HIV Infection
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EMA withdrawal · 2026-03-27EMA Withdrawn: Atazanavir Krka (atazanavir (as sulfate)) — Krka, d.d., Novo mesto
EMA withdrew the Atazanavir Krka product (atazanavir sulfate) for HIV infections.
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CLINICAL_TRIALS withdrawal · 2026-03-05Clinical Trial Update: Pharmacokinetics Safety and Acceptability of DRV/r for Children Living With HIV [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the pharmacokinetics, safety, and acceptability of the darunavir/ritonavir combination in children liv…
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CLINICAL_TRIALS withdrawal · 2026-02-18Clinical Trial Update: HIV + Service Delivery and Telemedicine Through Effective PROs [NA]
Clinical trial evaluating HIV service delivery and telemedicine using patient-reported outcomes has been withdrawn. The study targeted HIV i…
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CLINICAL_TRIALS withdrawal · 2026-01-14Clinical Trial Update: CAbotégravir LENacapavir DUal Long Acting [Phase 2]
Phase 2 trial of dual long-acting cabotegravir and lenacapavir for HIV-1 infection has been withdrawn.
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EMA withdrawal · 2026-01-05EMA Withdrawn: Telzir (fosamprenavir calcium) — ViiV Healthcare BV
The European Medicines Agency has withdrawn the marketing authorization for Telzir (fosamprenavir calcium) for HIV infections.
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CLINICAL_TRIALS withdrawal · 2025-09-11Clinical Trial Update: Evaluating a Combination of Immune-based Therapies to Achieve a Remission of HIV Infection [Phase 1, Phase 2]
A phase 1/phase 2 clinical trial evaluating a combination of immune-based therapies for HIV infection has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-09-11Clinical Trial Update: Welcoming by Design Pilot: Reducing Structural Stigma by Changing Clinic Systems and Architectural Design [NA]
A clinical trial named Welcoming by Design Pilot aimed to reduce structural stigma in HIV care by changing clinic systems and architectural …
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CLINICAL_TRIALS withdrawal · 2025-08-28Clinical Trial Update: MyPrEP Plus: Development and Pilot Testing of Novel Preexposure Prophylaxis Decision Support Tools for Transgender Women [NA]
The MyPrEP Plus trial, which aimed to develop and pilot test decision-support tools for transgender women to aid HIV pre-exposure prophylaxi…
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CLINICAL_TRIALS withdrawal · 2025-07-31Clinical Trial Update: CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy [Phase 1, Phase 2]
The CREATE trial evaluating cabotegravir and rilpivirine for HIV-1 infection in pregnancy (Phase 1/Phase 2) has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-07-30Clinical Trial Update: Cost-effectiveness of Different Antiretroviral Treatment in Patients HIV Naive [Phase 4]
A Phase 4 trial evaluating the cost-effectiveness of different antiretroviral regimens in ART-naive HIV patients has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-07-11Clinical Trial Update: A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection [Phase 2]
The Phase 2 trial of UB-421 in combination with optimized background antiretroviral therapy for multi-drug resistant HIV-1 infection has bee…
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CLINICAL_TRIALS withdrawal · 2025-06-26Clinical Trial Update: Multiplo Near Patient Non-HCP Study [NA]
The Multiplo Near Patient Non-HCP Study has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-06-06Clinical Trial Update: Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men
The clinical trial investigating incidence of HPV infection and HPV-associated disease in screening Indian men who have sex with HIV-positiv…
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CLINICAL_TRIALS withdrawal · 2025-06-06Clinical Trial Update: Incidence of HIV Infection in Screening Indian Men Who Have Sex With Men
The trial NCT04142385 investigating incidence of HIV infection in screening Indian men who have sex with men has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-05-20Clinical Trial Update: An Effectiveness Trial of the PrEP for WINGS Study [NA]
The PrEP for WINGS effectiveness trial has been withdrawn; no results are reported. The listed conditions include HIV infection and alcohol …
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CLINICAL_TRIALS withdrawal · 2025-04-22Clinical Trial Update: VH3739937 Phase 1 Multiple Ascending Dose (MAD) Study in Healthy Volunteers Including Relative Bioavailability (RBA), Optional Food Effect (FE), and Drug-drug Interaction (DDI) [Phase 1]
Phase 1 MAD study of VH3739937 in healthy volunteers has been withdrawn, including assessments of relative bioavailability, food effect, and…
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CLINICAL_TRIALS withdrawal · 2025-03-26Clinical Trial Update: A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum [Phase 1]
A Phase 1 HIV vaccine trial evaluating CH505M5 Pr-NP1 followed by CH505 TF chTrimer boost with LNPs or 3M-052-AF + Alum was withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-03-14Clinical Trial Update: Mosaic HIV-1 Envelope Trimer Immunogens Administered to People Living with HIV (PLWH) in Africa [EARLY_Phase 1]
A EARLY Phase 1 clinical trial evaluating Mosaic HIV-1 Envelope Trimer immunogens in people living with HIV in Africa has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-02-27Clinical Trial Update: Suubi4Cancer: Improving Access to Pediatric Cancer Services and Treatment Adherence Among Children Living With HIV/AIDS [NA]
Suubi4Cancer, a pediatric trial to improve access to cancer services and treatment adherence for children living with HIV/AIDS, has been wit…
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CLINICAL_TRIALS withdrawal · 2025-02-10Clinical Trial Update: Food Assistance, Diabetes, and HIV
The clinical trial NCT04045184 sponsored by the University of Alabama at Birmingham, studying the impact of food assistance on diabetes mell…
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CLINICAL_TRIALS withdrawal · 2024-12-18Clinical Trial Update: How Does Antiretroviral Therapy Affect Coronary Atherosclerosis: a Serial CT Study [Phase 4]
A Phase 4 clinical trial evaluating how antiretroviral therapy affects coronary atherosclerosis, monitored by serial CT scans, has been with…
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CLINICAL_TRIALS withdrawal · 2024-12-13Clinical Trial Update: Pharmacokinetic Interactions of ENG Subdermal Implants with Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA) [Phase 4]
A Phase 4 pharmacokinetic interaction study (CARLA) assessing etonogestrel subdermal implants with long-acting cabotegravir and rilpivirine …
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Measuring the HIV-1 Reservoir During Cure Interventions Studies (MERCI)
The MERCI study (NCT05783388) evaluating measuring the HIV-1 reservoir during cure interventions has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-07-03Clinical Trial Update: Teleneuropsychological Intervention in Asymptomatic HIV Seropositive Patients: N&C NeuroChange [NA]
This clinical trial update notes that the Teleneuropsychological Intervention trial (N&C NeuroChange) in asymptomatic HIV-seropositive indiv…
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CLINICAL_TRIALS withdrawal · 2024-05-03Clinical Trial Update: Safety and Efficacy of Neutralizing Antibodies and Vaccination for Induction of HIV Remission [Phase 1]
A Phase 1 clinical trial evaluating neutralizing antibodies and vaccination to induce HIV remission has been withdrawn.