High-grade Squamous Intraepithelial Lesion
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Does Hr-HPV Status Influence the 2011 IFCPC Nomenclature and Swede Score's Capacity to Diagnose Precancerous Lesions?
A completed clinical trial evaluated whether hr-HPV status influences the 2011 IFCPC nomenclature and Swede Score in diagnosing precancerous…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions [Phase 3]
Phase 3 randomized trial comparing imiquimod, fluorouracil, or observation in HIV-positive individuals with high-grade anal intraepithelial …
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2 [Phase 2]
Phase 2 trial of VGX-3100 delivered intramuscularly with electroporation for HPV-16/18 associated HSIL in HIV-seronegative individuals; stud…
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CLINICAL_TRIALS trial_result · 2022-07-13Clinical Trial Update: An Exploratory Safety and Immunogenicity Study of HPV16+ Immunotherapy VB10.16 in Women With HSIL; CIN 2/3) [Phase 1, Phase 2]
Phase 1/2 exploratory study evaluating safety and immunogenicity of HPV16+ immunotherapy VB10.16 in women with high-grade cervical intraepit…
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Study of Pomalidomide in Anal Cancer Precursors [Phase 2]
Phase 2 study investigating pomalidomide in high-grade squamous intraepithelial lesion (HSIL) precursors; current status is unknown.
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CLINICAL_TRIALS trial_result · 2019-02-07Clinical Trial Update: Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection [Phase 1]
A Phase 1 study evaluating topical ABI-1968 in subjects with precancerous anal lesions caused by HPV has completed.
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CLINICAL_TRIALS trial_result · 2017-10-05Clinical Trial Update: A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand [Phase 2]
Phase 2 trial evaluating circumferential anal canal radiofrequency ablation for high-grade anal intraepithelial neoplasia using the BARRX an…
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CLINICAL_TRIALS trial_result · 2013-06-03Clinical Trial Update: SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells [Phase 2]
Phase 2 clinical trial of the SGN-00101 vaccine for HPV-related cervical cell abnormalities has completed.