HIV Infection
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care [NA]
This entry notes a Johns Hopkins clinical trial evaluating practice facilitation to improve the adoption and implementation of alcohol treat…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Enhancing PrEP Outcomes Among Kenyan Adolescent Girls and Young Women With a Novel Pharmacy-based PrEP Delivery Platform [NA]
A recruiting clinical trial in Kenya is testing a novel pharmacy-based PrEP delivery platform to improve PrEP outcomes among adolescent girl…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Multi-product PrEP Delivery to Young Women Seeking Reproductive Health Services and Coverage of HIV Prevention [Phase 4]
This clinical trial update describes a Phase 4 study evaluating multi-product PrEP delivery for HIV prevention among young women seeking rep…
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FDA approval · 2025-07-18FDA Approved: EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE — Supplemental Application (Laurus Labs Limited)
The FDA approved a supplemental application for a generic fixed-dose combination emtricitabine/tenofovir disoproxil fumarate by Laurus Labs …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Simplification Study of HIV-1 Infected Patients With Virological Suppression Under the Combination of Lamivudine (150 mg BID) Plus Raltegravir (400 mg BID) Switching to Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) : Roll-over Study of the RALAM [Phase 3]
Phase 3 trial results report on switching virologically suppressed HIV-1-infected patients from Lamivudine 150 mg BID plus Raltegravir 400 m…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Study to Evaluate the Efficacy and Safety of a Rilpivarine-based Antiretroviral Tratment Regimen in HIV- Infected Patients With Liver Metabolic Disease Who Maintain Udetectable HIV Viral Load [Phase 4]
A Phase 4 trial assessed the efficacy and safety of a rilpivirine-based antiretroviral regimen in HIV-infected patients with non-alcoholic f…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Virological and Immunological Safety of a Dose Reduction Strategy Antiretroviral Regimen With Efavirenz / Tenofovir / Emtricitabine [Phase 4]
Phase 4 trial assessing the virological and immunological safety of a dose-reduction strategy for an efavirenz/tenofovir/emtricitabine antir…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: DTG/3TC vs. BIC/FTC/TAF Maintenance Therapy in People Living With HIV: [Phase 4]
Phase 4 trial comparing dolutegravir/lamivudine (DTG/3TC) versus bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) as maintenanc…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Phase IV, a Clinical Trial to Assess Safety and Convenience of the Change From DTG/3TC to BIC/FTC/TAF in People With HIV, Good Virological Control and Neuropsychiatric Vulnerabilities [Phase 4]
Phase IV trial assessing safety and convenience of switching virologically controlled people with HIV from dolutegravir/lamivudine to bicteg…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: The University of Zimbabwe College of Health Science (UZ-CHS) BIRTH COHORT Study
The University of Zimbabwe College of Health Sciences is conducting the BIRTH COHORT study focusing on HIV infections and immune activation,…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Patient-provider Decision Aid for HIV Post-exposure Prophylaxis Following Sexual Assault [NA]
A clinical trial is evaluating a patient-provider decision aid to guide HIV post-exposure prophylaxis after sexual assault; the study is cur…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine M72/AS01E in Participants With Well-controlled HIV [Phase 2]
A Phase 2 trial evaluated the safety and immunogenicity of the tuberculosis vaccine M72/AS01E in people with well-controlled HIV, with resul…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Towards a Functional Cure for HBV - The COMMIT Cohort Study
The COMMIT Cohort Study investigating functional cure approaches for hepatitis B in HIV/HBV coinfected individuals is currently active but n…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
AIDS Malignancy Consortium is recruiting for a study to collect blood and tissue samples from participants with HIV/AIDS-related cancers to …
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV [Phase 2]
Phase 2 trial evaluating cenicriviroc mesylate for reducing arterial inflammation in people living with HIV has completed with results poste…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Can INSTI-associated Weight Gain be Halted or Reversed With a Switch to Doravirine/Lamivudine/Tenofovir DF? [Phase 4]
A Phase 4 trial investigated whether switching to the fixed-dose combination doravirine/lamivudine/tenofovir disoproxil fumarate could halt …
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: The Blued+ Combination HIV Prevention Pilot Study in China
The Blued+ combination HIV prevention pilot trial in China has completed, with results posted in 2025.
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Cholesterol Levels [Phase 4]
Phase 4 trial comparing rosuvastatin to switching protease inhibitors in people with HIV and high cholesterol; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: A Study of Teropavimab and Zinlirvimab in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection [Phase 2]
Phase 2 study evaluating teropavimab and zinlirvimab in combination with lenacapavir for virologically suppressed adults with HIV-1 infectio…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV [NA]
A clinical trial update announcing the recruitment of participants for an enhanced mentor mother strategy to support pregnant and postpartum…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Implementation of Out-of-HOspital Administration of the Long-Acting Cabotegravir+Rilpivirine [Phase 4]
This Phase 4 clinical trial update reports on the out-of-hospital administration of the long-acting cabotegravir plus rilpivirine regimen fo…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Community-based, Peer-delivered PrEP for Female Sex Workers in Rural Uganda: The Peers for PrEP (P4P) Study [NA]
A community-based study in rural Uganda is evaluating peer-delivered pre-exposure prophylaxis (PrEP) for female sex workers; the trial is cu…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Using Smart Phone Technology to Support HIV Medication Refill Adherence in Virginia [NA]
A completed clinical trial from the University of Virginia evaluated using smartphone technology to support adherence to HIV medication refi…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Change My Story Task Shifted Mental Health Intervention [NA]
This clinical trial update notes a task-shifted mental health intervention called 'Change My Story' for people with HIV and depression, and …
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs [NA]
A systems-analysis approach to optimize HIV service delivery within Syringe Services Programs; the trial is currently active but not recruit…