Clinical Trial Update: Can INSTI-associated Weight Gain be Halted or Reversed With a Switch to Doravirine/Lamivudine/Tenofovir DF? [Phase 4]

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Summary

A Phase 4 trial investigated whether switching to the fixed-dose combination doravirine/lamivudine/tenofovir disoproxil fumarate could halt or reverse INSTI-ass…

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Diseases / indications

• HIV Infection

Drugs mentioned

• DELSTRIGO (DORAVIRINE, LAMIVUDINE, TENOFOVIR DISOPROXIL FUMARATE)

Snippet

Sponsor: University Health Network, Toronto | Conditions: Hiv, Weight Gain | Phase 4 | Status: TERMINATED | Results posted: 2025-07-16