine for the treatme…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort
This is a completed clinical trial update examining airway microbiome and Th17-mediated inflammation in chronic obstructive pulmonary diseas…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Technology Based Community Health Nursing to Improve Combination Anti-Retroviral Therapy (cART) Adherence and Virologic Suppression in Youth Living With HIV [NA]
This clinical trial update reports the completed study evaluating a technology-based community health nursing approach to improve adherence …
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma [Phase 2]
A Phase 2 trial evaluating Aldoxorubicin in HIV-infected individuals with Kaposi's sarcoma has completed enrollment and posted results in Ju…
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CLINICAL_TRIALS research · 2024-06-11Clinical Trial Update: A Study to Evaluate the Safety and Immunogenicity of 2 Doses of 100µg BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, Given to a Population of Adults Who Have Received 3 Doses of 300µg BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted [Phase 1]
A Phase 1 study evaluating the safety and immunogenicity of two doses of BG505 SOSIP.664 gp140 vaccine with adjuvant in adults who previousl…
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: Bioequivalence Study to Compare Dolutegravir 50mg Film-coated Tablets [Phase 1]
A Phase 1 bioequivalence study evaluating Dolutegravir 50 mg film-coated tablets has been completed.
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Assessment of Sleep Disordersin People Living With HIV in the Era of New Antiretroviral Therapies in North of France
A clinical trial evaluating sleep disorders in people living with HIV in northern France during the era of new antiretroviral therapies. The…
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: Integrating Hypertension Management in DSD for HIV
A clinical trial in Uganda aims to integrate hypertension management into differentiated service delivery for people living with HIV; the st…
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users [NA]
This clinical trial update notes completion and posting of results for a study evaluating interventions to improve adherence to HIV PrEP amo…
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FDA approval · 2024-06-04FDA Approved: RETACRIT — Supplemental Application (Vifor (International) Inc.)
The FDA approved a supplemental application for RETACRIT (epoetin alfa-epbx) submitted by Vifor (International) Inc.
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: HealthMindr App to Increase Pre-exposure Prophylaxis (PrEP) Uptake and Retention Among Men Who Have Sex With Men (MSM) [NA]
A completed clinical trial evaluated the HealthMindr app to increase uptake and retention of PrEP among men who have sex with men, with resu…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Connect 'n Unite: Couples-Based HIV/STI Prevention for Drug-Involved, Black MSM [NA]
The Connect 'n Unite trial, a couples-based HIV/STI prevention study for drug-involved Black men who have sex with men, has completed. No re…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Bictegravir in the Elderly Living With HIV (BICEP)
This clinical trial update indicates that a study of bictegravir in elderly adults living with HIV is active but not currently recruiting. T…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: ARCH Research Protocol for Provider Alcohol Pharmacotherapy Training and Assessment [NA]
A completed protocol study describing ARCH training and assessment for providers on pharmacotherapy of alcohol use disorder in the context o…
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: LIROH - Liraglutide for Obesity in HIV [Phase 4]
A Phase 4 clinical trial is evaluating liraglutide for obesity in people with HIV and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Changes in Weight, Body Composition and Cardiac Risk After Discontinuing Abacavir Treatment in HIV-infected Individuals [Phase 4]
Phase 4 trial update examining changes in weight, body composition and cardiac risk after stopping abacavir in HIV-infected individuals. The…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Evaluate and Optimize an Online Care Model for PrEP Delivery: Pilot Study [NA]
A completed pilot study evaluating and optimizing an online care model for delivering HIV PrEP.
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CLINICAL_TRIALS trial_result · 2024-05-28Clinical Trial Update: Study to Evaluate the Pharmacokinetics (PK), Safety, and Efficacy of B/F/TAF in Human Immunodeficiency Virus (HIV)-1 Infected, Virologically Suppressed, Pregnant Women in Their Second and Third Trimesters [Phase 1]
Phase 1 study results summarize pharmacokinetics, safety, and tolerability of the bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) …
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CLINICAL_TRIALS trial_result · 2024-05-28Clinical Trial Update: Sustainable Healthcenter Implementation PrEP Pilot Study
This entry provides an update on a completed pilot study evaluating implementation of pre-exposure prophylaxis (PrEP) for HIV prevention in …
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: HDV-Europe: Prevalence and Outcome of HDV in HIV/HBV Coinfection
HDV-Europe is an observational study assessing the prevalence and outcomes of hepatitis D in individuals with HIV and hepatitis B co-infecti…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: Within My Reach (WMR) Adaptation [NA]
A clinical trial titled 'Within My Reach (WMR) Adaptation' sponsored by the University of Miami has completed. The study involved HIV infect…